> Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) (GOT2)
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UGID:2068481     UniGene Hs.599470     Homo sapiens (human)   GOT2 Order cDNA clone, Links
Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) (GOT2)

Human protein-coding gene GOT2. Represented by 1972 ESTs from 435 cDNA libraries. Corresponds to reference sequence NM_002080.2. [UniGene 2068481 - Hs.599470]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003917024.1 PREDICTED: aspartate aminotransferase, mitochondrial P. anubis 100.0 429
XP_523381.2 PREDICTED: aspartate aminotransferase, mitochondrial isoform 2 P. troglodytes 100.0 429
NP_002071.2 GOT2 gene product H. sapiens 100.0 429
XP_001103601.1 PREDICTED: aspartate aminotransferase, mitochondrial M. mulatta 99.5 429
NP_034455.1 Got2 gene product M. musculus 97.2 429
NP_001080255.1 aspartate aminotransferase 2 X. laevis 88.8 426
NP_998544.1 got2a gene product D. rerio 86.7 427
NP_741810.1 Protein GOT-2.2, isoform a C. elegans 73.5 407
XP_001728110.1 aspartate aminotransferase, mitochondrial N. crassa 69.1 424
NP_608636.1 glutamate oxaloacetate transaminase 2, isoform C D. melanogaster 67.9 392
NP_180654.1 aspartate aminotransferase A. thaliana 60.5 420
XP_001700039.1 aspartate aminotransferase C. reinhardtii 57.0 419
NP_013127.2 aspartate transaminase AAT2 S. cerevisiae 48.2 409
Other hits (2 of 61) [Show all]SpeciesId(%)Len(aa)
XP_002711597.1 PREDICTED: Aspartate aminotransferase, mitochondrial-like O. cuniculus 97.0 429
NP_037309.1 Got2 gene product R. norvegicus 96.5 429

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; liver; lung; kidney; uncharacterized tissue; heart; skin; prostate; placenta; intestine; eye; mixed; uterus; muscle; mouth; embryonic tissue; spleen; mammary gland; trachea; thyroid; lymph; vascular; thymus; stomach; ovary; blood; connective tissue; ascites; adrenal gland; pancreas; tonsil; pituitary gland; bladder; nerve; ganglia; lymph node; cervix; bone marrow; adipose tissue; esophagus; bone; amniotic fluid; salivary gland; umbilical cord; parathyroid; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q21
UniSTS entry: Chr 1 GDB:451676
UniSTS entry: Chr 16 D16S2550E
UniSTS entry: Got2
UniSTS entry: G20480
UniSTS entry: A005T19
UniSTS entry: Chr 1 D10S275
UniSTS entry: Chr 1 D1S1425
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_002080.2 Homo sapiens glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) (GOT2), nuclear gene encoding mitochondrial protein, mRNA PA
AK223271.1 Homo sapiens mRNA for aspartate aminotransferase 2 precursor variant, clone: STM08437 P
BC000525.2 Homo sapiens glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2), mRNA (cDNA clone MGC:8599 IMAGE:2961181), complete cds PA
AK290847.1 Homo sapiens cDNA FLJ78439 complete cds, highly similar to Homo sapiens glutamic-oxaloacetic transaminase 2 P
AK307598.1 Homo sapiens cDNA, FLJ97546 P
AK098313.1 Homo sapiens cDNA FLJ40994 fis, clone UTERU2015640, highly similar to Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) P
AK295993.1 Homo sapiens cDNA FLJ55692 complete cds, highly similar to Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) P
AK302249.1 Homo sapiens cDNA FLJ54203 complete cds, highly similar to Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) P
AL360255.1 Homo sapiens EST from clone 2210156, 3' end A
M22632.1 Human mitochondrial aspartate aminotransferase mRNA, complete cds P

EST sequences (10 of 1972) [Show all sequences]

AA985064.1 Clone IMAGE:1616139 brain 3' read
AA985655.1 Clone IMAGE:1601290 lung 3' read A
AA923535.1 Clone IMAGE:1536192 kidney 3' read A
T06019.1 Clone HFBDN02 brain
AI061068.1 Clone IMAGE:1699448 kidney 3' read A
AA948692.1 Clone IMAGE:1589665 kidney 3' read A
AI091588.1 Clone IMAGE:1682968 parathyroid 3' read A
AI091598.1 Clone IMAGE:1682965 parathyroid 3' read A
AI096615.1 Clone IMAGE:1704180 brain 3' read A
AI096843.1 Clone IMAGE:1702540 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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