> Major histocompatibility complex, class II, DQ alpha 1 (HLA-DQA1)
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UGID:2060809     UniGene Hs.591798     Homo sapiens (human)   HLA-DQA1 Links
Major histocompatibility complex, class II, DQ alpha 1 (HLA-DQA1)

Human protein-coding gene HLA-DQA1. Represented by 134 ESTs from 55 cDNA libraries. Corresponds to reference sequence NM_020056.4. [UniGene 2060809 - Hs.591798]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_064440.1 HLA-DQA2 gene product H. sapiens 100.0 254
NP_034508.2 H2-Aa gene product M. musculus 79.5 252
NP_001128546.1 uncharacterized protein LOC100189577 precursor X. laevis 52.9 244
Other hits (2 of 14) [Show all]SpeciesId(%)Len(aa)
XP_527354.1 PREDICTED: HLA class II histocompatibility antigen, DQ alpha 2 chain P. troglodytes 98.8 254
NP_001127767.1 MAMU-DQA1 gene product M. mulatta 95.7 254

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; lymph node; bone marrow; larynx; trachea; tonsil; mammary gland; mouth; cervix; uncharacterized tissue; kidney; blood; intestine; mixed; brain; heart; vascular; pharynx; pancreas; skin; parathyroid; stomach; uterus; muscle; lymph; ovary; testis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.3
UniSTS entry: RH78929
UniSTS entry: Chr 6 RH79899
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

M11124.1 Human MHC HLA DQ alpha-chain mRNA from DRw9 cell line P
DQ284439.1 Homo sapiens clone A6-DQA-43-T7 MHC class II antigen (HLA-DQA1) mRNA, HLA-DQA1*0302 allele, complete cds P
DQ284438.1 Homo sapiens clone A6-DQA-10-T7 MHC class II antigen (HLA-DQA1) mRNA, HLA-DQA1*0302 variant allele, complete cds P
DQ284437.1 Homo sapiens clone A6-DQA-5-T7 MHC class II antigen (HLA-DQA1) mRNA, HLA-DQA1*0302 variant allele, complete cds P
NM_020056.4 Homo sapiens major histocompatibility complex, class II, DQ alpha 2 (HLA-DQA2), mRNA P
AF533933.1 Homo sapiens MHC class II antigen (HLA-DQA1) mRNA, HLA-DQA1*0301 allele, partial cds
AF533926.1 Homo sapiens MHC class II antigen (HLA-DQA1) mRNA, HLA-DQA1*0301 allele, partial cds
AF533922.1 Homo sapiens MHC class II antigen (HLA-DQA1) mRNA, HLA-DQA1*0301 allele, partial cds
AF533916.1 Homo sapiens MHC class II antigen (HLA-DQA1) mRNA, HLA-DQA1*0301 allele, partial cds
AF533910.1 Homo sapiens MHC class II antigen (HLA-DQA1) mRNA, HLA-DQA1*0301 allele, partial cds
L34089.1 Human (clones DKB-82, YT-71) MHC class II HLA-DQA1*0302 mRNA, partial cds P
L34088.1 Human (clones 5, 9) MHC class II HLA-DQA1*03011 mRNA, partial cds P
M95728.1 H.sapiens MHC class II HLA-DQA2 mRNA, exon 2 P
M95727.1 H.sapiens MHC class II HLA-DQA2 mRNA, exon 2 P
J00199.1 human hla-dr heavy chain alloantigen dc1 mrna, 3' end P
L34352.1 Human (clones WL-3 and WL-8) leucocyte antigen DQA1 allele (HLA DQA1-0302) mRNA, partial cds P
JF895477.1 Homo sapiens isolate S0691-2208 MHC class II antigen (HLA-DQA1) mRNA, complete cds P

EST sequences (10 of 134) [Show all sequences]

AA978343.1 Clone IMAGE:1588788 kidney 3' read PA
AA977287.1 Clone IMAGE:1589968 kidney 3' read A
AA995292.1 Clone IMAGE:1606573 kidney 3' read PA
AI141141.1 Clone IMAGE:1739435 lung 3' read A
AI193894.1 Clone IMAGE:1745309 lung 3' read PA
AI203724.1 Clone IMAGE:1755928 lung 3' read A
AI340964.1 Clone IMAGE:1915027 kidney 3' read A
AI344688.1 Clone IMAGE:1917573 kidney 3' read PA
AI433194.1 Clone IMAGE:2132674 lymph node 3' read A
AI433246.1 Clone IMAGE:2133519 lymph node 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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