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UGID:2065654     UniGene Hs.596643     Homo sapiens (human)   SLC7A8
Solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8)

Human protein-coding gene SLC7A8. Represented by 412 ESTs from 165 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 2065654 - Hs.596643]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001161755.1 PREDICTED: large neutral amino acids transporter small subunit 2 isoform 6 P. troglodytes 100.0 534
NP_036376.2 SLC7A8 gene product H. sapiens 100.0 534
XP_001106771.1 PREDICTED: large neutral amino acids transporter small subunit 2 isoform 3 M. mulatta 99.6 534
XP_003901636.1 PREDICTED: large neutral amino acids transporter small subunit 2 P. anubis 99.6 534
NP_058668.1 large neutral amino acids transporter small subunit 2 M. musculus 97.9 530
NP_001079655.1 uncharacterized protein LOC379342 X. laevis 95.4 524
XP_001344096.1 PREDICTED: large neutral amino acids transporter small subunit 2 D. rerio 93.2 518
NP_651865.1 CG1607, isoform A D. melanogaster 56.2 500
NP_501707.1 Protein AAT-1 C. elegans 54.4 489
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
NP_445894.1 Slc7a8 gene product R. norvegicus 97.9 532
XP_547730.1 PREDICTED: large neutral amino acids transporter small subunit 2 isoform 1 C. lupus familiaris 97.9 531

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; brain; skin; testis; pancreas; eye; larynx; intestine; bone marrow; esophagus; embryonic tissue; mouth; mixed; prostate; mammary gland; kidney; uncharacterized tissue; ovary; thyroid; parathyroid; uterus; trachea; thymus; connective tissue; lung; liver; muscle; bladder; blood; stomach; spleen; vascular; bone; adipose tissue; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q11.2
UniSTS entry: Chr 14 RH99158
UniSTS entry: Chr 14 D14S1252
UniSTS entry: Chr 14 RH69320
UniSTS entry: Chr 14 RH68931
UniSTS entry: D13S866E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (28)

BX248288.1 human full-length cDNA clone CS0DI068YA06 of Placenta of Homo sapiens (human) P
BC052250.1 Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 8, mRNA (cDNA clone MGC:59794 IMAGE:6260264), complete cds PA
Y18483.1 Homo sapiens mRNA for SLC7A8 protein PA
AF087911.1 Homo sapiens integral membrane protein E16H mRNA, complete cds P
AF087908.1 Homo sapiens TA1 mRNA, complete cds P
NM_182728.2 Homo sapiens solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8), transcript variant 2, mRNA PA
NM_012244.3 Homo sapiens solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8), transcript variant 1, mRNA PA
AL365342.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 645435 PA
AL365344.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 267666 PA
AL365345.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 249835 PA
AL365346.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 264148 A
AL365347.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 298948 A
AL365343.2 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 32539 PA
AL365414.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 322502 PA
AF135829.1 Homo sapiens clone IMAGE:267204 L amino acid transporter-2 (SLC7A8) mRNA, partial cds P
AF135830.1 Homo sapiens clone IMAGE:249835 L amino acid transporter-2 (SLC7A8) mRNA, partial cds PA
AF171669.1 Homo sapiens glycoprotein-associated amino acid transporter LAT2 (LAT2) mRNA, complete cds PA
AK223610.1 Homo sapiens mRNA for solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 isoform a variant, clone: FCC132G07 P
AB037669.1 Homo sapiens hLAT2 mRNA for L-type amino acid transporter 2, complete cds PA
AK313465.1 Homo sapiens cDNA, FLJ94010, highly similar to Homo sapiens solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (SLC7A8), mRNA P
AK307609.1 Homo sapiens cDNA, FLJ97557 P
AK300384.1 Homo sapiens cDNA FLJ53656 complete cds, highly similar to Large neutral amino acids transporter small subunit 2 P
AK296702.1 Homo sapiens cDNA FLJ53351 complete cds, highly similar to Large neutral amino acids transporter small subunit 2 P
BC036825.1 Homo sapiens, clone IMAGE:5191998, mRNA, partial cds PA
AF135828.1 Homo sapiens clone IMAGE:322502 L amino acid transporter-2 (SLC7A8) mRNA, partial cds P
NM_001267036.1 Homo sapiens solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8), transcript variant 3, mRNA PA
NM_001267037.1 Homo sapiens solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8), transcript variant 4, mRNA PA
NR_049767.1 Homo sapiens solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8), transcript variant 5, non-coding RNA PA

EST sequences (10 of 412) [Show all sequences]

AI016534.1 Clone IMAGE:1618431 testis 3' read A
AI025941.1 Clone IMAGE:1645891 parathyroid 3' read
AI042331.1 Clone IMAGE:1668037 parathyroid 3' read
R20108.1 Clone IMAGE:32539 brain 5' read
CB052941.1 Clone IMAGE:3290462 uncharacterized tissue 3' read A
CB052942.1 Clone IMAGE:3290462 uncharacterized tissue 5' read
CB068651.1 Clone IMAGE:6553837 pancreas 3' read A
CB069916.1 Clone IMAGE:6553837 pancreas 5' read
BX118833.1 Clone IMAGp998G19209_;_IMAGE:141738 placenta
AI249760.1 Clone IMAGE:1864285 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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