> Dynamin 1-like (DNM1L)
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UGID:1633101     UniGene Hs.556296     Homo sapiens (human)   DNM1L Order cDNA clone, Links
Dynamin 1-like (DNM1L)

Human protein-coding gene DNM1L. Represented by 1072 ESTs from 283 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 1633101 - Hs.556296]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001086230.2 PREDICTED: dynamin 1-like isoform 5 M. mulatta 100.0 788
XP_003906239.1 PREDICTED: dynamin-1-like protein isoform 4 P. anubis 100.0 762
NP_036192.2 DNM1L gene product H. sapiens 100.0 735
XP_003481715.1 PREDICTED: dynamin 1-like S. scrofa 100.0 666
NP_001039959.1 DNM1L gene product B. taurus 99.9 748
XP_864886.1 PREDICTED: dynamin 1-like isoform 3 C. lupus familiaris 99.9 735
XP_004007581.1 PREDICTED: dynamin-1-like protein O. aries 99.9 723
NP_446107.2 Dnm1l gene product R. norvegicus 99.9 715
XP_002712725.1 PREDICTED: dynamin 1-like O. cuniculus 99.9 711
NP_690029.2 Dnm1l gene product M. musculus 99.7 711
NP_001080183.1 dynamin 1-like X. laevis 95.7 697
NP_957216.1 dnm1l gene product D. rerio 94.7 690
NP_608694.2 dynamin related protein 1, isoform A D. melanogaster 75.8 734
NP_741403.2 Protein DRP-1, isoform b C. elegans 70.2 711
XP_964068.1 hypothetical protein NCU09808 N. crassa 58.6 575
NP_565362.1 dynamin-related protein 3B A. thaliana 57.9 525
XP_001697229.1 dynamin-related GTPase C. reinhardtii 55.7 517
NP_013100.1 Dnm1p S. cerevisiae 54.3 753
Other hits (2 of 57) [Show all]SpeciesId(%)Len(aa)
XP_003341941.1 PREDICTED: dynamin 1-like M. domestica 99.2 735
XP_003365209.1 PREDICTED: dynamin-1-like protein-like E. caballus 98.9 791

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; connective tissue; uterus; placenta; mouth; embryonic tissue; lung; uncharacterized tissue; kidney; liver; skin; vascular; thymus; eye; trachea; mixed; spleen; prostate; intestine; blood; stomach; ear; parathyroid; ascites; lymph node; thyroid; bone marrow; mammary gland; esophagus; cervix; heart; pituitary gland; ovary; bladder; lymph; pineal gland; bone; pancreas; muscle; nerve; salivary gland; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p11.21
UniSTS entry: Chr 12 RH15679
UniSTS entry: Chr 12 SGC30841 [Map Viewer]
UniSTS entry: Chr 12 G59502
UniSTS entry: Chr 12 G43506
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 1 RH80030
UniSTS entry: Chr 12 DNM1L_7961
UniSTS entry: MARC_31555-31556:1045589022:1
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AF061795.1 Homo sapiens dynamin-like protein Dymple isoform mRNA, complete cds PA
NM_005690.3 Homo sapiens dynamin 1-like (DNM1L), transcript variant 3, mRNA P
NM_012062.3 Homo sapiens dynamin 1-like (DNM1L), transcript variant 1, mRNA P
NM_012063.2 Homo sapiens dynamin 1-like (DNM1L), transcript variant 2, mRNA P
AF151685.1 Homo sapiens dynamin-like protein DYNIV-11 (DYNIV-11) mRNA, alternatively spliced, complete cds PA
AB209070.1 Homo sapiens mRNA for Dynamin-like protein DYNIV-11 variant protein P
BC107763.1 Homo sapiens dynamin 1-like, mRNA (cDNA clone IMAGE:4608153), partial cds PA
AK291094.1 Homo sapiens cDNA FLJ76814 complete cds, highly similar to Homo sapiens dynamin 1-like (DNM1L), transcript variant 3, mRNA PA
AK311606.1 Homo sapiens cDNA, FLJ18648 P
BC024590.1 Homo sapiens dynamin 1-like, mRNA (cDNA clone MGC:9157 IMAGE:3882922), complete cds PA
AK090788.1 Homo sapiens cDNA FLJ33469 fis, clone BRAMY2002005
AK294533.1 Homo sapiens cDNA FLJ59504 complete cds, highly similar to Dynamin-1-like protein (EC 3.6.5.5) P
AK293290.1 Homo sapiens cDNA FLJ59840 complete cds, highly similar to Dynamin-1-like protein (EC 3.6.5.5) P
AK298568.1 Homo sapiens cDNA FLJ59948 complete cds, highly similar to Dynamin-1-like protein (EC 3.6.5.5) P
AK299926.1 Homo sapiens cDNA FLJ55044 complete cds, highly similar to Dynamin-1-like protein (EC 3.6.5.5) P
AK302565.1 Homo sapiens cDNA FLJ56381 complete cds, highly similar to Dynamin-1-like protein (EC 3.6.5.5) P
AF000430.1 Homo sapiens dynamin-like protein mRNA, complete cds PA
AB006965.1 Homo sapiens mRNA for Dnm1p/Vps1p-like protein, complete cds P

EST sequences (10 of 1072) [Show all sequences]

AA974831.1 Clone IMAGE:1567640 lung 3' read A
AA977240.1 Clone IMAGE:1558795 lung 3' read A
AI004869.1 Clone IMAGE:1621043 testis 3' read A
AI018043.1 Clone IMAGE:1642094 testis 3' read A
AI093392.1 Clone IMAGE:1695195 uterus 3' read PA
AA862848.1 Clone IMAGE:1469763 uncharacterized tissue 3' read A
AI138553.1 Clone IMAGE:1735835 testis 3' read
R23670.1 Clone IMAGE:33981 brain 5' read P
CB045649.1 Clone IMAGE:3218466 intestine 5' read P
CB046208.1 Clone IMAGE:3252404 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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