> Inositol polyphosphate-4-phosphatase, type II, 105kDa (INPP4B)
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UGID:1231193     UniGene Hs.531403     Homo sapiens (human)   INPP4B
Inositol polyphosphate-4-phosphatase, type II, 105kDa (INPP4B)

Human protein-coding gene INPP4B. Represented by 158 ESTs from 89 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 1231193 - Hs.531403]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003857.2 INPP4B gene product H. sapiens 100.0 923
XP_001141569.1 PREDICTED: type II inositol-3,4-bisphosphate 4-phosphatase isoform 3 P. troglodytes 99.9 923
NP_001019788.1 Inpp4b gene product M. musculus 94.4 923
NP_001139046.1 type II inositol-3,4-bisphosphate 4-phosphatase D. rerio 66.6 822
NP_001089588.1 inositol polyphosphate-4-phosphatase, type I, 107kDa X. laevis 53.6 893
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_001091997.1 PREDICTED: type II inositol-3,4-bisphosphate 4-phosphatase isoform 4 M. mulatta 99.3 923
XP_003899268.1 PREDICTED: type II inositol 3,4-bisphosphate 4-phosphatase-like, partial P. anubis 99.3 770

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mammary gland; skin; testis; mixed; muscle; lung; kidney; uncharacterized tissue; bone marrow; prostate; intestine; esophagus; uterus; liver; trachea; connective tissue; stomach; umbilical cord; lymph node; pancreas; heart; vascular; bone; bladder; embryonic tissue; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q31.21
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

BX649090.1 Homo sapiens mRNA; cDNA DKFZp779P1062 (from clone DKFZp779P1062) PA
AK126441.1 Homo sapiens cDNA FLJ44477 fis, clone UTERU2031703
NM_003866.2 Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kDa (INPP4B), transcript variant 1, mRNA PA
BC072447.1 Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kDa, mRNA (cDNA clone IMAGE:6165861), partial cds PA
AY753912.1 Homo sapiens inositol polyphosphate 4-phosphatase type II-stubby transcript variant c (INPP4B) mRNA, complete cds, alternatively spliced P
BC110918.1 Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kDa, mRNA (cDNA clone MGC:132014 IMAGE:6160633), complete cds PA
BC005273.1 Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kDa, mRNA (cDNA clone IMAGE:3685423), complete cds A
BC133005.1 Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kDa, mRNA (cDNA clone MGC:164636 IMAGE:40147027), complete cds P
NM_001101669.1 Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kDa (INPP4B), transcript variant 2, mRNA PA
BC017924.2 Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kDa, mRNA (cDNA clone IMAGE:4249398), partial cds PA
BC005274.1 Homo sapiens inositol polyphosphate-4-phosphatase, type II, 105kDa, mRNA (cDNA clone IMAGE:3932953) PA
BC144255.1 Homo sapiens cDNA clone IMAGE:9052775 PA
AK302936.1 Homo sapiens cDNA FLJ60998 complete cds, highly similar to Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) P
AK300891.1 Homo sapiens cDNA FLJ50877 partial cds, highly similar to Type II inositol-3,4-bisphosphate4-phosphatase (EC 3.1.3.66) P
AK298118.1 Homo sapiens cDNA FLJ51916 complete cds, highly similar to Type II inositol-3,4-bisphosphate4-phosphatase (EC 3.1.3.66) P
U96922.1 Homo sapiens inositol polyphosphate 4-phosphatase type II-alpha mRNA, complete cds P

EST sequences (10 of 158) [Show all sequences]

AI039236.1 Clone IMAGE:1658062 embryonic tissue 3' read PA
AI140811.1 Clone IMAGE:1566242 mixed 3' read PA
BX101401.1 Clone IMAGp998C136131_;_IMAGE:2464836 lung
AI167435.1 Clone IMAGE:1661732 mixed 3' read P
BX117295.1 Clone IMAGp998A125707_;_IMAGE:2303123 uncharacterized tissue
BX097835.1 Clone IMAGp998N102008_;_IMAGE:813513 mixed PA
CB159905.1 Clone L18POOL1n1-43-D09 liver 5' read P
AI282163.1 Clone IMAGE:1927810 lung 3' read P
AI379943.1 Clone IMAGE:2068329 mixed 3' read
AI570859.1 Clone IMAGE:2223443 pancreas 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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