> STE20-like kinase (SLK)
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UGID:2060933     UniGene Hs.591922     Homo sapiens (human)   SLK Order cDNA clone, Links
STE20-like kinase (SLK)

Human protein-coding gene SLK. Represented by 281 ESTs from 168 cDNA libraries. Corresponds to reference sequence NM_014720.2. [UniGene 2060933 - Hs.591922]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055535.2 SLK gene product H. sapiens 100.0 1234
XP_508017.2 PREDICTED: STE20-like kinase isoform 5 P. troglodytes 99.8 1235
NP_033315.2 Slk gene product M. musculus 93.8 1232
NP_001139073.1 STE20-like serine/threonine-protein kinase D. rerio 80.0 1200
NP_001079164.1 serine/threonine-protein kinase 10-A X. laevis 68.2 946
NP_611908.2 Sterile20-like kinase, isoform A D. melanogaster 56.4 1293
NP_001077708.1 map 4 kinase alpha1 A. thaliana 49.4 247
XP_001700998.1 mitogen activated protein kinase kinase kinase kinase 1 C. reinhardtii 49.0 191
XP_964928.2 hypothetical protein NCU00772 N. crassa 47.8 180
NP_001041219.2 Protein CST-2 C. elegans 47.7 218
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_003904270.1 PREDICTED: STE20-like serine/threonine-protein kinase isoform 2 P. anubis 99.1 1235
XP_001114162.1 PREDICTED: STE20-like serine/threonine-protein kinase-like isoform 2 M. mulatta 99.0 1235

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; kidney; ear; placenta; uncharacterized tissue; prostate; brain; testis; uterus; mixed; mammary gland; intestine; embryonic tissue; adipose tissue; pancreas; vascular; liver; muscle; lymph node; ovary; umbilical cord; larynx; trachea; skin; stomach; bladder; eye; blood; adrenal gland; spinal cord; connective tissue; esophagus; cervix; heart; pharynx; ascites; bone marrow; spleen; nerve; bone; parathyroid; thyroid; lymph
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q24.33
UniSTS entry: Chr 10 RH25417
UniSTS entry: Chr 10 SLK_8987
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BC047762.1 Homo sapiens STE20-like kinase (yeast), mRNA (cDNA clone IMAGE:5586698), partial cds PA
BC047885.1 Homo sapiens STE20-like kinase (yeast), mRNA (cDNA clone IMAGE:5534205), partial cds PA
BX648375.1 Homo sapiens mRNA; cDNA DKFZp686I03189 (from clone DKFZp686I03189) A
BC064804.1 Homo sapiens STE20-like kinase (yeast), mRNA (cDNA clone IMAGE:6504112), partial cds PA
NM_014720.2 Homo sapiens STE20-like kinase (SLK), mRNA PA
BC111565.1 Homo sapiens STE20-like kinase (yeast), mRNA (cDNA clone MGC:133067 IMAGE:40009070), complete cds P
AF273048.1 Homo sapiens CTCL tumor antigen se20-9 mRNA, complete cds PA
EF139853.1 Homo sapiens clone 1-3 STE20-related serine/threonine kinase splice variant (SLK) mRNA, partial sequence; alternatively spliced P
AK307389.1 Homo sapiens cDNA, FLJ97337 P
AK302855.1 Homo sapiens cDNA FLJ61681 partial cds, highly similar to STE20-like serine/threonine-protein kinase (EC2.7.11.1) P
D86959.1 Homo sapiens mRNA for KIAA0204 gene, partial cds P
BC008697.1 Homo sapiens STE20-like kinase (yeast), mRNA (cDNA clone IMAGE:3342723), with apparent retained intron PA
BC036736.1 Homo sapiens STE20-like kinase (yeast), mRNA (cDNA clone IMAGE:5521593), with apparent retained intron PA

EST sequences (10 of 281) [Show all sequences]

AA886401.1 Clone IMAGE:1500669 kidney 3' read
AA922539.1 Clone IMAGE:1551953 uncharacterized tissue 3' read A
AA928756.1 Clone IMAGE:1564697 mixed 3' read
AI052277.1 Clone IMAGE:1670059 brain 3' read
AI142750.1 Clone IMAGE:1634228 mixed 3' read
CB045363.1 Clone IMAGE:3218538 intestine 3' read A
CB045364.1 Clone IMAGE:3218538 intestine 5' read P
AI186648.1 Clone IMAGE:1725340 placenta 3' read
AI205999.1 Clone IMAGE:1759546 placenta 3' read
AI206000.1 Clone IMAGE:1759548 placenta 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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