> Ceroid-lipofuscinosis, neuronal 3 (CLN3)
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UGID:1370981     UniGene Hs.534667     Homo sapiens (human)   CLN3 Order cDNA clone, Links
Ceroid-lipofuscinosis, neuronal 3 (CLN3)

Human protein-coding gene CLN3. Represented by 621 ESTs from 252 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 1370981 - Hs.534667]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001035897.1 CLN3 gene product H. sapiens 100.0 437
NP_034037.3 Cln3 gene product M. musculus 91.1 437
NP_001086663.1 ceroid-lipofuscinosis, neuronal 3 X. laevis 65.4 419
NP_001007307.1 cln3 gene product D. rerio 57.8 430
NP_649011.1 cln3, isoform A D. melanogaster 49.1 169
NP_505859.1 human CLN (neuronal ceroid lipofuscinosis) related family member (cln-3.1) C. elegans 48.2 197
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_523328.4 PREDICTED: battenin P. troglodytes 99.4 320
XP_003916786.1 PREDICTED: LOW QUALITY PROTEIN: battenin-like P. anubis 97.7 437

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; uncharacterized tissue; intestine; kidney; mixed; mammary gland; lung; testis; prostate; adrenal gland; bone marrow; blood; vascular; salivary gland; eye; umbilical cord; cervix; connective tissue; uterus; thymus; skin; embryonic tissue; nerve; parathyroid; muscle; ascites; ovary; heart; liver; stomach; pancreas; pituitary gland; bone; spleen; esophagus; lymph node; trachea; lymph; bladder
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p12.1
UniSTS entry: Chr 16 D16S3212 [Map Viewer]
UniSTS entry: Chr 16 RH70509
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (37)

AF015593.1 Homo sapiens CLN3 protein (CLN3) mRNA, complete cds P
AF015595.1 Homo sapiens CLN3 protein (CLN3) mRNA, complete cds P
AF015598.1 Homo sapiens CLN3 protein (CLN3) mRNA, complete cds P
NM_000086.2 Homo sapiens ceroid-lipofuscinosis, neuronal 3 (CLN3), transcript variant 2, mRNA P
AF078169.1 Homo sapiens CLN3 protein (CLN3) mRNA, complete cds P
AF077956.1 Homo sapiens clone 412 CLN3 protein (CLN3) mRNA, complete cds P
AF077957.1 Homo sapiens clone 313 CLN3 protein (CLN3) mRNA, complete cds P
AF077958.1 Homo sapiens clone 301 CLN3 protein (CLN3) mRNA, complete cds P
AF077959.1 Homo sapiens clone 305 CLN3 protein (CLN3) mRNA, complete cds P
AF077960.1 Homo sapiens clone 318 CLN3 protein (CLN3) mRNA, complete cds P
AF077961.1 Homo sapiens clone 327 CLN3 protein (CLN3) mRNA, complete cds P
AF077962.1 Homo sapiens clone 333 CLN3 protein (CLN3) mRNA, complete cds P
AF077966.1 Homo sapiens clone 506 CLN3 protein (CLN3) mRNA, complete cds P
AF077970.1 Homo sapiens clone 517 CLN3 protein (CLN3) mRNA, complete cds P
AF077971.1 Homo sapiens clone 21 CLN3 protein (CLN3) mRNA, complete cds P
AF077972.1 Homo sapiens clone 32 CLN3 protein (CLN3) mRNA, complete cds P
U32680.1 Homo sapiens CLN3 protein (CLN3) mRNA, complete cds P
BC111068.1 Homo sapiens ceroid-lipofuscinosis, neuronal 3, mRNA (cDNA clone MGC:102840 IMAGE:5764535), complete cds PA
BC002394.2 Homo sapiens ceroid-lipofuscinosis, neuronal 3, mRNA (cDNA clone MGC:8415 IMAGE:2820893), complete cds PA
NM_001042432.1 Homo sapiens ceroid-lipofuscinosis, neuronal 3 (CLN3), transcript variant 1, mRNA P
BC004433.1 Homo sapiens ceroid-lipofuscinosis, neuronal 3, mRNA (cDNA clone MGC:3974 IMAGE:2820893), complete cds PA
AK313002.1 Homo sapiens cDNA, FLJ93467, highly similar to Homo sapiens ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) (CLN3), mRNA P
AK090709.1 Homo sapiens cDNA FLJ33390 fis, clone BRACE2006900, highly similar to CLN3 PROTEIN P
AK294250.1 Homo sapiens cDNA FLJ59870 complete cds, highly similar to Protein CLN3 P
AK294070.1 Homo sapiens cDNA FLJ60087 complete cds, highly similar to Protein CLN3 PA
AK297690.1 Homo sapiens cDNA FLJ59353 complete cds, highly similar to Protein CLN3 P
AK295500.1 Homo sapiens cDNA FLJ59896 complete cds, highly similar to Protein CLN3 P
AK302138.1 Homo sapiens cDNA FLJ59098 complete cds, highly similar to Protein CLN3 P
AK302027.1 Homo sapiens cDNA FLJ58551 complete cds, highly similar to Protein CLN3 PA
AF078168.1 Homo sapiens CLN3 protein (CLN3) mRNA, alternative splice product, partial cds P
AF015602.1 Homo sapiens CLN3 protein (CLN3) mRNA, partial cds
AF015601.1 Homo sapiens CLN3 protein (CLN3) mRNA, partial cds P
AF015600.1 Homo sapiens CLN3 protein (CLN3) mRNA, partial cds P
AF015599.1 Homo sapiens CLN3 protein (CLN3) mRNA, partial cds P
AF015597.1 Homo sapiens CLN3 protein (CLN3) mRNA, partial cds P
AF015596.1 Homo sapiens CLN3 protein (CLN3) mRNA, partial cds P
AF015594.1 Homo sapiens CLN3 protein (CLN3) mRNA, partial cds P

EST sequences (10 of 621) [Show all sequences]

AI005583.1 Clone IMAGE:1641541 testis 3' read A
AA948415.1 Clone IMAGE:1560311 intestine 3' read A
AI078485.1 Clone IMAGE:1675254 mixed 3' read PA
AI127905.1 Clone IMAGE:1712673 uterus 3' read A
AI138575.1 Clone IMAGE:1736245 testis 3' read A
CB051234.1 Clone IMAGE:3289346 prostate 3' read PA
CB051235.1 Clone IMAGE:3289346 prostate 5' read P
BX097302.1 Clone IMAGp998D015339_;_IMAGE:2161872 kidney P
AI188631.1 Clone IMAGE:1723808 placenta 3' read PA
AI207235.1 Clone IMAGE:1762137 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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