> Sodium channel, voltage-gated, type VII, alpha subunit (SCN7A)
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UGID:2065098     UniGene Hs.596087     Homo sapiens (human)   SCN7A Links
Sodium channel, voltage-gated, type VII, alpha subunit (SCN7A)

Human protein-coding gene SCN7A. Represented by 65 ESTs from 30 cDNA libraries. EST representation biased toward ear. Corresponds to 2 reference sequences (different isoforms). [UniGene 2065098 - Hs.596087]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002967.2 SCN7A gene product H. sapiens 100.0 1681
NP_033161.2 sodium channel, voltage-gated, type VII, alpha polypeptide M. musculus 76.7 1680
NP_001034914.1 scn4aa gene product D. rerio 50.2 1696
NP_001188643.1 paralytic, isoform AV D. melanogaster 46.6 238
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_515875.4 PREDICTED: sodium channel protein type 7 subunit alpha P. troglodytes 98.0 1675
XP_003907611.1 PREDICTED: sodium channel protein type 7 subunit alpha P. anubis 96.1 1680

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: ear [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: ear; embryonic tissue; placenta; prostate; pancreas; lung; mixed; muscle; testis; eye; heart; intestine; thymus; uterus; connective tissue; nerve; uncharacterized tissue; ganglia; liver
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q21-q23
UniSTS entry: Chr 2 A007J23
UniSTS entry: Chr 2 WI-9171
UniSTS entry: Chr 2 G59750
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_002976.3 Homo sapiens sodium channel, voltage-gated, type VII, alpha subunit (SCN7A), transcript variant 1, mRNA PA
BC062699.1 Homo sapiens sodium channel, voltage-gated, type VII, alpha, mRNA (cDNA clone IMAGE:4703945) PA
M91556.1 Human voltage-gated sodium channel mRNA, complete cds P
BC141864.1 Homo sapiens cDNA clone IMAGE:40071861 P
AK308450.1 Homo sapiens cDNA, FLJ98398 P
S75992.1 voltage-dependent sodium channel alpha subunit {3' region, fourth internal repeat} [human, myometrium, mRNA Partial, 206 nt]
NR_045628.1 Homo sapiens sodium channel, voltage-gated, type VII, alpha subunit (SCN7A), transcript variant 2, non-coding RNA PA

EST sequences (10 of 65) [Show all sequences]

AA970015.1 Clone IMAGE:1581347 mixed 3' read A
AI016423.1 Clone IMAGE:1622364 embryonic tissue 3' read A
AI039806.1 Clone IMAGE:1659664 embryonic tissue 3' read A
AI089166.1 Clone IMAGE:1634588 mixed 3' read A
BX111348.1 Clone IMAGp998P23199_;_IMAGE:138118 placenta
R25139.1 Clone IMAGE:131853 placenta 3' read A
AA911321.1 Clone IMAGE:1416976 lung 3' read
AI369952.1 Clone IMAGE:2049129 embryonic tissue 3' read
AI374884.1 Clone IMAGE:2048498 embryonic tissue 3' read A
AI381295.1 Clone IMAGE:2067973 embryonic tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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