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UGID:2063934     UniGene Hs.594923     Homo sapiens (human)   HSD17B11
Hydroxysteroid (17-beta) dehydrogenase 11 (HSD17B11)

Human protein-coding gene HSD17B11. Represented by 384 ESTs from 202 cDNA libraries. Corresponds to reference sequence NM_016245.3. [UniGene 2063934 - Hs.594923]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001157858.1 PREDICTED: estradiol 17-beta-dehydrogenase 11 isoform 3 P. troglodytes 100.0 299
NP_057329.2 HSD17B11 gene product H. sapiens 100.0 299
NP_444492.1 Hsd17b11 gene product M. musculus 86.9 297
NP_001086310.1 hydroxysteroid (17-beta) dehydrogenase 11 X. laevis 68.1 298
NP_998043.1 sdr16c5a gene product D. rerio 58.9 287
NP_610081.3 CG9265, isoform A D. melanogaster 51.2 244
NP_001122508.1 Protein DHS-3, isoform a C. elegans 49.6 250
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
XP_001096902.1 PREDICTED: estradiol 17-beta-dehydrogenase 11-like isoform 2 M. mulatta 96.3 299
XP_002717015.1 PREDICTED: estradiol 17-beta-dehydrogenase 11 O. cuniculus 92.6 298

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; placenta; muscle; ovary; spleen; adipose tissue; pharynx; testis; bladder; cervix; liver; pancreas; mixed; bone marrow; uterus; lung; embryonic tissue; adrenal gland; uncharacterized tissue; blood; lymph node; thymus; skin; eye; stomach; bone; mammary gland; connective tissue; vascular; kidney; esophagus; prostate; ear; salivary gland; ganglia; trachea; pituitary gland; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q22.1
UniSTS entry: Chr 4 D4S3294 [Map Viewer]
UniSTS entry: Chr 4 RH36051
UniSTS entry: Chr 4 WI-20423 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AY358553.1 Homo sapiens clone DNA34436 KFLL207 (UNQ207) mRNA, complete cds PA
NM_016245.3 Homo sapiens hydroxysteroid (17-beta) dehydrogenase 11 (HSD17B11), mRNA PA
AF126780.1 Homo sapiens retinal short-chain dehydrogenase/reductase retSDR2 mRNA, complete cds P
BC008650.1 Homo sapiens hydroxysteroid (17-beta) dehydrogenase 11, mRNA (cDNA clone MGC:8725 IMAGE:3854750), complete cds PA
BC014327.1 Homo sapiens hydroxysteroid (17-beta) dehydrogenase 11, mRNA (cDNA clone MGC:22858 IMAGE:3961721), complete cds PA
BC016367.1 Homo sapiens hydroxysteroid (17-beta) dehydrogenase 11, mRNA (cDNA clone MGC:24582 IMAGE:4133318), complete cds PA
BC021673.1 Homo sapiens hydroxysteroid (17-beta) dehydrogenase 11, mRNA (cDNA clone MGC:22824 IMAGE:3827935), complete cds PA
AF273056.1 Homo sapiens CTCL tumor antigen HD-CL-03 mRNA, complete cds PA
AK075348.1 Homo sapiens cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to Retinal short-chain dehydrogenase/reductase 2 P
BC011995.1 Homo sapiens cDNA clone IMAGE:3859111, containing frame-shift errors PA
BC036001.1 Homo sapiens hydroxysteroid (17-beta) dehydrogenase 11, mRNA (cDNA clone MGC:32825 IMAGE:4715042), complete cds PA

EST sequences (10 of 384) [Show all sequences]

R23903.1 Clone IMAGE:131057 placenta 5' read
R23904.1 Clone IMAGE:131057 placenta 3' read A
AI193508.1 Clone IMAGE:1744300 lung 3' read A
R27506.1 Clone IMAGE:132873 placenta 5' read P
R27885.1 Clone IMAGE:133786 placenta 5' read
AI262411.1 Clone IMAGE:1871153 intestine 3' read A
AI263974.1 Clone IMAGE:1874918 intestine 3' read
CB144012.1 Clone L16HLK3-23-C04 liver 5' read P
CB163647.1 Clone L17N670205n1-25-H08 liver 5' read
CB116013.1 Clone L8SCK0-12-D02 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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