> SMEK homolog 1, suppressor of mek1 (Dictyostelium) (SMEK1)
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UGID:1293262     UniGene Hs.533887     Homo sapiens (human)   SMEK1 Order cDNA clone, Links
SMEK homolog 1, suppressor of mek1 (Dictyostelium) (SMEK1)

Human protein-coding gene SMEK1. Represented by 303 ESTs from 177 cDNA libraries. Corresponds to reference sequence NM_032560.4. [UniGene 1293262 - Hs.533887]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003902216.1 PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 3A P. anubis 100.0 819
XP_001140788.2 PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 1 P. troglodytes 100.0 819
NP_115949.3 SMEK1 gene product H. sapiens 100.0 819
NP_001153686.1 serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 2 M. musculus 99.9 832
NP_001258103.1 SMEK homolog 1, suppressor of mek1 isoform 1 R. norvegicus 99.9 832
XP_002719645.1 PREDICTED: SMEK homolog 1, suppressor of mek1-like isoform 2 O. cuniculus 99.9 832
XP_854423.1 PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 1 C. lupus familiaris 99.9 819
XP_001928870.1 PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 1 S. scrofa 99.9 819
NP_001192449.1 serine/threonine-protein phosphatase 4 regulatory subunit 3A B. taurus 99.8 819
XP_004017996.1 PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 1 O. aries 99.8 819
NP_001085057.1 serine/threonine-protein phosphatase 4 regulatory subunit 3 X. laevis 95.6 821
NP_001038274.1 serine/threonine-protein phosphatase 4 regulatory subunit 3 D. rerio 93.9 817
NP_731849.2 falafel, isoform B D. melanogaster 69.2 760
NP_001023911.1 Protein SMK-1, isoform c C. elegans 49.7 365
XP_001691599.1 predicted protein C. reinhardtii 46.0 248
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
XP_003339530.1 PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 3A M. domestica 99.3 832
XP_421321.2 PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 3A G. gallus 99.2 820

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; connective tissue; pharynx; thyroid; pancreas; testis; mixed; prostate; liver; eye; bone; adipose tissue; uterus; lung; lymph node; placenta; embryonic tissue; kidney; skin; intestine; mouth; bone marrow; ovary; stomach; blood; mammary gland; adrenal gland; nerve; spleen; pituitary gland; esophagus; thymus; epididymis; larynx; bladder; tonsil; heart; ascites; muscle; cervix; vascular
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q32.12
UniSTS entry: Chr 14 FLJ20707
UniSTS entry: Chr 14 RH78410
UniSTS entry: Chr 14 MARC_16316-16317:1017431376:1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BX248247.1 human full-length cDNA clone CL0BB011ZA10 of Neuroblastoma of Homo sapiens (human) P
BC072409.1 Homo sapiens SMEK homolog 1, suppressor of mek1 (Dictyostelium), mRNA (cDNA clone MGC:87841 IMAGE:6142109), complete cds PA
AK024297.1 Homo sapiens cDNA FLJ14235 fis, clone NT2RP4000167 P
NM_032560.4 Homo sapiens SMEK homolog 1, suppressor of mek1 (Dictyostelium) (SMEK1), mRNA P
BC028088.1 Homo sapiens SMEK homolog 1, suppressor of mek1 (Dictyostelium), mRNA (cDNA clone IMAGE:3462769), partial cds A
AL832921.1 Homo sapiens mRNA; cDNA DKFZp762N0415 (from clone DKFZp762N0415) PA
AF113213.1 Homo sapiens MSTP033 mRNA, complete cds A
BC022778.1 Homo sapiens cDNA clone IMAGE:3916838 PA
BC018617.1 Homo sapiens SMEK homolog 1, suppressor of mek1 (Dictyostelium), mRNA (cDNA clone IMAGE:4853847), with apparent retained intron PA
BC038932.1 Homo sapiens SMEK homolog 1, suppressor of mek1 (Dictyostelium), mRNA (cDNA clone MGC:45056 IMAGE:5579749), complete cds PA
AB095930.1 Homo sapiens mRNA for KIAA2010 protein P

EST sequences (10 of 303) [Show all sequences]

AA902279.1 Clone IMAGE:1519247 uncharacterized tissue 3' read A
AI143952.1 Clone IMAGE:1737677 testis 3' read A
CB051960.1 Clone IMAGE:3290010 uncharacterized tissue 3' read A
CB051961.1 Clone IMAGE:3290010 uncharacterized tissue 5' read P
BX119012.1 Clone IMAGp998J23587_;_IMAGE:267766 skin
AI214039.1 Clone IMAGE:1956749 brain 3' read A
AI219723.1 Clone IMAGE:1842217 mixed 3' read A
AI251116.1 Clone IMAGE:2004765 pancreas 3' read A
CB156944.1 Clone L17N670205n1-6-B04 liver 5' read P
AI276162.1 Clone IMAGE:1878182 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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