> Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) (SRD5A1)
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UGID:130781     UniGene Hs.552     Homo sapiens (human)   SRD5A1 Order cDNA clone, Links
Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) (SRD5A1)

Human protein-coding gene SRD5A1. Represented by 272 ESTs from 131 cDNA libraries. Corresponds to reference sequence NM_001047.2. [UniGene 130781 - Hs.552]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001144570.1 PREDICTED: 3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform 2 P. troglodytes 100.0 258
NP_001038.1 SRD5A1 gene product H. sapiens 100.0 258
NP_780492.2 Srd5a1 gene product M. musculus 74.8 250
NP_001070121.1 srd5a1 gene product D. rerio 64.4 247
NP_001092166.1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) X. laevis 62.1 247
NP_510071.1 Protein F42F12.3 C. elegans 50.0 175
XP_001696975.1 hypothetical protein CHLREDRAFT_120014 C. reinhardtii 47.7 173
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_001083405.1 PREDICTED: 3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform 2 M. mulatta 96.6 262
XP_003899533.1 PREDICTED: 3-oxo-5-alpha-steroid 4-dehydrogenase 1 P. anubis 96.2 262

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pancreas; adrenal gland; muscle; mouth; testis; blood; embryonic tissue; connective tissue; prostate; liver; mixed; intestine; uncharacterized tissue; uterus; eye; skin; stomach; mammary gland; esophagus; spleen; thymus; trachea; ear; lymph; cervix; bone marrow; lymph node; bone; kidney; placenta; vascular; ascites; ovary; lung; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5p15
UniSTS entry: Chr 5 RH78527 [Map Viewer]
UniSTS entry: Chr 5 SGC30358 [Map Viewer]
UniSTS entry: Chr 5 WI-18821 [Map Viewer]
UniSTS entry: Chr 5 D5S2373 [Map Viewer]
UniSTS entry: Chr 5 RH41119
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AF052126.1 Homo sapiens clone 23823 steroid 5-alpha-reductase mRNA, complete cds PA
BT006834.1 Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) mRNA, complete cds P
NM_001047.2 Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) (SRD5A1), mRNA PA
AF113128.1 Homo sapiens steroid-5-alpha-reductase isoform mRNA, complete cds PA
BC007033.1 Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), mRNA (cDNA clone MGC:12396 IMAGE:3683274), complete cds PA
BC008673.2 Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), mRNA (cDNA clone MGC:9503 IMAGE:3868483), complete cds PA
AK313070.1 Homo sapiens cDNA, FLJ93551, Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1(3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) (SRD5A1),mRNA P
BC006373.2 Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), mRNA (cDNA clone IMAGE:4138835) PA
AK315996.1 Homo sapiens cDNA, FLJ78895 complete cds, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5) P
AK297511.1 Homo sapiens cDNA FLJ52969 complete cds, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.99.5) P
AK297208.1 Homo sapiens cDNA FLJ60681 complete cds P
M32313.1 Human steroid 5-alpha-reductase mRNA, complete cds P

EST sequences (10 of 272) [Show all sequences]

AI140805.1 Clone IMAGE:1566229 mixed 3' read A
AI222948.1 Clone IMAGE:1883342 lung 3' read A
AI224018.1 Clone IMAGE:2000160 lymph node 3' read A
AI281161.1 Clone IMAGE:1873170 intestine 3' read A
AI285240.1 Clone IMAGE:1873317 intestine 3' read A
AI304563.1 Clone IMAGE:1912429 intestine 3' read A
R36874.1 Clone IMAGE:25679 brain 3' read A
AI363117.1 Clone IMAGE:2017137 brain 3' read
AI375514.1 Clone IMAGE:2065428 embryonic tissue 3' read A
CB218113.1 Clone IMAGE:5795549 bone 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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