> Hexosaminidase A (alpha polypeptide) (HEXA)
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UGID:2073490     UniGene Hs.604479     Homo sapiens (human)   HEXA Order cDNA clone, Links
Hexosaminidase A (alpha polypeptide) (HEXA)

Human protein-coding gene HEXA. Represented by 834 ESTs from 320 cDNA libraries. Corresponds to reference sequence NM_000520.4. [UniGene 2073490 - Hs.604479]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001175124.1 PREDICTED: beta-hexosaminidase subunit alpha isoform 9 P. troglodytes 100.0 528
NP_000511.2 HEXA gene product H. sapiens 100.0 528
NP_034551.2 Hexa gene product M. musculus 90.9 527
NP_001017763.1 zgc:112084 gene product D. rerio 66.5 516
NP_508409.1 Protein HEX-1 C. elegans 49.6 413
NP_176737.2 beta-hexosaminidase 3 A. thaliana 46.7 214
Other hits (2 of 48) [Show all]SpeciesId(%)Len(aa)
XP_002804898.1 PREDICTED: beta-hexosaminidase subunit alpha M. mulatta 99.1 539
XP_003901204.1 PREDICTED: beta-hexosaminidase subunit alpha isoform 2 P. anubis 99.1 539

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; placenta; lung; skin; intestine; mixed; kidney; heart; cervix; nerve; adrenal gland; mammary gland; connective tissue; eye; thyroid; pancreas; uterus; blood; testis; umbilical cord; thymus; ascites; tonsil; ovary; embryonic tissue; salivary gland; pituitary gland; spleen; prostate; bladder; esophagus; stomach; bone; liver; lymph node; trachea; larynx; pharynx; bone marrow; muscle; vascular; adipose tissue; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q24.1
UniSTS entry: Chr 15 GDB:176311
UniSTS entry: Chr 15 RH98547
UniSTS entry: Chr 15 SHGC-33452 [Map Viewer]
UniSTS entry: Chr 15 WI-7120
UniSTS entry: Chr 15 GDB:177101
UniSTS entry: Chr 15 RH44590
UniSTS entry: Chr 15 SHGC-35689 [Map Viewer]
UniSTS entry: Chr 15 RH48983
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

BX537989.1 Homo sapiens mRNA; cDNA DKFZp686A148 (from clone DKFZp686A148) PA
NM_000520.4 Homo sapiens hexosaminidase A (alpha polypeptide) (HEXA), mRNA P
BC021030.1 Homo sapiens hexosaminidase A (alpha polypeptide), mRNA (cDNA clone IMAGE:3626334), partial cds P
CR627386.1 Homo sapiens mRNA; cDNA DKFZp781C13106 (from clone DKFZp781C13106) PA
BC084537.1 Homo sapiens hexosaminidase A (alpha polypeptide), mRNA (cDNA clone MGC:99608 IMAGE:5459166), complete cds PA
AK222502.1 Homo sapiens mRNA for hexosaminidase A preproprotein variant, clone: adSE00402 PA
BC001138.2 Homo sapiens hexosaminidase A (alpha polypeptide), mRNA (cDNA clone IMAGE:2989846), partial cds PA
BC018927.2 Homo sapiens hexosaminidase A (alpha polypeptide), mRNA (cDNA clone MGC:14125 IMAGE:3353424), complete cds PA
AK307770.1 Homo sapiens cDNA, FLJ97718 P
AK310154.1 Homo sapiens cDNA, FLJ17196 P
AK301138.1 Homo sapiens cDNA FLJ50884 complete cds, highly similar to Beta-hexosaminidase alpha chain precursor (EC 3.2.1.52) P
AK301000.1 Homo sapiens cDNA FLJ53927 complete cds, highly similar to Beta-hexosaminidase alpha chain precursor (EC 3.2.1.52) P
AK297678.1 Homo sapiens cDNA FLJ60712 complete cds, moderately similar to Beta-hexosaminidase alpha chain precursor (EC 3.2.1.52) P
AK296528.1 Homo sapiens cDNA FLJ60630 complete cds, highly similar to Beta-hexosaminidase alpha chain precursor (EC 3.2.1.52) P
M13520.1 Human alpha-polypeptide of N-acetyl-alpha-glucosaminidase (HEXA), mRNA, 3'end P
J04178.1 Human abnormal beta-hexosaminidase alpha chain (HEXA) mRNA, partial cds

EST sequences (10 of 834) [Show all sequences]

AA993472.1 Clone IMAGE:1618625 testis 3' read P
AA994088.1 Clone IMAGE:1630734 mammary gland 3' read
AA996314.1 Clone IMAGE:1605876 kidney 3' read A
AA907603.1 Clone IMAGE:1540585 mixed 3' read A
AI027370.1 Clone IMAGE:1649902 parathyroid 3' read A
AI027381.1 Clone IMAGE:1650124 parathyroid 3' read A
T05970.1 Clone HFBDK30 brain
AI041920.1 Clone IMAGE:1664600 skin 3' read P
AA921680.1 Clone IMAGE:1536872 kidney 3' read A
AI139546.1 Clone IMAGE:1713282 uterus 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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