> Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7)
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UGID:2060474     UniGene Hs.591463     Homo sapiens (human)   SMG7 Order cDNA clone, Links
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7)

Human protein-coding gene SMG7. Represented by 534 ESTs from 264 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 2060474 - Hs.591463]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_963863.2 SMG7 gene product H. sapiens 100.0 1177
XP_514048.3 PREDICTED: protein SMG7 P. troglodytes 100.0 1144
XP_001109289.2 PREDICTED: protein SMG7-like isoform 1 M. mulatta 99.8 1177
XP_003893460.1 PREDICTED: protein SMG7 isoform 4 P. anubis 99.8 1177
NP_001005507.1 Smg7 gene product M. musculus 97.0 1133
NP_001086379.1 smg-7 homolog, nonsense mediated mRNA decay factor X. laevis 80.2 1128
NP_001038548.2 smg7 gene product D. rerio 78.8 1129
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_003364994.1 PREDICTED: protein SMG7 isoform 3 E. caballus 98.6 1177
XP_003357623.2 PREDICTED: protein SMG7 isoform 4 S. scrofa 98.5 1168

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; pituitary gland; trachea; larynx; prostate; placenta; mixed; lymph node; liver; spleen; connective tissue; intestine; bone marrow; thyroid; skin; uterus; lung; kidney; blood; embryonic tissue; eye; cervix; pancreas; ovary; muscle; heart; bone; pharynx; mammary gland; mouth; adrenal gland; bladder; vascular; thymus; salivary gland; tonsil; ascites; lymph; stomach; ganglia; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q25
UniSTS entry: Chr 1 D1S3351 [Map Viewer]
UniSTS entry: Chr 1 AL009653
UniSTS entry: Chr 1 SHGC-75977 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

BC052565.1 Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), mRNA (cDNA clone IMAGE:6337867), partial cds PA
NM_201568.2 Homo sapiens smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 2, mRNA PA
NM_201569.2 Homo sapiens smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 4, mRNA PA
NM_173156.2 Homo sapiens smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 1, mRNA PA
AY386363.1 Homo sapiens breast cancer-associated antigen SGA-56M (SGA56M) mRNA, complete cds P
BC036381.1 Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), mRNA (cDNA clone MGC:33347 IMAGE:4829267), complete cds PA
AK056035.1 Homo sapiens cDNA FLJ31473 fis, clone NT2NE2001530 P
AK307394.1 Homo sapiens cDNA, FLJ97342 P
AK074297.1 Homo sapiens cDNA FLJ23717 fis, clone HEP13634 PA
AL833675.1 Homo sapiens mRNA; cDNA DKFZp667P0221 (from clone DKFZp667P0221) PA
AK299178.1 Homo sapiens cDNA FLJ61348 complete cds, highly similar to Protein SMG7 P
AK297207.1 Homo sapiens cDNA FLJ55570 partial cds, highly similar to Protein SMG7 P
AK091477.1 Homo sapiens cDNA FLJ34158 fis, clone FCBBF3013589, weakly similar to GLUTENIN, LOW MOLECULAR WEIGHT SUBUNIT PRECURSOR P
BC015788.1 Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), mRNA (cDNA clone IMAGE:4864144), with apparent retained intron PA
BC009281.2 Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), mRNA (cDNA clone IMAGE:4135126) PA
D87437.2 Homo sapiens mRNA for KIAA0250 gene, partial cds P
NM_001174061.1 Homo sapiens smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 5, mRNA PA
AB085674.1 Homo sapiens hsmg-7 mRNA for SMG-7, complete cds P

EST sequences (10 of 534) [Show all sequences]

AA976179.1 Clone IMAGE:1558489 lung 3' read P
R17534.1 Clone IMAGE:30875 brain 5' read
AI023200.1 Clone IMAGE:1643401 testis 3' read A
AI024200.1 Clone IMAGE:1643709 testis 3' read A
R18836.1 Clone IMAGE:33086 brain 5' read
AA928152.1 Clone IMAGE:1563579 mixed 3' read
AI057273.1 Clone IMAGE:1669661 brain 3' read A
AI074557.1 Clone IMAGE:1673175 mixed 3' read
R20883.1 Clone IMAGE:130066 placenta 5' read
AI089919.1 Clone IMAGE:1686918 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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