> Inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1)
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UGID:1782784     UniGene Hs.567295     Homo sapiens (human)   ITPR1
Inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1)

Human protein-coding gene ITPR1. Represented by 224 ESTs from 129 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 1782784 - Hs.567295]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001161744.1 ITPR1 gene product H. sapiens 100.0 2742
XP_003309639.2 PREDICTED: inositol 1,4,5-trisphosphate receptor type 1 isoform 3 P. troglodytes 99.9 2742
XP_003894206.1 PREDICTED: inositol 1,4,5-trisphosphate receptor type 1 P. anubis 99.6 2757
NP_034715.3 Itpr1 gene product M. musculus 99.3 2748
NP_001084015.1 inositol 1,4,5-trisphosphate receptor, type 1 X. laevis 92.8 2692
XP_001921194.2 PREDICTED: inositol 1,4,5-trisphosphate receptor type 1 D. rerio 90.7 2748
NP_730942.1 inositol 1,4,5,-tris-phosphate receptor, isoform A D. melanogaster 67.2 2812
NP_001023173.1 Protein ITR-1, isoform f C. elegans 54.6 2842
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_001496579.3 PREDICTED: inositol 1,4,5-trisphosphate receptor type 1 isoform 2 E. caballus 99.3 2659
NP_001257525.1 inositol 1,4,5-trisphosphate receptor type 1 isoform 2 R. norvegicus 99.3 2732

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; uterus; parathyroid; nerve; ear; thyroid; adrenal gland; lung; kidney; trachea; connective tissue; lymph node; muscle; vascular; prostate; intestine; testis; eye; embryonic tissue; pituitary gland; mouth; thymus; liver; mixed; placenta; skin; bone; bladder; ovary; pancreas; bone marrow; ganglia; cervix; blood
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p26.1
UniSTS entry: Chr 3 G19634
UniSTS entry: Chr 3 A001T36 [Map Viewer]
UniSTS entry: Chr 3 IB262 [Map Viewer]
UniSTS entry: Chr 3 D3S3340 [Map Viewer]
UniSTS entry: Chr 3 ITPR1
UniSTS entry: Chr 1 ha3079
UniSTS entry: Chr 3 RH68059
UniSTS entry: Chr 3 SHGC-59934
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

BX647588.1 Homo sapiens mRNA; cDNA DKFZp313F1630 (from clone DKFZp313F1630) PA
BX640953.1 Homo sapiens mRNA; cDNA DKFZp686E21132 (from clone DKFZp686E21132) PA
D26070.1 Homo sapiens mRNA for type 1 inositol 1,4,5-trisphosphate receptor, complete cds P
AB208868.1 Homo sapiens mRNA for Inositol 1,4,5-trisphosphate receptor type 1 variant protein P
NM_002222.5 Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 2, mRNA P
NM_001099952.2 Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 1, mRNA P
L38019.2 Homo sapiens inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) mRNA, complete cds P
AK311008.1 Homo sapiens cDNA, FLJ18050 P
AK309981.1 Homo sapiens cDNA, FLJ17023 P
AK294594.1 Homo sapiens cDNA FLJ54348 complete cds, highly similar to Inositol 1,4,5-trisphosphate receptor type 1 P
AK293752.1 Homo sapiens cDNA FLJ51757 partial cds, highly similar to Inositol 1,4,5-trisphosphate receptor type 1 P
AK296235.1 Homo sapiens cDNA FLJ50742 complete cds, highly similar to Inositol 1,4,5-trisphosphate receptor type 1 P
S82269.1 inositol 1,4,5 trisphosphate receptor [human, Epstein Barr Virus-transformed lymphoblastoid cells, mRNA Partial, 527 nt] P
BC144563.1 Homo sapiens inositol 1,4,5-triphosphate receptor, type 1, mRNA (cDNA clone IMAGE:9053091), complete cds PA
NM_001168272.1 Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 3, mRNA P
U23850.1 Human inositol 1,4,5 trisphosphate receptor type 1 mRNA, partial cds P

EST sequences (10 of 224) [Show all sequences]

R18369.1 Clone IMAGE:30928 brain 5' read
AI026081.1 Clone IMAGE:1647297 parathyroid 3' read A
AI031829.1 Clone IMAGE:1645986 parathyroid 3' read A
AA947486.1 Clone IMAGE:1589820 kidney 3' read A
AI079803.1 Clone IMAGE:1668613 parathyroid 3' read A
CB068376.1 Clone IMAGE:6365315 pancreas 3' read
BX091317.1 Clone IMAGp998H134030_;_IMAGE:1589820 kidney P
AI189151.1 Clone IMAGE:1722703 placenta 3' read
AI206453.1 Clone IMAGE:1758588 placenta 3' read A
AI222657.1 Clone IMAGE:1762064 kidney 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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