> H3 histone, family 3A (H3F3A)
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UGID:1292999     UniGene Hs.533624     Homo sapiens (human)   H3F3A Order cDNA clone, Links
H3 histone, family 3A (H3F3A)

Human protein-coding gene H3F3A. Represented by 1815 ESTs from 483 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 1292999 - Hs.533624]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_032236.1 H3f3a gene product M. musculus 100.0 135
NP_446437.1 H3f3b gene product R. norvegicus 100.0 135
XP_002732446.1 PREDICTED: histone H3.3B-like isoform 1 S. kowalevskii 100.0 135
XP_001368225.1 PREDICTED: histone H3.3-like M. domestica 100.0 135
XP_003216117.1 PREDICTED: histone H3.3-like A. carolinensis 100.0 135
XP_003400767.1 PREDICTED: histone H3.3-like B. terrestris 100.0 135
XP_003961353.1 PREDICTED: histone H3.3-like T. rubripes 100.0 135
XP_003386893.1 PREDICTED: histone H3.3-like A. queenslandica 100.0 135
XP_001623766.1 predicted protein N. vectensis 100.0 135
NP_001184227.1 LOC100224650 gene product T. guttata 100.0 135
XP_002154470.1 PREDICTED: histone H3.3-like H. magnipapillata 100.0 135
XP_002579313.1 histone H3 S. mansoni 100.0 135
NP_509344.1 Protein HIS-71 C. elegans 100.0 135
NP_001191424.1 histone 3 A. californica 100.0 135
XP_002399568.1 Core histone H2A/H2B/H3/H4 I. scapularis 100.0 135
XP_001949472.1 PREDICTED: histone H3.3-like A. pisum 100.0 135
XP_975889.1 PREDICTED: similar to Histone H3.3B CG8989-PA isoform 2 T. castaneum 100.0 135
NP_001091756.1 h3 histone family 3a B. mori 100.0 135
XP_001657554.1 histone H3.3 A. aegypti 100.0 135
XP_321242.1 AGAP001813-PA A. gambiae 100.0 135
XP_001867328.1 histone H3.3 type 2 C. quinquefasciatus 100.0 135
NP_511095.1 histone H3.3B, isoform A D. melanogaster 100.0 135
XP_002078203.1 GD23319 D. simulans 100.0 135
XP_001608166.1 PREDICTED: histone H3.3-like isoform 2 N. vitripennis 100.0 135
XP_001120696.1 PREDICTED: histone H3.3-like isoform 1 A. mellifera 100.0 135
XP_791401.1 PREDICTED: histone H3.3-like S. purpuratus 100.0 135
XP_002119783.1 PREDICTED: histone H3.3-like C. intestinalis 100.0 135
XP_002589240.1 hypothetical protein BRAFLDRAFT_120760 B. floridae 100.0 135
XP_002664801.1 PREDICTED: histone H3.3-like isoform 2 D. rerio 100.0 135
XP_004080398.1 PREDICTED: histone H3.3-like O. latipes 100.0 135
XP_003438715.1 PREDICTED: histone H3.3-like O. niloticus 100.0 135
NP_001080065.1 H3 histone, family 3B (H3.3B) X. laevis 100.0 135
XP_002940033.1 PREDICTED: histone H3.3 X. tropicalis 100.0 135
XP_003643522.1 PREDICTED: histone H3.3-like G. gallus 100.0 135
XP_003211494.1 PREDICTED: histone H3.3-like M. gallopavo 100.0 135
XP_001091581.1 PREDICTED: histone H3.3-like isoform 1 M. mulatta 100.0 135
NP_001162389.1 histone H3.1 P. anubis 100.0 135
NP_001092038.1 HIST1H3A gene product P. troglodytes 100.0 135
NP_002098.1 H3F3A gene product H. sapiens 100.0 135
XP_537232.1 PREDICTED: histone H3.3 isoform 1 C. lupus familiaris 100.0 135
XP_001495110.1 PREDICTED: histone H3.3-like isoform 1 E. caballus 100.0 135
XP_003131242.1 PREDICTED: histone H3.3-like S. scrofa 100.0 135
NP_001229500.1 H3F3B gene product B. taurus 100.0 135
XP_004013172.1 PREDICTED: histone H3.3 O. aries 100.0 135
NP_001164583.1 H3.3A gene product O. cuniculus 100.0 135
NP_001078517.1 histone H3 A. thaliana 97.1 135
XP_956003.1 histone H3 N. crassa 96.3 135
NP_009564.1 Hht1p S. cerevisiae 95.6 135
XP_001690671.1 histone H3 C. reinhardtii 95.6 134
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_001514437.1 PREDICTED: histone H3.2-like O. anatinus 98.5 135
XP_002999294.1 histone, putative P. infestans 97.8 135

