> Surfactant protein A1 (SFTPA1)
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UGID:1371609     UniGene Hs.535295     Homo sapiens (human)   SFTPA1 Order cDNA clone, Links
Surfactant protein A1 (SFTPA1)

Human protein-coding gene SFTPA1. Represented by 320 ESTs from 45 cDNA libraries. EST representation biased toward adult. Corresponds to 6 reference sequences (different isoforms). [UniGene 1371609 - Hs.535295]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001087239.2 SFTPA1 gene product H. sapiens 100.0 262
XP_001152394.2 PREDICTED: pulmonary surfactant-associated protein A1 isoform 2 P. troglodytes 99.6 262
NP_075623.2 Sftpa1 gene product M. musculus 74.2 247
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_002805703.1 PREDICTED: pulmonary surfactant-associated protein A2 isoform 2 M. mulatta 93.5 262
XP_003903762.1 PREDICTED: pulmonary surfactant-associated protein A1-like isoform 3 P. anubis 93.2 264

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; connective tissue; mixed; blood; prostate; kidney; uncharacterized tissue; lymph node; pancreas
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q22.3
UniSTS entry: Chr 10 STS-T63485
UniSTS entry: Chr 10 GDB:193873
UniSTS entry: Chr 10 GDB:278158
UniSTS entry: Chr 10 SFTPA1
UniSTS entry: Chr 6 STS-M57466 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (33)

NM_005411.4 Homo sapiens surfactant protein A1 (SFTPA1), transcript variant 1, mRNA PA
M13686.1 Human pulmonary surfactant-associated protein mRNA, complete cds, clone MPSAP-6A P
BC111570.1 Homo sapiens surfactant protein A1B, mRNA (cDNA clone MGC:133365 IMAGE:40069324), complete cds P
NM_001093770.2 Homo sapiens surfactant protein A1 (SFTPA1), transcript variant 2, mRNA PA
AK290703.1 Homo sapiens cDNA FLJ77898 complete cds, highly similar to Homo sapiens surfactant, pulmonary-associated protein A1 (SFTPA1), mRNA P
AK309518.1 Homo sapiens cDNA, FLJ99559 P
AK298092.1 Homo sapiens cDNA FLJ61144 complete cds, highly similar to Pulmonary surfactant-associated protein A1 precursor P
AK298034.1 Homo sapiens cDNA FLJ50593 complete cds, moderately similar to Pulmonary surfactant-associated protein A1 precursor P
AK298029.1 Homo sapiens cDNA FLJ51913 complete cds, highly similar to Pulmonary surfactant-associated protein A1 precursor P
AK298002.1 Homo sapiens cDNA FLJ54288 complete cds, moderately similar to Pulmonary surfactant-associated protein A1 precursor P
BC029913.2 Homo sapiens surfactant protein A1B, mRNA (cDNA clone IMAGE:5175402), partial cds P
S69690.1 SP-A1=SP-A1 epsilon {5' region, alternatively spliced} [human, fetal lung explants, mRNA Partial, 203 nt]
S69686.1 SP-A1=SP-A1 beta {5' region, alternatively spliced} [human, fetal lung explants, mRNA Partial, 137 nt]
S69685.1 SP-A1=SP-A1 alpha {5' region, alternatively spliced} [human, fetal lung explants, mRNA Partial, 132 nt]
S69681.1 SP-A2=SP-2A beta {5' region, alternatively spliced} [human, fetal lung explants, mRNA Partial, 170 nt]
BC171875.1 Homo sapiens surfactant protein A1B, mRNA (cDNA clone MGC:198590 IMAGE:9054529), complete cds P
AK316196.1 Homo sapiens cDNA, FLJ79095 complete cds, highly similar to Pulmonary surfactant-associated protein A2 precursor P
NM_001164647.1 Homo sapiens surfactant protein A1 (SFTPA1), transcript variant 4, mRNA PA
NM_001164646.1 Homo sapiens surfactant protein A1 (SFTPA1), transcript variant 6, mRNA PA
NM_001164645.1 Homo sapiens surfactant protein A1 (SFTPA1), transcript variant 5, mRNA PA
NM_001164644.1 Homo sapiens surfactant protein A1 (SFTPA1), transcript variant 3, mRNA PA
HQ021442.1 Homo sapiens surfactant protein A1 variant ACD' 6A4 (SFTPA1) mRNA, complete cds, alternatively spliced P
HQ021441.1 Homo sapiens surfactant protein A1 variant ACD' 6A3 (SFTPA1) mRNA, complete cds, alternatively spliced P
HQ021440.1 Homo sapiens surfactant protein A1 variant ACD' 6A2 (SFTPA1) mRNA, complete cds, alternatively spliced P
HQ021439.1 Homo sapiens surfactant protein A1 variant AB'D' 6A4 (SFTPA1) mRNA, complete cds, alternatively spliced P
HQ021438.1 Homo sapiens surfactant protein A1 variant AB'D' 6A3 (SFTPA1) mRNA, complete cds, alternatively spliced P
HQ021437.1 Homo sapiens surfactant protein A1 variant AB'D' 6A2 (SFTPA1) mRNA, complete cds, alternatively spliced P
HQ021436.1 Homo sapiens surfactant protein A1 variant AD' 6A4 (SFTPA1) mRNA, complete cds, alternatively spliced P
HQ021435.1 Homo sapiens surfactant protein A1 variant AD' 6A3 (SFTPA1) mRNA, complete cds, alternatively spliced P
HQ021434.1 Homo sapiens surfactant protein A1 variant AD' 6A2 (SFTPA1) mRNA, complete cds, alternatively spliced P
HQ021433.2 Homo sapiens surfactant protein A1 variant AD' 6A (SFTPA1) mRNA, complete cds, alternatively spliced P
JX502765.1 Homo sapiens surfactant protein A1 variant ACD' 6A (SFTPA1) mRNA, complete cds, alternatively spliced P
JX502764.1 Homo sapiens surfactant protein A1 variant AB'D' 6A (SFTPA1) mRNA, complete cds, alternatively spliced P

EST sequences (10 of 320) [Show all sequences]

AA910449.1 Clone IMAGE:1505529 mixed 3' read P
AA969323.1 Clone IMAGE:1580494 mixed 3' read
AA969402.1 Clone IMAGE:1580542 mixed 3' read
AA988528.1 Clone IMAGE:1602509 lung 3' read
AA994009.1 Clone IMAGE:1628938 mixed 3' read
AA926698.1 Clone IMAGE:1542020 mixed 3' read
AA928513.1 Clone IMAGE:1541350 mixed 3' read
BX103079.1 Clone IMAGp998O054432_;_IMAGE:1744348 lung
AI299538.1 Clone IMAGE:1897947 lung 3' read A
AI797761.1 Clone IMAGE:2347650 mixed 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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