> Myelin protein zero (MPZ)
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UGID:2060497     UniGene Hs.591486     Homo sapiens (human)   MPZ Links
Myelin protein zero (MPZ)

Human protein-coding gene MPZ. Represented by 120 ESTs from 35 cDNA libraries. EST representation biased toward nerve; juvenile. Corresponds to reference sequence NM_000530.6. [UniGene 2060497 - Hs.591486]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000521.2 MPZ gene product H. sapiens 100.0 247
XP_001173975.1 PREDICTED: myelin protein P0 P. troglodytes 99.6 257
XP_001118030.1 PREDICTED: myelin protein P0-like M. mulatta 99.6 255
NP_032649.2 Mpz gene product M. musculus 96.4 247
NP_001091356.1 myelin protein P0 precursor X. laevis 65.1 237
NP_919342.1 mpz gene product D. rerio 53.7 202
Other hits (2 of 14) [Show all]SpeciesId(%)Len(aa)
XP_003893018.1 PREDICTED: myelin protein P0 P. anubis 98.4 255
XP_001925038.2 PREDICTED: myelin protein P0-like S. scrofa 98.4 246

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: nerve [show more like this]
juvenile [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; ganglia; nerve; thymus; skin; lymph node; uncharacterized tissue; embryonic tissue; mixed; testis; intestine; heart; muscle; prostate; blood; trachea; lung; ear; eye; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q23.3
UniSTS entry: Chr 1 GDB:453314
UniSTS entry: Chr 1 G15925
UniSTS entry: Chr 1 GDB:453316
UniSTS entry: Chr 1 GDB:567273
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

BT006765.1 Homo sapiens myelin protein zero (Charcot-Marie-Tooth neuropathy 1B) mRNA, complete cds P
NM_000530.6 Homo sapiens myelin protein zero (MPZ), mRNA PA
AK313555.1 Homo sapiens cDNA, FLJ94116, Homo sapiens myelin protein zero (Charcot-Marie-Tooth neuropathy1B) (MPZ), mRNA P
S66705.1 P0=28 kda major peripheral myelin protein [human, Charcot-Marie-Tooth disease type 1B patient, mRNA PartialMutant, 385 nt] P
D10537.1 Homo sapiens mRNA for major structural protein of myelin, complete cds P

EST sequences (10 of 120) [Show all sequences]

AI005369.1 Clone IMAGE:1624878 embryonic tissue 3' read A
BX090441.1 Clone IMAGp998M074121_;_IMAGE:1624878 embryonic tissue A
AI351956.1 Clone IMAGE:1933324 mixed 3' read A
BX354427.2 Clone CS0DC019YC04 uncharacterized tissue 5' read P
BX370296.2 Clone CS0DJ005YB08 blood 5' read
CD172001.1 Clone IMAGE:30375727 brain 5' read P
CD172093.1 Clone IMAGE:30377441 brain 5' read P
CD172164.1 Clone IMAGE:30375814 brain 5' read
CD172268.1 Clone IMAGE:30376004 brain 5' read
CD172418.1 Clone IMAGE:30377382 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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