MYC binding protein 2, E3 ubiquitin protein ligase (MYCBP2)

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UGID:2060232 UniGene Hs.591221 Homo sapiens (human) MYCBP2

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MYC binding protein 2, E3 ubiquitin protein ligase (MYCBP2)

Human protein-coding gene MYCBP2. Represented by 483 ESTs from 238 cDNA libraries. Corresponds to reference sequence NM_015057.4. [UniGene 2060232 - Hs.591221]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_055872.4 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MYCBP2 gene product	H. sapiens	100.0	4677
XP_001140575.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: probable E3 ubiquitin-protein ligase MYCBP2 isoform 1	P. troglodytes	100.0	4676
XP_002800836.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: probable E3 ubiquitin-protein ligase MYCBP2-like	M. mulatta	99.7	4603
NP_997098.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Mycbp2 gene product	M. musculus	97.8	4745
NP_001012247.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	mycbp2 gene product	D. rerio	89.8	4573
NP_001087763.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MYC binding protein 2, E3 ubiquitin protein ligase	X. laevis	84.8	356
NP_505267.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein RPM-1	C. elegans	59.6	318
NP_511159.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	highwire	D. melanogaster	55.3	4625
Other hits (2 of 31) [Show all]		Species	Id(%)	Len(aa)
XP_003914008.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase MYCBP2, partial	P. anubis	99.4	4605
XP_857946.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: probable E3 ubiquitin-protein ligase MYCBP2 isoform 2	C. lupus familiaris	99.4	4677

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; mixed; uncharacterized tissue; embryonic tissue; pharynx; mammary gland; uterus; eye; lung; intestine; prostate; spleen; salivary gland; mouth; kidney; lymph node; pituitary gland; placenta; stomach; muscle; testis; vascular; thyroid; tonsil; connective tissue; heart; bone; liver; larynx; bone marrow; thymus; trachea; blood; esophagus; pancreas; skin; lymph; ovary; parathyroid; ascites; adipose tissue; nerve; ear; adrenal gland

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	13
Map position:	13q22
UniSTS entry:	Chr 13	WI-21663	[Map Viewer]
UniSTS entry:		MYCBP2

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AF075587.1	Homo sapiens protein associated with Myc mRNA, complete cds	PA
AB020723.1	Homo sapiens mRNA for KIAA0916 protein, partial cds	P
BX647202.1	Homo sapiens mRNA; cDNA DKFZp686M08244 (from clone DKFZp686M08244)	PA
NM_015057.4	Homo sapiens MYC binding protein 2, E3 ubiquitin protein ligase (MYCBP2), mRNA	PA
AK023888.1	Homo sapiens cDNA FLJ13826 fis, clone THYRO1000585, highly similar to Homo sapiens protein associated with Myc mRNA	P
AK025250.1	Homo sapiens cDNA: FLJ21597 fis, clone COL07126	PA
AK025299.1	Homo sapiens cDNA: FLJ21646 fis, clone COL08455	PA
AK000968.1	Homo sapiens cDNA FLJ10106 fis, clone HEMBA1002569, highly similar to Homo sapiens protein associated with Myc mRNA	P
AF083244.1	Homo sapiens HSPC026 mRNA, complete cds	PA
BC037971.2	Homo sapiens MYC binding protein 2, mRNA (cDNA clone IMAGE:4944770), partial cds	PA

EST sequences (10 of 483) [Show all sequences]

AI003360.1	Clone IMAGE:1629232	brain	3' read	P
R21869.1	Clone IMAGE:130459	placenta	3' read	A
R22388.1	Clone IMAGE:130516	placenta	5' read
AI167406.1	Clone IMAGE:1661618	mixed	3' read
BX093662.1	Clone IMAGp998K01373_;_IMAGE:195960	mixed		P
AI205089.1	Clone IMAGE:1684469	brain	3' read	P
AI278706.1	Clone IMAGE:1873387	intestine	3' read
AI290115.1	Clone IMAGE:1992662	uterus	3' read
AI288619.1	Clone IMAGE:1879386	mixed	3' read
AI366946.1	Clone IMAGE:1991440	uterus	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria