> ADAM metallopeptidase domain 10 (ADAM10)
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UGID:1851495     UniGene Hs.578508     Homo sapiens (human)   ADAM10 Order cDNA clone, Links
ADAM metallopeptidase domain 10 (ADAM10)

Human protein-coding gene ADAM10. Represented by 422 ESTs from 169 cDNA libraries. Corresponds to reference sequence NM_001110.2. [UniGene 1851495 - Hs.578508]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001097016.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 isoform 5 M. mulatta 100.0 747
XP_003901039.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 P. anubis 100.0 747
XP_001172405.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 isoform 4 P. troglodytes 100.0 747
NP_001101.1 ADAM10 gene product H. sapiens 100.0 747
NP_031425.2 Adam10 gene product M. musculus 98.4 748
NP_001083912.1 disintegrin and metalloproteinase domain-containing protein 10 precursor X. laevis 89.6 748
NP_001152786.1 disintegrin and metalloproteinase domain-containing protein 10 precursor D. rerio 84.7 750
NP_001014481.1 kuzbanian, isoform C D. melanogaster 53.4 556
NP_492377.1 Protein SUP-17 C. elegans 50.8 384
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_002718256.1 PREDICTED: ADAM metallopeptidase domain 10 O. cuniculus 99.3 741
XP_001498219.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 E. caballus 98.8 733

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; eye; esophagus; stomach; mouth; thymus; testis; placenta; connective tissue; skin; uncharacterized tissue; liver; mammary gland; ovary; thyroid; vascular; embryonic tissue; trachea; muscle; uterus; intestine; spleen; umbilical cord; bladder; ascites; lung; heart; prostate; larynx; kidney; lymph node; blood; pancreas; adipose tissue; nerve; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q22
UniSTS entry: ADAM10
UniSTS entry: Chr 15 RH17532 [Map Viewer]
UniSTS entry: Chr 15 D15S686E
UniSTS entry: Chr 15 RH45136 [Map Viewer]
UniSTS entry: Adam10
UniSTS entry: Chr 15 RH45709 [Map Viewer]
UniSTS entry: Chr 15 ADAM10_1576
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BC055087.1 Homo sapiens ADAM metallopeptidase domain 10, mRNA (cDNA clone IMAGE:4698521) A
NM_001110.2 Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), mRNA P
AK023460.1 Homo sapiens cDNA FLJ13398 fis, clone PLACE1001377, highly similar to Homo sapiens ADAM10 (ADAM10) mRNA P
BC104659.1 Homo sapiens ADAM metallopeptidase domain 10, mRNA (cDNA clone IMAGE:4657963) A
BC126253.1 Homo sapiens ADAM metallopeptidase domain 10, mRNA (cDNA clone MGC:161531 IMAGE:8991969), complete cds P
Z48579.1 H.sapiens mRNA for disintegrin-metalloprotease (partial) P
AK300472.1 Homo sapiens cDNA FLJ57594 complete cds, highly similar to ADAM 10 precursor (EC 3.4.24.81) (Adisintegrin and metalloproteinase domain 10) P
BC143935.1 Homo sapiens cDNA clone IMAGE:9052453 P
AF009615.1 Homo sapiens ADAM10 (ADAM10) mRNA, complete cds P

EST sequences (10 of 422) [Show all sequences]

AI161066.1 Clone IMAGE:1715666 placenta 3' read
BX107550.1 Clone IMAGp998A18571_;_IMAGE:261401 skin
CB146020.1 Clone L16HLK3-13-C10 liver 5' read P
CB128450.1 Clone L11SNU354-22-F06 liver 5' read
CB177347.1 Clone IMAGE:6365334 pancreas 5' read
AI273896.1 Clone IMAGE:1964283 ovary 3' read A
AI669576.1 Clone IMAGE:2261546 uterus 3' read PA
AI680390.1 Clone IMAGE:2264325 uterus 3' read
CB243711.1 Clone UI-CF-FN0-agf-b-16-0-UI lung 3' read A
AL037253.1 Clone DKFZp564A2270 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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