> Thymine-DNA glycosylase (TDG)
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UGID:1953598     UniGene Hs.584809     Homo sapiens (human)   TDG Order cDNA clone, Links
Thymine-DNA glycosylase (TDG)

Human protein-coding gene TDG. Represented by 312 ESTs from 163 cDNA libraries. Corresponds to reference sequence NM_003211.4. [UniGene 1953598 - Hs.584809]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003202.3 TDG gene product H. sapiens 100.0 409
XP_509324.3 PREDICTED: G/T mismatch-specific thymine DNA glycosylase isoform 2 P. troglodytes 99.8 409
NP_766140.2 Tdg gene product M. musculus 96.2 420
NP_001084290.1 thymine-DNA glycosylase X. laevis 81.1 439
NP_001018587.1 tdg gene product D. rerio 70.3 427
NP_651925.1 Thd1, isoform A D. melanogaster 59.8 251
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
XP_001096295.1 PREDICTED: g/T mismatch-specific thymine DNA glycosylase isoform 2 M. mulatta 99.3 409
XP_003907115.1 PREDICTED: G/T mismatch-specific thymine DNA glycosylase isoform 1 P. anubis 99.3 409

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; pancreas; thyroid; pharynx; bladder; mammary gland; muscle; ovary; testis; mixed; uncharacterized tissue; placenta; mouth; thymus; liver; intestine; kidney; prostate; eye; bone marrow; heart; uterus; blood; pituitary gland; lung; lymph node; connective tissue; vascular; spleen; trachea; larynx; skin; esophagus; epididymis; lymph; parathyroid; stomach; adrenal gland; bone; cervix; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q24.1
UniSTS entry: Chr 12 GDB:451803
UniSTS entry: Chr 12 RH48085
UniSTS entry: Chr 12 RH70430
UniSTS entry: Chr 12 RH76675
UniSTS entry: Chr 12 RH98792
UniSTS entry: RH36631
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_003211.4 Homo sapiens thymine-DNA glycosylase (TDG), mRNA PA
BC071714.1 Homo sapiens cDNA clone IMAGE:4416064, containing frame-shift errors PA
BC104477.1 Homo sapiens thymine-DNA glycosylase, mRNA (cDNA clone IMAGE:6605225), partial cds PA
DQ786320.1 Homo sapiens clone HLS_IMAGE_823614 mRNA sequence A
AK311673.1 Homo sapiens cDNA, FLJ18715 P
AK313234.1 Homo sapiens cDNA, FLJ93738, highly similar to Homo sapiens thymine-DNA glycosylase (TDG), mRNA P
AK309792.1 Homo sapiens cDNA, FLJ99833 P
AK299832.1 Homo sapiens cDNA FLJ59972 complete cds, highly similar to G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.-) P
AK303631.1 Homo sapiens cDNA FLJ50939 complete cds, highly similar to G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.-) P
AK295387.1 Homo sapiens cDNA FLJ60553 complete cds, highly similar to G/T mismatch-specific thymine DNA glycosylase(EC 3.2.2.-) P
BC001307.1 Homo sapiens thymine-DNA glycosylase, mRNA (cDNA clone IMAGE:3452804) A
BC019925.1 Homo sapiens thymine-DNA glycosylase, mRNA (cDNA clone IMAGE:3881825), partial cds PA
BC010945.1 Homo sapiens thymine-DNA glycosylase, mRNA (cDNA clone IMAGE:4273393), with apparent retained intron PA
BC037557.1 Homo sapiens thymine-DNA glycosylase, mRNA (cDNA clone MGC:40342 IMAGE:5184772), complete cds PA

Model sequences (1)

XR_133016.3 PREDICTED: Homo sapiens G/T mismatch-specific thymine DNA glycosylase-like (LOC732360), misc_RNA P

EST sequences (10 of 312) [Show all sequences]

AI004247.1 Clone IMAGE:1625248 embryonic tissue 3' read A
AI016776.1 Clone IMAGE:1638908 testis 3' read A
AI056988.1 Clone IMAGE:1674507 mixed 3' read A
AI140385.1 Clone IMAGE:1692500 heart 3' read
CB047649.1 Clone IMAGE:3253215 kidney 3' read A
CB047650.1 Clone IMAGE:3253215 kidney 5' read A
BX114313.1 Clone IMAGp998C20148_;_IMAGE:30075 brain A
AI217316.1 Clone IMAGE:1844678 mixed 3' read A
AI266601.1 Clone IMAGE:1899654 kidney 3' read A
CB158281.1 Clone L18POOL1n1-10-C02 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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