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uterus; testis; stomach; pancreas; embryonic tissue; liver; mixed; lung; eye; intestine; uncharacterized tissue; blood; placenta; prostate; mammary gland; ovary; bone; skin; bone marrow; muscle; kidney; ascites; epididymis; heart; vascular; esophagus; tonsil; pharynx; thyroid; lymph node; spinal cord; mouth; bladder; ear; spleen; thymus; larynx; cervix; adrenal gland; connective tissue; parathyroid; lymph; pineal gland; pituitary gland; umbilical cord; nerve; adipose tissue; salivary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 1q42.12
UniSTS entry: Chr 17 H3f3a
UniSTS entry: Chr 15 WI-6046
UniSTS entry: Chr 15 D15S1185
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

NM_002107.4 Homo sapiens H3 histone, family 3A (H3F3A), mRNA PA
BC066901.1 Homo sapiens H3 histone, family 3A pseudogene, mRNA (cDNA clone IMAGE:4826805) PA
BC067757.1 Homo sapiens H3 histone, family 3A pseudogene, mRNA (cDNA clone IMAGE:5294551) PA
BC081561.1 Homo sapiens H3 histone, family 3A, mRNA (cDNA clone MGC:87783 IMAGE:5162817), complete cds PA
BC081560.1 Homo sapiens H3 histone, family 3B (H3.3B), mRNA (cDNA clone MGC:87782 IMAGE:3884607), complete cds PA
M11354.1 Human H3.3 histone, class B mRNA, complete cds P
BC095447.1 Homo sapiens H3 histone, family 3A, mRNA (cDNA clone MGC:111189 IMAGE:30718542), complete cds PA
AK291102.1 Homo sapiens cDNA FLJ78487 complete cds, highly similar to Homo sapiens H3 histone, family 3A (H3F3A), mRNA P
AK311905.1 Homo sapiens cDNA, FLJ92171, Homo sapiens H3 histone, family 3A (H3F3A), mRNA P
BC029405.1 Homo sapiens H3 histone, family 3A, mRNA (cDNA clone MGC:32638 IMAGE:4077662), complete cds PA
BC013857.1 Homo sapiens H3 histone, family 3A, mRNA (cDNA clone IMAGE:4519354) PA
NR_002315.1 Homo sapiens H3 histone, family 3A, pseudogene 4 (H3F3AP4), non-coding RNA PA
BC038989.1 Homo sapiens H3 histone, family 3A, mRNA (cDNA clone MGC:47761 IMAGE:6014954), complete cds PA

EST sequences (10 of 1815) [Show all sequences]

AA954892.1 Clone IMAGE:1576263 intestine 3' read P
AA961103.1 Clone IMAGE:1569812 lung 3' read P
AA968765.1 Clone IMAGE:1597444 uncharacterized tissue 3' read
AA971862.1 Clone IMAGE:1584786 lung 3' read P
AA973697.1 Clone IMAGE:1569088 lung 3' read P
AA974043.1 Clone IMAGE:1585490 lung 3' read P
AA989136.1 Clone IMAGE:1593492 kidney 3' read P
AA988848.1 Clone IMAGE:1602061 lung 3' read P
AA995531.1 Clone IMAGE:1606639 kidney 3' read A
AA999691.1 Clone IMAGE:1612906 uncharacterized tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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