> Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB)
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UGID:2066675     UniGene Hs.597664     Homo sapiens (human)   IKBKB Links
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB)

Human protein-coding gene IKBKB. Represented by 432 ESTs from 202 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 2066675 - Hs.597664]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001096913.1 PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1 M. mulatta 100.0 755
NP_001547.1 IKBKB gene product H. sapiens 100.0 755
XP_003902738.1 PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1 P. anubis 99.9 755
XP_001142461.2 PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit beta isoform 3 P. troglodytes 99.9 746
NP_001153246.1 Ikbkb gene product M. musculus 96.3 755
NP_001085125.1 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta X. laevis 82.1 733
NP_001116737.1 inhibitor of nuclear factor kappa-B kinase subunit beta D. rerio 71.0 776
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
NP_001093405.1 IKBKB gene product S. scrofa 98.2 754
XP_539954.2 PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit beta C. lupus familiaris 98.0 754

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uterus; skin; uncharacterized tissue; mouth; thyroid; bladder; adrenal gland; larynx; intestine; pituitary gland; eye; muscle; embryonic tissue; thymus; ovary; spleen; lymph node; liver; trachea; stomach; lung; mixed; placenta; kidney; connective tissue; ear; pancreas; mammary gland; blood; pharynx; bone; vascular; adipose tissue; prostate; salivary gland; cervix; heart; lymph; ganglia; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p11.2
UniSTS entry: Chr 8 STS-N21119 [Map Viewer]
UniSTS entry: Chr 8 RH104595
UniSTS entry: Chr 8 RH75091
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 15 RH67507
UniSTS entry: Chr 15 G32815
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (22)

AF031416.1 Homo sapiens IkB kinase beta subunit mRNA, complete cds P
AF080158.1 Homo sapiens IkB kinase-b (IKK-beta) mRNA, complete cds PA
NM_001556.2 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 1, mRNA P
BC090865.1 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, mRNA (cDNA clone IMAGE:6184761), with apparent retained intron PA
BC006231.2 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, mRNA (cDNA clone IMAGE:3945886), complete cds PA
BC127663.1 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, mRNA (cDNA clone IMAGE:40128020), partial cds P
BC141978.1 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, mRNA (cDNA clone IMAGE:40128022), partial cds P
AK290952.1 Homo sapiens cDNA FLJ77419 complete cds P
AK091297.1 Homo sapiens cDNA FLJ33978 fis, clone DFNES2004354, highly similar to Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) P
AK298241.1 Homo sapiens cDNA FLJ58600 complete cds, highly similar to Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) PA
AK303528.1 Homo sapiens cDNA FLJ58217 complete cds, highly similar to Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) P
AK303294.1 Homo sapiens cDNA FLJ58658 complete cds, highly similar to Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) P
AK302723.1 Homo sapiens cDNA FLJ57238 complete cds, highly similar to Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) P
AF029684.1 Homo sapiens IkB kinase-beta (IKK-beta) mRNA, partial cds P
BC144080.1 Homo sapiens cDNA clone IMAGE:9052600 P
AK316418.1 Homo sapiens cDNA, FLJ79317 complete cds, highly similar to Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) P
NM_001190720.2 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 2, mRNA P
HM245392.1 Homo sapiens TNPO1-IKBKB breakpoint junction mRNA sequence
NM_001242778.1 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 7, mRNA P
NR_033819.1 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 6, non-coding RNA P
NR_040009.1 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 8, non-coding RNA P
NR_033818.1 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 5, non-coding RNA P

EST sequences (10 of 432) [Show all sequences]

AA909406.1 Clone IMAGE:1542688 mixed 3' read
AI041036.1 Clone IMAGE:1642582 testis 3' read A
CB049560.1 Clone IMAGE:3271446 prostate 5' read A
BX097180.1 Clone IMAGp998P021113_;_IMAGE:469873 uterus
AI191615.1 Clone IMAGE:1734048 testis 3' read A
AI207161.1 Clone IMAGE:1941949 uncharacterized tissue 3' read
AI264203.1 Clone IMAGE:1857093 mixed 3' read
AI336571.1 Clone IMAGE:2051697 lung 3' read P
AI360553.1 Clone IMAGE:2005589 pancreas 3' read A
AI379342.1 Clone IMAGE:2070306 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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