> Heparan sulfate proteoglycan 2 (HSPG2)
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UGID:1777771     UniGene Hs.562227     Homo sapiens (human)   HSPG2 Links
Heparan sulfate proteoglycan 2 (HSPG2)

Human protein-coding gene HSPG2. Represented by 590 ESTs from 236 cDNA libraries. Corresponds to reference sequence NM_005529.5. [UniGene 1777771 - Hs.562227]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005520.4 HSPG2 gene product H. sapiens 100.0 4390
NP_032331.2 Hspg2 gene product M. musculus 88.5 4382
XP_003201256.1 PREDICTED: basement membrane-specific heparan sulfate proteoglycan core protein D. rerio 58.0 3629
NP_497047.1 Protein UNC-52, isoform b C. elegans 54.0 198
NP_001027036.2 terribly reduced optic lobes, isoform J D. melanogaster 51.7 205
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_001099299.2 PREDICTED: basement membrane-specific heparan sulfate proteoglycan core protein M. mulatta 98.4 4415
XP_003891336.1 PREDICTED: basement membrane-specific heparan sulfate proteoglycan core protein P. anubis 98.3 4391

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: embryonic tissue; uterus; uncharacterized tissue; pancreas; placenta; brain; skin; intestine; lung; mixed; spleen; muscle; eye; trachea; stomach; prostate; kidney; adrenal gland; nerve; mammary gland; testis; liver; connective tissue; heart; bone; ascites; thyroid; bladder; larynx; thymus; adipose tissue; blood; epididymis; ganglia; ovary; mouth; amniotic fluid; vascular; esophagus; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p36.1-p34
UniSTS entry: Chr 1 RH79675
UniSTS entry: Chr 1 G15904
UniSTS entry: Chr 1 GDB:549190
UniSTS entry: Chr 1 STS-M85289 [Map Viewer]
UniSTS entry: Chr 3 SHGC-74354 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_005529.5 Homo sapiens heparan sulfate proteoglycan 2 (HSPG2), mRNA PA
M85289.1 Human heparan sulfate proteoglycan (HSPG2) mRNA, complete cds P
AB209851.1 Homo sapiens mRNA for Basement membrane-specific heparan sulfate proteoglycan core protein precursor variant protein P
BC109204.1 Homo sapiens heparan sulfate proteoglycan 2, mRNA (cDNA clone IMAGE:40005996), partial cds P
AF479675.1 Homo sapiens perlecan variant miniperl mRNA, complete cds; alternatively spliced P
X62515.1 H.sapiens mRNA for basement membrane heparan sulfate proteoglycan P
BC033152.1 Homo sapiens heparan sulfate proteoglycan 2, mRNA (cDNA clone IMAGE:4131756), with apparent retained intron PA
S76436.1 Homo sapiens heparan sulfate proteoglycan core protein (HSPG2) mRNA, partial cds P
M64283.1 Human heparan sulfate proteoglycan (HSPG2) protein core mRNA, partial cds P

EST sequences (10 of 590) [Show all sequences]

AA905568.1 Clone IMAGE:1506262 mixed 3' read A
AA974966.1 Clone IMAGE:1555509 kidney 3' read A
AA977215.1 Clone IMAGE:1587411 uncharacterized tissue 3' read A
AI125812.1 Clone IMAGE:1737296 testis 3' read A
AI131329.1 Clone IMAGE:1709947 heart 3' read A
AI139149.1 Clone IMAGE:1710051 heart 3' read A
R23999.1 Clone IMAGE:131137 placenta 5' read P
BX104519.1 Clone IMAGp998G16245_;_IMAGE:155559 mammary gland
AI188115.1 Clone IMAGE:1734372 testis 3' read P
R26043.1 Clone IMAGE:132739 placenta 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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