Acetyl-CoA acetyltransferase 2 (ACAT2)

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UGID:1844024 UniGene Hs.571037 Homo sapiens (human) ACAT2

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Acetyl-CoA acetyltransferase 2 (ACAT2)

Human protein-coding gene ACAT2. Represented by 609 ESTs from 227 cDNA libraries. Corresponds to reference sequence NM_005891.2. [UniGene 1844024 - Hs.571037]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_005882.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ACAT2 gene product	H. sapiens	100.0	396
XP_001143759.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: acetyl-CoA acetyltransferase, cytosolic	P. troglodytes	99.8	396
NP_033364.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Acat2 gene product	M. musculus	90.4	396
NP_001079879.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	acetyl-CoA acetyltransferase 2	X. laevis	78.8	396
NP_571445.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	acat2 gene product	D. rerio	74.6	393
NP_612094.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CG9149	D. melanogaster	61.0	391
XP_964434.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	acetyl-CoA acetyltransferase	N. crassa	51.2	389
XP_001697225.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	acetyl-CoA acyltransferase	C. reinhardtii	51.0	241
NP_499752.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein F53A2.7	C. elegans	50.8	250
NP_851154.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	acetyl-CoA acetyltransferase, cytosolic 1	A. thaliana	49.5	396
Other hits (2 of 64) [Show all]		Species	Id(%)	Len(aa)
XP_003898406.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: acetyl-CoA acetyltransferase, cytosolic isoform 2	P. anubis	96.9	425
XP_001106967.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: acetyl-CoA acetyltransferase, cytosolic isoform 2	M. mulatta	92.7	396

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; uncharacterized tissue; lung; embryonic tissue; prostate; skin; mixed; lymph; blood; nerve; thyroid; liver; mammary gland; uterus; parathyroid; kidney; testis; bone marrow; bladder; eye; intestine; placenta; ovary; pancreas; tonsil; pharynx; muscle; spinal cord; salivary gland; spleen; adrenal gland; bone; heart; mouth; ascites; lymph node; cervix; pituitary gland; stomach; connective tissue; vascular; esophagus; larynx

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	6
Map position:	6q25.3
UniSTS entry:	Chr 6	G43314
UniSTS entry:	Chr 6	D6S1840	[Map Viewer]
UniSTS entry:	Chr 12	SHGC-36020

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_005891.2	Homo sapiens acetyl-CoA acetyltransferase 2 (ACAT2), mRNA	PA
AB208993.1	Homo sapiens mRNA for Acetyl-CoA acetyltransferase, cytosolic variant protein	P
BC000408.2	Homo sapiens acetyl-Coenzyme A acetyltransferase 2, mRNA (cDNA clone MGC:8573 IMAGE:2823036), complete cds	PA
AK225244.1	Homo sapiens mRNA for Acetyl-CoA acetyltransferase, cytosolic variant, clone: DMC03734	P
AK225089.1	Homo sapiens mRNA for Acetyl-CoA acetyltransferase, cytosolic variant, clone: CAS06280	PA
AK291080.1	Homo sapiens cDNA FLJ76813 complete cds, highly similar to Homo sapiens acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase), mRNA	PA
AF356877.1	Homo sapiens acetyl CoA transferase-like protein mRNA, complete cds	P
AK294273.1	Homo sapiens cDNA FLJ53975 complete cds, highly similar to Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9)	P
S70154.1	cytosolic acetoacetyl-coenzyme A thiolase [human, liver, mRNA, 1490 nt]	PA

EST sequences (10 of 609) [Show all sequences]

R15962.1	Clone IMAGE:53139	brain	5' read	P
AA988862.1	Clone IMAGE:1602079	lung	3' read	A
AI033701.1	Clone IMAGE:1647984	parathyroid	3' read	PA
AI038073.1	Clone IMAGE:1656970	mixed	3' read	P
AI040115.1	Clone IMAGE:1655749	mixed	3' read	A
AI051602.1	Clone IMAGE:1674141	mixed	3' read	PA
BX094208.1	Clone IMAGp998C06652_;_IMAGE:292541	mixed		P
AI184756.1	Clone IMAGE:1723477	placenta	3' read	A
R25823.1	Clone IMAGE:36393	brain	5' read
AI193574.1	Clone IMAGE:1744380	lung	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria