> FANCD2/FANCI-associated nuclease 1 (FAN1)
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UGID:1953652     UniGene Hs.584863     Homo sapiens (human)   FAN1 Order cDNA clone, Links
FANCD2/FANCI-associated nuclease 1 (FAN1)

Human protein-coding gene FAN1. Represented by 191 ESTs from 117 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 1953652 - Hs.584863]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055782.3 FAN1 gene product H. sapiens 100.0 1016
NP_808561.2 Fan1 gene product M. musculus 80.9 1019
NP_001084571.1 myotubularin-related protein 10-B X. laevis 64.0 175
NP_001038546.2 fan1 gene product D. rerio 57.6 966
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_510266.2 PREDICTED: fanconi-associated nuclease 1 isoform 3 P. troglodytes 99.3 1016
XP_003900750.1 PREDICTED: fanconi-associated nuclease 1 P. anubis 96.8 1015

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; lung; kidney; uncharacterized tissue; embryonic tissue; stomach; connective tissue; pharynx; eye; pancreas; nerve; uterus; prostate; liver; ovary; intestine; skin; placenta; thyroid; thymus; trachea; testis; adipose tissue; heart; muscle; mammary gland; adrenal gland; salivary gland; bone marrow; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q13.2-q13.3
UniSTS entry: Chr 15 RH64897
UniSTS entry: Chr 15 WI-19599 [Map Viewer]
UniSTS entry: Chr 15 WI-11934 [Map Viewer]
UniSTS entry: Chr 15 SHGC-58554
UniSTS entry: Chr 1 D13S1553
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BC044890.1 Homo sapiens myotubularin related protein 15, mRNA (cDNA clone IMAGE:3862786), with apparent retained intron PA
BC047882.1 Homo sapiens myotubularin related protein 15, mRNA (cDNA clone MGC:57620 IMAGE:5209981), complete cds PA
AB023235.2 Homo sapiens mRNA for KIAA1018 protein, partial cds P
BX647391.1 Homo sapiens mRNA; cDNA DKFZp686H21144 (from clone DKFZp686H21144) PA
NM_014967.4 Homo sapiens FANCD2/FANCI-associated nuclease 1 (FAN1), transcript variant 1, mRNA PA
CR936734.1 Homo sapiens mRNA; cDNA DKFZp686K16147 (from clone DKFZp686K16147) PA
CR936727.1 Homo sapiens mRNA; cDNA DKFZp451H236 (from clone DKFZp451H236) PA
AK290987.1 Homo sapiens cDNA FLJ77483 complete cds P
NM_001146096.1 Homo sapiens FANCD2/FANCI-associated nuclease 1 (FAN1), transcript variant 4, mRNA PA
NM_001146095.1 Homo sapiens FANCD2/FANCI-associated nuclease 1 (FAN1), transcript variant 3, mRNA PA
NM_001146094.1 Homo sapiens FANCD2/FANCI-associated nuclease 1 (FAN1), transcript variant 2, mRNA PA
HM560957.1 Homo sapiens fanconi anemia associated nuclease 1 (FAN1) mRNA, complete cds P

EST sequences (10 of 191) [Show all sequences]

AA923587.1 Clone IMAGE:1527237 mixed 3' read A
AA947151.1 Clone IMAGE:1553405 kidney 3' read A
AI125208.1 Clone IMAGE:1736889 testis 3' read A
BX100498.1 Clone IMAGp998I16188_;_IMAGE:133719 placenta P
R25547.1 Clone IMAGE:36597 brain 5' read
R27768.1 Clone IMAGE:133719 placenta 3' read A
R27851.1 Clone IMAGE:133719 placenta 5' read
AI250749.1 Clone IMAGE:1858542 mixed 3' read A
CB156850.1 Clone L17N670205n1-4-H05 liver 5' read
CB161773.1 Clone L17N670205n1-51-G12 liver 5' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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