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UGID:2061139     UniGene Hs.592128     Homo sapiens (human)   FBXW10
F-box and WD repeat domain containing 10 (FBXW10)

Human protein-coding gene FBXW10. Represented by 42 ESTs from 14 cDNA libraries. EST representation biased toward testis. Corresponds to 3 reference sequences (different isoforms). [UniGene 2061139 - Hs.592128]

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001254514.1 FBXW10 gene product H. sapiens 100.0 1051
NP_001028841.2 Fbxw10 gene product M. musculus 74.0 1019
XP_692449.3 PREDICTED: f-box/WD repeat-containing protein 10-like D. rerio 51.6 155
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
XP_003318143.1 PREDICTED: LOW QUALITY PROTEIN: CMT1A duplicated region transcript 1 protein P. troglodytes 98.1 669
XP_003912427.1 PREDICTED: F-box/WD repeat-containing protein 10 P. anubis 94.2 901

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: testis [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; uncharacterized tissue; brain; mixed; placenta
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p12
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AY729024.1 Homo sapiens ubiquitin ligase specificity factor (FBXW10) mRNA, complete cds, alternatively spliced P
AL136822.1 Homo sapiens mRNA; cDNA DKFZp434O1826 (from clone DKFZp434O1826) PA
AK310383.1 Homo sapiens cDNA, FLJ17425 P
NM_001267586.1 Homo sapiens F-box and WD repeat domain containing 10 (FBXW10), transcript variant 2, mRNA PA
NM_001267585.1 Homo sapiens F-box and WD repeat domain containing 10 (FBXW10), transcript variant 1, mRNA PA
NR_051988.1 Homo sapiens F-box and WD repeat domain containing 10 (FBXW10), transcript variant 3, non-coding RNA PA

EST sequences (10 of 42) [Show all sequences]

AI809214.1 Clone IMAGE:2360829 mixed 3' read PA
CF994774.1 Clone IMAGE:30531416 placenta 5' read P
CV024278.1 mixed 5' read P
BP369886.1 Clone TST03690 testis 5' read P
BE502292.1 Clone IMAGE:3197385 uncharacterized tissue 3' read
AV721196.2 Clone HTBBBB06 brain 5' read
DB038001.1 Clone TESTI2024157 testis 5' read P
DB067549.1 Clone TESTI4009210 testis 5' read P
DB080156.1 Clone TESTI4025590 testis 5' read P
DB074227.1 Clone TESTI4017786 testis 5' read P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

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