> Isocitrate dehydrogenase 1 (NADP+), soluble (IDH1)
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UGID:2062433     UniGene Hs.593422     Homo sapiens (human)   IDH1 Order cDNA clone, Links
Isocitrate dehydrogenase 1 (NADP+), soluble (IDH1)

Human protein-coding gene IDH1. Represented by 834 ESTs from 296 cDNA libraries. Corresponds to reference sequence NM_005896.2. [UniGene 2062433 - Hs.593422]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001141655.1 PREDICTED: isocitrate dehydrogenase [NADP] cytoplasmic isoform 1 P. troglodytes 100.0 413
NP_005887.2 IDH1 gene product H. sapiens 100.0 413
XP_001107810.1 PREDICTED: isocitrate dehydrogenase [NADP] cytoplasmic isoform 2 M. mulatta 99.8 413
XP_003907935.1 PREDICTED: isocitrate dehydrogenase [NADP] cytoplasmic isoform 1 P. anubis 99.8 413
NP_034627.3 Idh1 gene product M. musculus 97.3 413
NP_001088022.1 isocitrate dehydrogenase 1 X. laevis 93.0 414
NP_958907.1 idh1 gene product D. rerio 88.8 420
NP_501665.1 hypothetical protein F59B8.2 C. elegans 85.1 409
NP_729368.1 isocitrate dehydrogenase, isoform A D. melanogaster 82.9 410
XP_955850.1 hypothetical protein NCU03857 N. crassa 79.3 411
XP_001698704.1 isocitrate dehydrogenase, NADP-dependent C. reinhardtii 78.8 405
NP_175836.1 isocitrate dehydrogenase A. thaliana 78.5 409
NP_010217.1 isocitrate dehydrogenase (NADP(+)) IDP1 S. cerevisiae 75.5 416
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_002712664.1 PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble O. cuniculus 99.0 413
XP_536047.2 PREDICTED: isocitrate dehydrogenase [NADP] cytoplasmic isoform 1 C. lupus familiaris 98.5 413

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; liver; testis; embryonic tissue; prostate; skin; intestine; uncharacterized tissue; uterus; umbilical cord; adrenal gland; kidney; mixed; ovary; lymph; placenta; trachea; thymus; stomach; ascites; lung; mouth; vascular; connective tissue; blood; pancreas; mammary gland; pharynx; esophagus; bone marrow; bladder; eye; spleen; heart; pituitary gland; cervix; adipose tissue; bone; muscle; larynx; nerve; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q33.3
UniSTS entry: Chr 2 RH47131
UniSTS entry: Chr 2 G43665
UniSTS entry: Chr 2 G30308
UniSTS entry: Chr 2 SHGC-2545
UniSTS entry: Chr 2 RH81021
UniSTS entry: Chr 2 RH41922 [Map Viewer]
UniSTS entry: Chr 1 PMC156606P3
UniSTS entry: Chr 1 D7S3207
UniSTS entry: Chr 1 PMC156606P4
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AF020038.1 Homo sapiens NADP-dependent isocitrate dehydrogenase (IDH) mRNA, complete cds PA
BX537411.1 Homo sapiens mRNA; cDNA DKFZp686M0959 (from clone DKFZp686M0959); complete cds PA
AK125247.1 Homo sapiens cDNA FLJ43257 fis, clone HELAC2000301 A
NM_005896.2 Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble (IDH1), mRNA PA
AL136702.1 Homo sapiens mRNA; cDNA DKFZp566J151 (from clone DKFZp566J151) PA
CR536499.1 Homo sapiens full open reading frame cDNA clone RZPDo834C0620D for gene IDH1, isocitrate dehydrogenase 1 (NADP+), soluble; complete cds, incl. stopcodon P
CR533522.1 Homo sapiens full open reading frame cDNA clone RZPDo834C1219D for gene IDH1, isocitrate dehydrogenase 1 (NADP+), soluble; complete cds, incl. stopcodon P
CR541695.1 Homo sapiens full open reading frame cDNA clone RZPDo834G0228D for gene IDH1, isocitrate dehydrogenase 1 (NADP+), soluble; complete cds, without stopcodon P
AF113917.1 Homo sapiens NADP+-dependent isocitrate dehydrogenase (PICD) mRNA, complete cds P
BC093020.1 Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble, mRNA (cDNA clone MGC:110907 IMAGE:30528912), complete cds PA
BC012846.1 Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble, mRNA (cDNA clone MGC:21176 IMAGE:3880331), complete cds PA
AK312242.1 Homo sapiens cDNA, FLJ92536, highly similar to Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble (IDH1), mRNA P
AK302105.1 Homo sapiens cDNA FLJ57227 complete cds, highly similar to Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42) P
BC021046.1 Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble, mRNA (cDNA clone IMAGE:2966588) PA
U62389.1 Human putative cytosolic NADP-dependent isocitrate dehydrogenase mRNA, partial cds P

EST sequences (10 of 834) [Show all sequences]

AA904568.1 Clone IMAGE:1524610 mixed 3' read A
CB044359.1 Clone IMAGE:3217451 intestine 3' read A
CB044360.1 Clone IMAGE:3217451 intestine 5' read P
BX118032.1 Clone IMAGp998F23576_;_IMAGE:263446 skin P
AI208914.1 Clone IMAGE:1839534 testis 3' read A
AI215591.1 Clone IMAGE:1845018 mixed 3' read A
AI263053.1 Clone IMAGE:2028313 kidney 3' read A
CB146002.1 Clone L16HLK3-13-A09 liver 5' read P
CB156937.1 Clone L17N670205n1-6-A09 liver 5' read
CB156132.1 Clone L18POOL1n1-2-A03 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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