> Isocitrate dehydrogenase 3 (NAD+) alpha (IDH3A)
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UGID:2060121     UniGene Hs.591110     Homo sapiens (human)   IDH3A Order cDNA clone, Links
Isocitrate dehydrogenase 3 (NAD+) alpha (IDH3A)

Human protein-coding gene IDH3A. Represented by 763 ESTs from 281 cDNA libraries. Corresponds to reference sequence NM_005530.2. [UniGene 2060121 - Hs.591110]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001106839.2 PREDICTED: isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 M. mulatta 100.0 365
XP_510524.3 PREDICTED: isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 8 P. troglodytes 100.0 365
NP_005521.1 IDH3A gene product H. sapiens 100.0 365
XP_001492522.3 PREDICTED: isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial-like E. caballus 99.7 315
NP_083849.1 Idh3a gene product M. musculus 98.9 365
NP_957245.2 idh3a gene product D. rerio 93.7 361
NP_001085990.1 isocitrate dehydrogenase 3 (NAD+) alpha X. laevis 92.9 366
NP_492330.2 Protein IDHA-1 C. elegans 79.9 352
NP_573388.1 lethal (1) G0156, isoform A D. melanogaster 78.0 340
XP_962283.1 isocitrate dehydrogenase subunit 2, mitochondrial precursor N. crassa 67.7 340
XP_001694857.1 isocitrate dehydrogenase, NAD-dependent C. reinhardtii 67.7 352
NP_568113.1 Isocitrate dehydrogenase [NAD] catalytic subunit 5 A. thaliana 64.5 358
NP_014779.1 isocitrate dehydrogenase (NAD(+)) IDH2 S. cerevisiae 61.1 341
Other hits (2 of 58) [Show all]SpeciesId(%)Len(aa)
XP_003919634.1 PREDICTED: LOW QUALITY PROTEIN: isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial P. anubis 99.2 387
NP_446090.1 Idh3a gene product R. norvegicus 99.2 365

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; kidney; uterus; mixed; testis; placenta; thymus; skin; prostate; heart; mammary gland; pituitary gland; pharynx; liver; lymph; lung; uncharacterized tissue; mouth; cervix; eye; vascular; embryonic tissue; connective tissue; thyroid; umbilical cord; salivary gland; adrenal gland; esophagus; spleen; lymph node; trachea; blood; stomach; pancreas; bladder; ascites; muscle; bone; ovary; larynx; tonsil; parathyroid; adipose tissue; nerve; pineal gland; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q25.1-q25.2
UniSTS entry: Chr 15 RH64913
UniSTS entry: Chr 15 D15S1087 [Map Viewer]
UniSTS entry: Chr 15 STS-U07681 [Map Viewer]
UniSTS entry: Chr 1 D17S610
UniSTS entry: Chr 1 D8S2279
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AK123316.1 Homo sapiens cDNA FLJ41322 fis, clone BRAMY2045530
NM_005530.2 Homo sapiens isocitrate dehydrogenase 3 (NAD+) alpha (IDH3A), nuclear gene encoding mitochondrial protein, mRNA PA
CR749548.1 Homo sapiens mRNA; cDNA DKFZp686A08194 (from clone DKFZp686A08194) PA
AK222973.1 Homo sapiens mRNA for isocitrate dehydrogenase 3 (NAD+) alpha precursor variant, clone: HSI02474 P
AL442090.1 Homo sapiens mRNA; cDNA DKFZp761L1216 (from clone DKFZp761L1216) PA
U07681.1 Human NAD(H)-specific isocitrate dehydrogenase alpha subunit precursor mRNA, complete cds P
BC021967.2 Homo sapiens isocitrate dehydrogenase 3 (NAD+) alpha, mRNA (cDNA clone MGC:1406 IMAGE:2989636), complete cds PA
AK096721.1 Homo sapiens cDNA FLJ39402 fis, clone PLACE6011975
AK093531.1 Homo sapiens cDNA FLJ36212 fis, clone THYMU2000602, highly similar to ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL PRECURSOR (EC 1.1.1.41) P
AK299970.1 Homo sapiens cDNA FLJ52894 complete cds, highly similar to Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) P
AK296002.1 Homo sapiens cDNA FLJ55931 complete cds, highly similar to Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) P
AL110096.1 Homo sapiens EST from clone 501821, 5' end P
AK316051.1 Homo sapiens cDNA, FLJ78950 complete cds, highly similar to Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) P
AK315963.1 Homo sapiens cDNA, FLJ78862 complete cds, highly similar to Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor (EC 1.1.1.41) P
BC036227.1 Homo sapiens isocitrate dehydrogenase 3 (NAD+) alpha, mRNA (cDNA clone IMAGE:5274718) PA

EST sequences (10 of 763) [Show all sequences]

AI003939.1 Clone IMAGE:1624404 embryonic tissue 3' read A
AI027931.1 Clone IMAGE:1645509 testis 3' read A
AA947090.1 Clone IMAGE:1561938 mixed 3' read A
AI033229.1 Clone IMAGE:1654858 mixed 3' read A
AI042572.1 Clone IMAGE:1665820 skin 3' read A
AI089248.1 Clone IMAGE:1695732 uterus 3' read A
AI095654.1 Clone IMAGE:1697726 uterus 3' read A
AI097151.1 Clone IMAGE:1707256 heart 3' read A
R22552.1 Clone IMAGE:130625 placenta 5' read
AI168600.1 Clone IMAGE:1656032 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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