> Hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD)
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UGID:2065924     UniGene Hs.596913     Homo sapiens (human)   HPGD Order cDNA clone, Links
Hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD)

Human protein-coding gene HPGD. Represented by 471 ESTs from 113 cDNA libraries. EST representation biased toward adult. Corresponds to 6 reference sequences (different isoforms). [UniGene 2065924 - Hs.596913]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003899423.1 PREDICTED: 15-hydroxyprostaglandin dehydrogenase [NAD(+)] P. anubis 100.0 265
XP_517542.2 PREDICTED: 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 4 P. troglodytes 100.0 265
NP_000851.2 HPGD gene product H. sapiens 100.0 265
XP_001087957.1 PREDICTED: 15-hydroxyprostaglandin dehydrogenase [NAD+] isoform 5 M. mulatta 99.6 265
NP_032304.2 Hpgd gene product M. musculus 94.8 268
NP_001086976.1 hydroxyprostaglandin dehydrogenase 15-(NAD) X. laevis 73.9 263
XP_694331.5 PREDICTED: 15-hydroxyprostaglandin dehydrogenase [NAD+]-like D. rerio 61.1 257
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_002709368.1 PREDICTED: hydroxyprostaglandin dehydrogenase 15-(NAD) O. cuniculus 97.7 260
NP_001177177.1 HPGD gene product S. scrofa 97.0 265

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; uterus; intestine; lung; bladder; kidney; liver; stomach; mixed; prostate; brain; pharynx; uncharacterized tissue; mammary gland; embryonic tissue; skin; muscle; cervix; mouth; pancreas; bone marrow; eye; testis; connective tissue; spleen; heart; esophagus; ear; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q34-q35
UniSTS entry: Chr 4 D4S3150 [Map Viewer]
UniSTS entry: Chr 4 SHGC-59688 [Map Viewer]
UniSTS entry: Chr 4 SHGC-59842
UniSTS entry: Chr 4 SHGC-67317 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

NM_000860.5 Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), transcript variant 1, mRNA PA
X82460.1 H.sapiens mRNA for 15-hydroxy prostaglandin dehydrogenase P
J05594.1 Homo sapiens NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (PDGH) mRNA, complete cds P
L76465.1 Homo sapiens NAD+-dependent 15 hydroxyprostaglandin dehydrogenase (PGDH) mRNA, complete cds P
AK058013.1 Homo sapiens cDNA FLJ25284 fis, clone STM06787, highly similar to 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] (EC 1.1.1.141) P
BC018986.2 Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD), mRNA (cDNA clone MGC:20092 IMAGE:3638799), complete cds PA
AK314624.1 Homo sapiens cDNA, FLJ95465, highly similar to Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), mRNA P
AK300940.1 Homo sapiens cDNA FLJ51962 complete cds, highly similar to 15-hydroxyprostaglandin dehydrogenase [NAD+](EC 1.1.1.141) (PGDH) P
AK300524.1 Homo sapiens cDNA FLJ50680 complete cds, highly similar to 15-hydroxyprostaglandin dehydrogenase [NAD+](EC 1.1.1.141) (PGDH) P
AK300125.1 Homo sapiens cDNA FLJ50664 complete cds, highly similar to Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), mRNA P
BC007691.2 Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD), mRNA (cDNA clone IMAGE:3955175), partial cds PA
AK296642.1 Homo sapiens cDNA FLJ50560 complete cds, highly similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (EC 1.1.1.141) (PGDH) P
NM_001145816.2 Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), transcript variant 2, mRNA PA
NM_001256307.1 Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), transcript variant 6, mRNA PA
NM_001256306.1 Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), transcript variant 5, mRNA PA
NM_001256301.1 Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), transcript variant 3, mRNA PA
NM_001256305.1 Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), transcript variant 4, mRNA PA
U63296.1 Human 15-hydroxyprostaglandin dehydrogenase mRNA, complete cds P

EST sequences (10 of 471) [Show all sequences]

AI091447.1 Clone IMAGE:1651445 mixed 3' read
R21783.1 Clone IMAGE:130382 placenta 5' read
AI129234.1 Clone IMAGE:1711849 uterus 3' read
AI129551.1 Clone IMAGE:1712046 uterus 3' read A
BX114254.1 Clone IMAGp998A065722_;_IMAGE:2308877 uncharacterized tissue
BX091884.1 Clone IMAGp998O03194_;_IMAGE:136154 placenta
AI190482.1 Clone IMAGE:1731766 heart 3' read P
AI192457.1 Clone IMAGE:1722681 placenta 3' read A
AI202552.1 Clone IMAGE:1943001 prostate 3' read P
CB157346.1 Clone L17N670205n1-3-D03 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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