> K(lysine) acetyltransferase 8 (KAT8)
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UGID:1293178     UniGene Hs.533803     Homo sapiens (human)   KAT8
K(lysine) acetyltransferase 8 (KAT8)

Human protein-coding gene KAT8. Represented by 195 ESTs from 124 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 1293178 - Hs.533803]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_892003.2 KAT8 gene product H. sapiens 100.0 466
XP_001500799.1 PREDICTED: probable histone acetyltransferase MYST1 E. caballus 100.0 458
XP_003916844.1 PREDICTED: histone acetyltransferase KAT8 P. anubis 100.0 457
XP_003124518.1 PREDICTED: probable histone acetyltransferase MYST1 S. scrofa 100.0 457
XP_002802504.1 PREDICTED: probable histone acetyltransferase MYST1-like M. mulatta 100.0 391
NP_080646.1 Kat8 gene product M. musculus 99.8 457
NP_001017378.1 Kat8 gene product R. norvegicus 99.8 457
XP_536904.2 PREDICTED: histone acetyltransferase KAT8 isoform 1 C. lupus familiaris 99.8 457
NP_001098953.1 KAT8 gene product B. taurus 99.8 457
XP_002721776.1 PREDICTED: MYST histone acetyltransferase 1 O. cuniculus 99.8 457
XP_004020970.1 PREDICTED: histone acetyltransferase KAT8 O. aries 99.6 457
NP_997907.1 kat8 gene product D. rerio 95.1 447
NP_511051.1 males absent on the first D. melanogaster 64.8 446
NP_014887.3 Esa1p S. cerevisiae 63.9 285
NP_504796.1 Protein MYS-1 C. elegans 63.1 290
XP_962217.1 histone acetyltransferase ESA1 N. crassa 62.9 288
NP_001090233.1 MYST histone acetyltransferase 2 X. laevis 62.8 368
XP_001695757.1 MYST family histone acetyltransferase C. reinhardtii 62.0 395
NP_196536.1 MYST-like histone acetyltransferase 2 A. thaliana 62.0 421
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
XP_001372200.1 PREDICTED: probable histone acetyltransferase MYST1 M. domestica 99.3 451
XP_523493.4 PREDICTED: LOW QUALITY PROTEIN: histone acetyltransferase KAT8 P. troglodytes 99.1 455

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lymph node; cervix; stomach; embryonic tissue; placenta; uncharacterized tissue; mammary gland; pancreas; eye; mixed; testis; lung; intestine; ovary; bone marrow; skin; muscle; kidney; larynx; prostate; uterus; ear; heart; liver; blood; salivary gland; nerve; bone; ascites; parathyroid; lymph
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p11.2
UniSTS entry: Chr 16 RH98758
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AL050395.1 Homo sapiens mRNA; cDNA DKFZp586D1020 (from clone DKFZp586D1020) PA
AF260665.2 Homo sapiens histone acetyltransferase (MOF) mRNA, partial cds PA
AK021872.1 Homo sapiens cDNA FLJ11810 fis, clone HEMBA1006347, moderately similar to MALES-ABSENT ON THE FIRST PROTEIN (EC 2.3.1.-) P
AK024102.1 Homo sapiens cDNA FLJ14040 fis, clone HEMBA1005513, weakly similar to MALES-ABSENT ON THE FIRST PROTEIN (EC 2.3.1.-) P
AK225660.1 Homo sapiens mRNA for Splice isoform 2 of Q9H7Z6 variant, clone: STM04995 PA
NM_032188.2 Homo sapiens K(lysine) acetyltransferase 8 (KAT8), transcript variant 1, mRNA PA
NM_182958.2 Homo sapiens K(lysine) acetyltransferase 8 (KAT8), transcript variant 2, mRNA PA
AF217501.1 Homo sapiens histone acetyltransferase MYST1 (MYST1) mRNA, complete cds PA
AK291106.1 Homo sapiens cDNA FLJ78028 complete cds PA
BC037773.1 Homo sapiens MYST histone acetyltransferase 1, mRNA (cDNA clone MGC:41769 IMAGE:5278026), complete cds PA

EST sequences (10 of 195) [Show all sequences]

AA864295.1 Clone IMAGE:1470421 uncharacterized tissue 3' read A
AA977856.1 Clone IMAGE:1590319 kidney 3' read P
AA906593.1 Clone IMAGE:1524230 mixed 3' read P
T26635.1 Clone LLAB376B6 brain 3' read P
AI148913.1 Clone IMAGE:1713944 placenta 3' read P
BX101035.1 Clone IMAGp998M10544_;_IMAGE:251313 skin P
AI167200.1 Clone IMAGE:1509170 mixed 3' read PA
AI217074.1 Clone IMAGE:1732181 heart 3' read P
CB157527.1 Clone L17N670205n1-10-H04 liver 5' read P
CB162275.1 Clone L17N670205n1-19-G03 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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