> Structural maintenance of chromosomes 4 (SMC4)
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UGID:138578     UniGene Hs.58992     Homo sapiens (human)   SMC4 Links
Structural maintenance of chromosomes 4 (SMC4)

Human protein-coding gene SMC4. Represented by 535 ESTs from 224 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 138578 - Hs.58992]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001002800.1 SMC4 gene product H. sapiens 100.0 1287
XP_001158064.1 PREDICTED: structural maintenance of chromosomes protein 4 isoform 14 P. troglodytes 99.9 1287
NP_598547.1 structural maintenance of chromosomes protein 4 M. musculus 94.7 1285
NP_001081371.1 structural maintenance of chromosomes protein 4 X. laevis 86.8 1284
NP_775360.1 smc4 gene product D. rerio 79.5 1286
XP_001700568.1 structural maintenance of chromosomes protein 4 C. reinhardtii 61.7 1224
NP_199671.1 structural maintenance of chromosomes protein 4 A. thaliana 61.3 1234
XP_958567.2 hypothetical protein NCU09063 N. crassa 60.4 1362
NP_723996.1 gluon D. melanogaster 59.8 1299
NP_013187.1 condensin subunit SMC4 S. cerevisiae 58.6 1265
NP_497935.1 Protein SMC-4 C. elegans 57.7 1362
Other hits (2 of 61) [Show all]SpeciesId(%)Len(aa)
XP_001098806.2 PREDICTED: structural maintenance of chromosomes protein 4-like isoform 8 M. mulatta 99.3 1286
XP_003894934.1 PREDICTED: structural maintenance of chromosomes protein 4 isoform 1 P. anubis 99.3 1286

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; embryonic tissue; uncharacterized tissue; lymph node; uterus; brain; liver; thymus; thyroid; ear; mouth; cervix; pituitary gland; umbilical cord; placenta; mammary gland; kidney; skin; lung; pancreas; spleen; heart; esophagus; adrenal gland; trachea; bladder; mixed; ovary; bone marrow; larynx; prostate; blood; salivary gland; lymph; ascites; intestine; bone; stomach; eye; connective tissue; muscle; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3q26.1
UniSTS entry: Chr 3 STS-W93650
UniSTS entry: Chr 3 RH98841
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

AF092564.1 Homo sapiens chromosome-associated protein-C (hCAP-C) mRNA, partial cds P
AB019987.1 Homo sapiens hCAP-C mRNA for chromosome-associated polypeptide-C, complete cds P
AK128143.1 Homo sapiens cDNA FLJ46264 fis, clone TESTI4026080, highly similar to Structural maintenance of chromosomes 4-like 1 protein P
AK122939.1 Homo sapiens cDNA FLJ16648 fis, clone TESTI4035508, highly similar to Structural maintenance of chromosomes 4-like 1 protein P
NM_005496.3 Homo sapiens structural maintenance of chromosomes 4 (SMC4), transcript variant 1, mRNA PA
BC065259.1 Homo sapiens structural maintenance of chromosomes 4, mRNA (cDNA clone IMAGE:6145405), partial cds PA
AK002200.1 Homo sapiens cDNA FLJ11338 fis, clone PLACE1010720, highly similar to Homo sapiens mRNA for chromosome-associated polypeptide-C P
AL136877.1 Homo sapiens mRNA; cDNA DKFZp434F205 (from clone DKFZp434F205) PA
BC070161.1 Homo sapiens structural maintenance of chromosomes 4, mRNA (cDNA clone IMAGE:4252738), partial cds PA
NM_001002800.1 Homo sapiens structural maintenance of chromosomes 4 (SMC4), transcript variant 2, mRNA PA
AK026361.1 Homo sapiens cDNA: FLJ22708 fis, clone HSI13291 A
BC106033.1 Homo sapiens structural maintenance of chromosomes 4, mRNA (cDNA clone IMAGE:4996934), partial cds PA
AK225437.1 Homo sapiens mRNA for SMC4L1 protein variant, clone: HRC12916 PA
AK315070.1 Homo sapiens cDNA, FLJ96024 P
AK307508.1 Homo sapiens cDNA, FLJ97456 P
AL833949.1 Homo sapiens mRNA; cDNA DKFZp434N2050 (from clone DKFZp434N2050) PA
BC001557.1 Homo sapiens structural maintenance of chromosomes 4, mRNA (cDNA clone IMAGE:3460137), partial cds PA

EST sequences (10 of 535) [Show all sequences]

AA905562.1 Clone IMAGE:1506237 mixed 3' read A
AA992273.1 Clone IMAGE:1620428 testis 3' read PA
AA993325.1 Clone IMAGE:1618238 testis 3' read A
AI039965.1 Clone IMAGE:1659709 embryonic tissue 3' read A
AI073463.1 Clone IMAGE:1640238 testis 3' read P
AI138752.1 Clone IMAGE:1737515 testis 3' read P
AI146714.1 Clone IMAGE:1707534 heart 3' read PA
BX096199.1 Clone IMAGp998B111962_;_IMAGE:795562 testis P
AI168470.1 Clone IMAGE:1565805 mixed 3' read A
AI251019.1 Clone IMAGE:2004727 pancreas 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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