> Fibrillin 1 (FBN1)
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UGID:2060144     UniGene Hs.591133     Homo sapiens (human)   FBN1 Order cDNA clone, Links
Fibrillin 1 (FBN1)

Human protein-coding gene FBN1. Represented by 552 ESTs from 201 cDNA libraries. Corresponds to reference sequence NM_000138.4. [UniGene 2060144 - Hs.591133]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000129.3 FBN1 gene product H. sapiens 100.0 2870
XP_001149266.3 PREDICTED: LOW QUALITY PROTEIN: fibrillin-1 P. troglodytes 100.0 3020
XP_003900950.1 PREDICTED: fibrillin-1 P. anubis 99.9 2870
XP_001113107.2 PREDICTED: fibrillin-1-like M. mulatta 99.8 3013
NP_032019.2 Fbn1 gene product M. musculus 97.8 2872
NP_001129262.1 fbn2b gene product D. rerio 75.3 2834
NP_001082254.1 latent transforming growth factor beta binding protein 1 precursor X. laevis 48.5 361
NP_001245870.1 dumpy, isoform D D. melanogaster 46.4 192
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
NP_776478.1 FBN1 gene product B. taurus 98.8 2870
XP_861706.2 PREDICTED: fibrillin-1 isoform 3 C. lupus familiaris 98.6 2870

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; mixed; ascites; stomach; connective tissue; embryonic tissue; bone; trachea; mammary gland; testis; esophagus; uterus; larynx; thymus; kidney; brain; heart; adrenal gland; prostate; amniotic fluid; uncharacterized tissue; eye; skin; muscle; umbilical cord; vascular; lung; intestine; liver; ovary; spleen; pancreas; adipose tissue; mouth; bladder; pharynx; thyroid; lymph node; salivary gland; nerve; ear; ganglia; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q21.1
UniSTS entry: Chr 15 D15S1255
UniSTS entry: Chr 15 WI-18561 [Map Viewer]
UniSTS entry: Chr 15 GDB:455176
UniSTS entry: Chr 15 GDB:190048
UniSTS entry: Chr 15 RH45122
UniSTS entry: Chr 15 GDB:190047
UniSTS entry: Chr 15 GDB:455155
UniSTS entry: Chr 15 SHGC-56864
UniSTS entry: Chr 15 GDB:438900
UniSTS entry: Chr 15 GDB:636540
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

L13923.1 Homo sapiens fibrillin mRNA, complete cds P
NM_000138.4 Homo sapiens fibrillin 1 (FBN1), mRNA PA
AB208840.1 Homo sapiens mRNA for fibrillin 1 variant protein P
X63556.1 H.sapiens mRNA for fibrillin PA
AK309616.1 Homo sapiens cDNA, FLJ99657 P
BC146854.1 Homo sapiens fibrillin 1, mRNA (cDNA clone MGC:181957 IMAGE:9056782), complete cds P
AK304737.1 Homo sapiens cDNA FLJ61597 partial cds, highly similar to Fibrillin-1 precursor P
X62008.1 Homo sapiens partial mRNA for fibrillin 15 P

EST sequences (10 of 552) [Show all sequences]

AA911184.1 Clone IMAGE:1520351 kidney 3' read A
AI057487.1 Clone IMAGE:1653157 mixed 3' read
AI078625.1 Clone IMAGE:1659823 embryonic tissue 3' read
AI081314.1 Clone IMAGE:1661891 mixed 3' read P
AI090214.1 Clone IMAGE:1696673 uterus 3' read P
AI092375.1 Clone IMAGE:1689014 mixed 3' read P
AI097173.1 Clone IMAGE:1707284 heart 3' read A
AI127621.1 Clone IMAGE:1711142 uterus 3' read A
AI128206.1 Clone IMAGE:1712796 uterus 3' read P
AI139967.1 Clone IMAGE:1689874 mixed 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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