> Aconitase 1, soluble (ACO1)
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UGID:1782718     UniGene Hs.567229     Homo sapiens (human)   ACO1
Aconitase 1, soluble (ACO1)

Human protein-coding gene ACO1. Represented by 448 ESTs from 219 cDNA libraries. Corresponds to reference sequence NM_002197.2. [UniGene 1782718 - Hs.567229]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001156102.1 PREDICTED: cytoplasmic aconitate hydratase isoform 4 P. troglodytes 100.0 888
NP_002188.1 ACO1 gene product H. sapiens 100.0 888
XP_001103761.1 PREDICTED: cytoplasmic aconitate hydratase isoform 2 M. mulatta 99.8 888
XP_003911667.1 PREDICTED: cytoplasmic aconitate hydratase P. anubis 99.8 888
NP_031412.2 Aco1 gene product M. musculus 95.8 888
NP_001080577.1 aconitase 1, soluble X. laevis 89.3 889
NP_001030155.1 aco1 gene product D. rerio 88.1 889
NP_524303.2 iron regulatory protein 1B D. melanogaster 76.6 894
NP_509898.1 Protein ACO-1 C. elegans 73.2 868
NP_195308.1 aconitate hydratase 1 A. thaliana 68.5 893
Other hits (2 of 50) [Show all]SpeciesId(%)Len(aa)
XP_001497856.2 PREDICTED: cytoplasmic aconitate hydratase E. caballus 97.2 852
XP_003357777.1 PREDICTED: cytoplasmic aconitate hydratase S. scrofa 96.8 888

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; lung; mixed; uterus; kidney; placenta; trachea; cervix; adipose tissue; intestine; connective tissue; mammary gland; eye; liver; uncharacterized tissue; embryonic tissue; skin; thyroid; adrenal gland; thymus; prostate; blood; stomach; vascular; heart; muscle; pancreas; ascites; mouth; bone; amniotic fluid; lymph; ovary; spleen; nerve; ganglia; pineal gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9p21.1
UniSTS entry: Chr 9 RH70753
UniSTS entry: Chr 9 D9S1955 [Map Viewer]
UniSTS entry: Chr 9 WI-21068 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

BX538349.1 Homo sapiens mRNA; cDNA DKFZp686P10119 (from clone DKFZp686P10119) PA
NM_002197.2 Homo sapiens aconitase 1, soluble (ACO1), mRNA PA
AB209480.1 Homo sapiens mRNA for aconitase 1 variant protein P
AF261088.1 Homo sapiens iron regulatory protein 1 (IRP1) mRNA, complete cds PA
AK057904.1 Homo sapiens cDNA FLJ25175 fis, clone CBR08906, highly similar to IRON-RESPONSIVE ELEMENT BINDING PROTEIN 1 P
BC018103.1 Homo sapiens aconitase 1, soluble, mRNA (cDNA clone MGC:8709 IMAGE:3915517), complete cds PA
AK308752.1 Homo sapiens cDNA, FLJ98793 P
Z11559.1 H.sapiens mRNA for iron regulatory factor P
M58510.1 Human iron-responsive element-binding protein/iron regulatory protein 1 (IRE-BP1/IRP1) mRNA, partial cds P

EST sequences (10 of 448) [Show all sequences]

AI127153.1 Clone IMAGE:1708196 heart 3' read
BX102388.1 Clone IMAGp998F06128_;_IMAGE:126725 mixed P
AI168066.1 Clone IMAGE:1682483 skin 3' read A
AI168068.1 Clone IMAGE:1682487 skin 3' read A
CB163622.1 Clone L17N670205n1-25-F03 liver 5' read P
CB164755.1 Clone L17N670205n1-13-B11 liver 5' read P
CB115318.1 Clone L3SNU475s1-10-E03 liver 5' read P
CB114185.1 Clone L3SNU475s1-8-F02 liver 5' read P
CB131305.1 Clone L13SNU387-5-C04 liver 5' read P
CB148539.1 Clone L15CKK1-42-A07 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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