> Cystathionine-beta-synthase (CBS)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:1292388     UniGene Hs.533013     Homo sapiens (human)   CBS Order cDNA clone, Links
Cystathionine-beta-synthase (CBS)

Human protein-coding gene CBS. Represented by 452 ESTs from 165 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 1292388 - Hs.533013]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001171479.1 CBS gene product H. sapiens 100.0 550
XP_001143121.1 PREDICTED: cystathionine beta-synthase isoform 10 P. troglodytes 99.8 550
NP_835742.1 Cbs gene product M. musculus 92.3 546
NP_001086820.1 cystathionine-beta-synthase X. laevis 87.0 561
NP_001104702.1 cbsa gene product D. rerio 84.8 565
NP_608424.1 cystathionine beta-synthase, isoform A D. melanogaster 64.2 511
XP_959306.1 cystathionine beta-synthase N. crassa 61.1 525
NP_509686.2 hypothetical protein ZC373.1 C. elegans 59.0 327
NP_011671.3 cystathionine beta-synthase CYS4 S. cerevisiae 56.5 437
NP_181903.1 cysteine synthase A. thaliana 46.8 203
XP_001691936.1 cysteine synthase C. reinhardtii 45.8 216
Other hits (2 of 59) [Show all]SpeciesId(%)Len(aa)
XP_003895474.1 PREDICTED: cystathionine beta-synthase isoform 1 P. anubis 98.4 550
XP_004003421.1 PREDICTED: cystathionine beta-synthase isoform 2 O. aries 93.0 570

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; eye; lymph; lung; liver; muscle; prostate; uncharacterized tissue; ovary; pancreas; mixed; blood; mouth; trachea; epididymis; intestine; connective tissue; spleen; pituitary gland; placenta; cervix; esophagus; bladder; uterus; skin; stomach; mammary gland; nerve; testis; amniotic fluid; bone; kidney; thyroid; ganglia; vascular; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q22.3
UniSTS entry: Chr 21 GDB:192314
UniSTS entry: Chr 21 RH78946 [Map Viewer]
UniSTS entry: Chr 21 D21S271E [Map Viewer]
UniSTS entry: Chr 21 GDB:185174
UniSTS entry: Chr 21 SGC35805 [Map Viewer]
UniSTS entry: Chr 21 D21S271E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BT007154.1 Homo sapiens cystathionine-beta-synthase mRNA, complete cds P
NM_000071.2 Homo sapiens cystathionine-beta-synthase (CBS), transcript variant 1, mRNA PA
AL137314.1 Homo sapiens mRNA; cDNA DKFZp727E011 (from clone DKFZp727E011); partial cds PA
BC000440.2 Homo sapiens cystathionine-beta-synthase, mRNA (cDNA clone MGC:8402 IMAGE:2820694), complete cds PA
BC007257.1 Homo sapiens cystathionine-beta-synthase, mRNA (cDNA clone MGC:15515 IMAGE:3028099), complete cds PA
BC012319.1 Homo sapiens, clone IMAGE:3608784, mRNA, partial cds PA
BC011381.1 Homo sapiens cystathionine-beta-synthase, mRNA (cDNA clone MGC:17143 IMAGE:3869615), complete cds PA
BC010242.1 Homo sapiens cystathionine-beta-synthase, mRNA (cDNA clone MGC:18160 IMAGE:4154798), complete cds PA
AK313691.1 Homo sapiens cDNA, FLJ94281, Homo sapiens cystathionine-beta-synthase (CBS), mRNA P
AK301063.1 Homo sapiens cDNA FLJ53928 complete cds, highly similar to Cystathionine beta-synthase (EC 4.2.1.22) P
AK294608.1 Homo sapiens cDNA FLJ53863 complete cds, highly similar to Cystathionine beta-synthase (EC 4.2.1.22) P
L14577.1 Homo sapiens cystathionine beta-synthase (CBS) mRNA, complete cds P
L00972.1 Human cystathionine-beta-synthase (CBS) mRNA PA
NM_001178009.1 Homo sapiens cystathionine-beta-synthase (CBS), transcript variant 3, mRNA PA
NM_001178008.1 Homo sapiens cystathionine-beta-synthase (CBS), transcript variant 2, mRNA PA
X82166.1 H.sapiens mRNA for cystathionine-beta-synthase PA
L19501.1 Homo sapiens (clone pGHSCBS) cystathionine beta-synthase subunit (CBS) mRNA, complete cds PA

EST sequences (10 of 452) [Show all sequences]

AA866043.1 Clone IMAGE:1470298 uncharacterized tissue 3' read A
AA995138.1 Clone IMAGE:1627001 mixed 3' read
AA921824.1 Clone IMAGE:1543858 mixed 3' read
AI053744.1 Clone IMAGE:1861795 ovary 3' read A
AI088293.1 Clone IMAGE:1690844 mixed 3' read
BX101034.1 Clone IMAGp998A04528_;_IMAGE:244875 mixed
BX117844.1 Clone IMAGp998O044969_;_IMAGE:2020059 brain
AI266220.1 Clone IMAGE:1932339 mixed 3' read
CB162708.1 Clone L17N670205n1-30-D06 liver 5' read P
CB162829.1 Clone L17N670205n1-31-H09 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help