> Apoptotic peptidase activating factor 1 (APAF1)
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UGID:1506046     UniGene Hs.552567     Homo sapiens (human)   APAF1 Order cDNA clone, Links
Apoptotic peptidase activating factor 1 (APAF1)

Human protein-coding gene APAF1. Represented by 85 ESTs from 60 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 1506046 - Hs.552567]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_863651.1 APAF1 gene product H. sapiens 100.0 1247
XP_003313928.1 PREDICTED: apoptotic protease-activating factor 1 P. troglodytes 99.8 1247
NP_001036023.1 Apaf1 gene product M. musculus 89.8 1248
NP_001085834.1 apoptotic peptidase activating factor 1 X. laevis 65.0 1247
NP_571683.1 apaf1 gene product D. rerio 57.3 1257
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_001087067.1 PREDICTED: apoptotic protease-activating factor 1 isoform 4 M. mulatta 98.6 1247
XP_003907055.1 PREDICTED: LOW QUALITY PROTEIN: apoptotic protease-activating factor 1 P. anubis 97.8 1205

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; uncharacterized tissue; muscle; mammary gland; skin; embryonic tissue; testis; eye; placenta; blood; bone marrow; trachea; thymus; kidney; ear; intestine; parathyroid; liver; ascites; lymph node; uterus; heart; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q23
UniSTS entry: Chr 1 GDB:434012
UniSTS entry: Chr 12 RH69665
UniSTS entry: Chr 1 L17791
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 GDB:313557
UniSTS entry: Chr 1 PMC156606P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (26)

AB103079.1 Homo sapiens APAF-1-ALT mRNA for apoptotic protease activating factor 1, complete cds P
NM_181869.1 Homo sapiens apoptotic peptidase activating factor 1 (APAF1), transcript variant 5, mRNA PA
NM_181868.1 Homo sapiens apoptotic peptidase activating factor 1 (APAF1), transcript variant 4, mRNA PA
NM_181861.1 Homo sapiens apoptotic peptidase activating factor 1 (APAF1), transcript variant 3, mRNA PA
AJ243003.1 Homo sapiens mRNA for apoptotic protease activating factor 1, cell line Colo 320 P
AJ243004.1 Homo sapiens mRNA for apoptotic protease activating factor 1, cell line HDLM-2 P
AJ243005.1 Homo sapiens mRNA for apoptotic protease activating factor 1, cell line Hela P
AJ243006.1 Homo sapiens mRNA for apoptotic protease activating factor 1, cell line Karpas 299 P
AJ243007.1 Homo sapiens mRNA for apoptotic protease activating factor 1, cell line KM-H2 P
AJ243008.1 Homo sapiens mRNA for apoptotic protease activating factor 1, cell line L 1236 P
AJ243009.1 Homo sapiens mRNA for apoptotic protease activating factor 1, cell line L 428 P
AJ243010.1 Homo sapiens mRNA for apoptotic protease activating factor 1, cell line Tera II P
AJ243011.1 Homo sapiens mRNA for protease activating factor-1 P
AJ243048.1 Homo sapiens mRNA for apoptotic protease activating factor 1 (Apaf-1 gene) P
NM_001160.2 Homo sapiens apoptotic peptidase activating factor 1 (APAF1), transcript variant 2, mRNA PA
NM_013229.2 Homo sapiens apoptotic peptidase activating factor 1 (APAF1), transcript variant 1, mRNA PA
AF149794.1 Homo sapiens apoptotic protease activating factor 1 (APAF1) mRNA, complete cds P
AF134397.1 Homo sapiens apoptotic protease activating factor-1 long isoform APAF-1L (APAF-1) mRNA, complete cds P
AF248734.1 Homo sapiens apoptotic protease activating factor 1 variant, mRNA, complete cds P
EF560718.1 Homo sapiens clone DKFZp781B1145 APAF1 protein (APAF1) mRNA, complete cds P
BC150255.1 Homo sapiens apoptotic peptidase activating factor 1, mRNA (cDNA clone MGC:166813 IMAGE:9007183), complete cds PA
AK307509.1 Homo sapiens cDNA, FLJ97457 P
BC136531.1 Homo sapiens apoptotic peptidase activating factor 1, mRNA (cDNA clone MGC:168144 IMAGE:9020521), complete cds P
BC136532.1 Homo sapiens apoptotic peptidase activating factor 1, mRNA (cDNA clone MGC:168145 IMAGE:9020522), complete cds P
AF013263.1 Homo sapiens apoptotic protease activating factor 1 (Apaf-1) mRNA, complete cds PA
AB007873.2 Homo sapiens KIAA0413 mRNA, partial cds P

EST sequences (10 of 85) [Show all sequences]

R15148.1 Clone IMAGE:29538 brain 5' read
AI242553.1 Clone IMAGE:1856731 mixed 3' read A
AI371445.1 Clone IMAGE:2011198 brain 3' read A
AI375163.1 Clone IMAGE:2063405 mixed 3' read A
R47331.1 Clone e859-r heart
AI378749.1 Clone IMAGE:2064227 mixed 3' read
T08308.1 Clone HIBBC25 brain 5' read
R41570.1 Clone IMAGE:29538 brain 3' read A
AI743892.1 Clone IMAGE:2368889 mixed 3' read P
BX280771.1 Clone IMAGp998P1812350_;_IMAGE:5585153 uncharacterized tissue P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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