> Guanine nucleotide binding protein (G protein), alpha z polypeptide (GNAZ)
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UGID:1953549     UniGene Hs.584760     Homo sapiens (human)   GNAZ
Guanine nucleotide binding protein (G protein), alpha z polypeptide (GNAZ)

Human protein-coding gene GNAZ. Represented by 199 ESTs from 84 cDNA libraries. Corresponds to reference sequence NM_002073.2. [UniGene 1953549 - Hs.584760]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001092181.1 PREDICTED: guanine nucleotide-binding protein G(z) subunit alpha isoform 1 M. mulatta 100.0 354
XP_003905358.1 PREDICTED: guanine nucleotide-binding protein G(z) subunit alpha isoform 1 P. anubis 100.0 354
XP_515016.2 PREDICTED: guanine nucleotide-binding protein G(z) subunit alpha P. troglodytes 100.0 354
NP_002064.1 GNAZ gene product H. sapiens 100.0 354
XP_848605.1 PREDICTED: guanine nucleotide-binding protein G(z) subunit alpha C. lupus familiaris 100.0 354
XP_002722595.1 PREDICTED: guanine nucleotide-binding protein G(z) subunit alpha-like O. cuniculus 99.7 354
NP_034441.1 Gnaz gene product M. musculus 98.9 354
NP_001084365.1 guanine nucleotide-binding protein G(i) subunit alpha-1 X. laevis 75.1 353
NP_957265.1 gnai1 gene product D. rerio 74.2 353
NP_477502.1 G protein alphai subunit 65A D. melanogaster 70.1 354
NP_492108.1 Protein GOA-1 C. elegans 68.3 353
XP_957133.1 guanine nucleotide-binding protein alpha subunit N. crassa 55.7 352
NP_011868.1 Gpa1p S. cerevisiae 51.6 254
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_001488491.1 PREDICTED: guanine nucleotide-binding protein G(z) subunit alpha-like E. caballus 99.4 354
NP_037321.1 Gnaz gene product R. norvegicus 98.9 354

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; eye; pancreas; ganglia; liver; testis; prostate; mixed; mammary gland; lung; bone; embryonic tissue; kidney; placenta; ovary; connective tissue; nerve; lymph node; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q11.22
UniSTS entry: Chr 22 RH1696
UniSTS entry: Chr 22 SHGC-7743
UniSTS entry: Chr 22 WI-14102 [Map Viewer]
UniSTS entry: Chr 22 G15854
UniSTS entry: Chr 22 GDB:452621
UniSTS entry: Chr 22 GNAZ
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_002073.2 Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide (GNAZ), mRNA PA
CR456495.1 Homo sapiens GNAZ full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.GNAZ.V4) P
BC078163.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide, mRNA (cDNA clone MGC:88028 IMAGE:6180193), complete cds PA
J03260.1 Human transducin alpha-subunit (GNAZ) mRNA, complete cds P
BC096828.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide, mRNA (cDNA clone MGC:111695 IMAGE:6519151), complete cds P
AK312519.1 Homo sapiens cDNA, FLJ92884, Homo sapiens guanine nucleotide binding protein (G protein), alphaz polypeptide (GNAZ), mRNA P
AK309397.1 Homo sapiens cDNA, FLJ99438 P
AF493899.1 Homo sapiens guanine nucleotide binding protein alpha z (GNAZ) mRNA, complete cds P
BC026342.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide, mRNA (cDNA clone MGC:26547 IMAGE:4814858), complete cds PA
AK293653.1 Homo sapiens cDNA FLJ51798 complete cds, highly similar to Guanine nucleotide-binding protein G(z) subunit alpha P
BC037333.1 Homo sapiens guanine nucleotide binding protein (G protein), alpha z polypeptide, mRNA (cDNA clone MGC:43258 IMAGE:5264642), complete cds PA

EST sequences (10 of 199) [Show all sequences]

AA983439.1 Clone IMAGE:1591572 kidney 3' read A
AA991805.1 Clone IMAGE:1623887 embryonic tissue 3' read A
AA994507.1 Clone IMAGE:1628896 mixed 3' read A
AA995249.1 Clone IMAGE:1626541 mixed 3' read
T05755.1 Clone HFBDF85 brain
AI018126.1 Clone IMAGE:1626324 mixed 3' read A
BX100782.1 Clone IMAGp998I06172_;_IMAGE:40773 brain
AI288502.1 Clone IMAGE:1879143 mixed 3' read A
CB218185.1 Clone IMAGE:5795336 bone 3' read
CB218186.1 Clone IMAGE:5795336 bone 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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