> Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2)
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UGID:2063249     UniGene Hs.594238     Homo sapiens (human)   KPNA2 Order cDNA clone, Links
Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2)

Human protein-coding gene KPNA2. Represented by 2487 ESTs from 424 cDNA libraries. Corresponds to reference sequence NM_002266.2. [UniGene 2063249 - Hs.594238]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_002800621.1 PREDICTED: importin subunit alpha-2-like isoform 1 M. mulatta 100.0 528
NP_002257.1 KPNA2 gene product H. sapiens 100.0 528
NP_001233362.1 KPNA2 gene product P. troglodytes 99.8 528
XP_003913354.1 PREDICTED: importin subunit alpha-2-like P. anubis 99.6 528
NP_034785.1 Kpna2 gene product M. musculus 96.0 528
NP_001080459.1 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) X. laevis 81.2 525
NP_001002335.1 kpna2 gene product D. rerio 78.4 522
NP_477041.1 pendulin D. melanogaster 56.1 514
XP_001698656.1 importin alpha C. reinhardtii 55.4 529
NP_001154239.1 importin alpha isoform 2 A. thaliana 55.1 534
NP_501227.1 Protein IMA-3 C. elegans 53.0 504
NP_014210.1 Srp1p S. cerevisiae 51.9 528
XP_960652.1 importin alpha subunit N. crassa 51.7 532
Other hits (2 of 64) [Show all]SpeciesId(%)Len(aa)
XP_861990.1 PREDICTED: importin subunit alpha-2 isoform 2 C. lupus familiaris 99.0 528
NP_001156876.1 KPNA2 gene product S. scrofa 98.9 528

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; uncharacterized tissue; skin; embryonic tissue; uterus; stomach; eye; liver; placenta; ascites; mouth; connective tissue; mammary gland; intestine; mixed; kidney; thymus; blood; lung; prostate; pharynx; vascular; pancreas; ovary; heart; cervix; muscle; lymph; salivary gland; esophagus; lymph node; bone marrow; thyroid; tonsil; umbilical cord; bone; spleen; bladder; amniotic fluid; trachea; epididymis; adrenal gland; nerve; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q24.2
UniSTS entry: Chr 17 SHGC-11874 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BT006665.1 Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1) mRNA, complete cds P
BC053343.1 Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1), mRNA (cDNA clone MGC:61578 IMAGE:4450470), complete cds PA
NM_002266.2 Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2), mRNA PA
BC067848.1 Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1), mRNA (cDNA clone MGC:87448 IMAGE:4825235), complete cds PA
AK024833.1 Homo sapiens cDNA: FLJ21180 fis, clone CAS11176, highly similar to HSU28386 Human nuclear localization sequence receptor hSRP1alpha mRNA PA
BC005978.1 Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1), mRNA (cDNA clone MGC:14668 IMAGE:4105058), complete cds PA
AK058111.1 Homo sapiens cDNA FLJ25382 fis, clone TST02229, highly similar to IMPORTIN ALPHA-2 SUBUNIT P
AK291954.1 Homo sapiens cDNA FLJ78270 complete cds, highly similar to Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1)(KPNA2), mRNA P
U09559.1 Human Rch1 (RCH1) mRNA, complete cds P
BC034443.1 Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1), mRNA (cDNA clone IMAGE:4824211) PA
BC013257.1 Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1), mRNA (cDNA clone IMAGE:3867599) PA
BC146905.1 Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1), mRNA (cDNA clone MGC:182008 IMAGE:9056833), complete cds P
U28386.1 Human nuclear localization sequence receptor hSRP1alpha mRNA, complete cds PA

EST sequences (10 of 2487) [Show all sequences]

AA974509.1 Clone IMAGE:1420978 intestine 3' read PA
AA993290.1 Clone IMAGE:1623947 embryonic tissue 3' read PA
AI023440.1 Clone IMAGE:1654586 mixed 3' read P
AI026810.1 Clone IMAGE:1645656 testis 3' read P
AI039755.1 Clone IMAGE:1657335 embryonic tissue 3' read A
AI082013.1 Clone IMAGE:1678602 mixed 3' read A
AI089353.1 Clone IMAGE:1695422 uterus 3' read P
AI142361.1 Clone IMAGE:1839918 testis 5' read P
AI147354.1 Clone IMAGE:1839918 testis 3' read P
BX090180.1 Clone IMAGp998M1818_;_IMAGE:66617 mixed P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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