> Chromodomain helicase DNA binding protein 8 (CHD8)
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UGID:1204965     UniGene Hs.530698     Homo sapiens (human)   CHD8 Links
Chromodomain helicase DNA binding protein 8 (CHD8)

Human protein-coding gene CHD8. Represented by 375 ESTs from 199 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 1204965 - Hs.530698]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003314292.1 PREDICTED: chromodomain-helicase-DNA-binding protein 8 P. troglodytes 100.0 2580
NP_001164100.1 CHD8 gene product H. sapiens 100.0 2580
XP_001096619.2 PREDICTED: chromodomain-helicase-DNA-binding protein 8-like M. mulatta 99.9 2300
XP_003901583.1 PREDICTED: chromodomain-helicase-DNA-binding protein 8 isoform 1 P. anubis 99.8 2580
NP_963999.2 Chd8 gene product M. musculus 98.0 2581
NP_001189381.1 chd8 gene product D. rerio 71.1 2548
NP_491426.2 Protein CHD-7 C. elegans 62.8 985
NP_001245818.1 kismet, isoform D D. melanogaster 62.2 1390
XP_956548.2 chromatin remodelling complex ATPase chain ISW1 N. crassa 55.0 289
NP_011091.1 Chd1p S. cerevisiae 50.8 451
NP_001189826.1 chromatin-remodeling protein 11 A. thaliana 50.7 438
XP_001691025.1 SNF2 superfamily protein C. reinhardtii 50.0 372
NP_001083868.1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 X. laevis 48.2 388
Other hits (2 of 61) [Show all]SpeciesId(%)Len(aa)
XP_003482311.1 PREDICTED: chromodomain-helicase-DNA-binding protein 8, partial S. scrofa 99.5 2566
NP_001179063.1 chromodomain-helicase-DNA-binding protein 8 B. taurus 99.5 2302

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; blood; tonsil; bladder; ascites; lung; larynx; spleen; embryonic tissue; thyroid; prostate; uncharacterized tissue; amniotic fluid; mixed; muscle; connective tissue; testis; eye; kidney; mammary gland; pituitary gland; skin; cervix; liver; intestine; stomach; uterus; lymph node; placenta; bone marrow; lymph; pancreas; mouth; heart; thymus; bone; trachea; ovary; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q11.2
UniSTS entry: Chr 14 G20455
UniSTS entry: Chr 14 A005R45
UniSTS entry: Chr 14 WI-20203 [Map Viewer]
UniSTS entry: Chr 14 A004V16 [Map Viewer]
UniSTS entry: Chr 14 WI-14045 [Map Viewer]
UniSTS entry: Chr 14 BE589327
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AK122910.1 Homo sapiens cDNA FLJ16585 fis, clone TESTI4000134, weakly similar to Chromodomain helicase-DNA-binding protein Mi-2 P
AK122868.1 Homo sapiens cDNA FLJ16499 fis, clone FCBBF3025650, moderately similar to Drosophila melanogaster KISMET-L long isoform (kis) mRNA P
AK131077.1 Homo sapiens mRNA for FLJ00266 protein P
BC063693.1 Homo sapiens chromodomain helicase DNA binding protein 8, mRNA (cDNA clone IMAGE:4443191), partial cds PA
BC073903.1 Homo sapiens chromodomain helicase DNA binding protein 8, mRNA (cDNA clone IMAGE:4415955), partial cds PA
CR749315.1 Homo sapiens mRNA; cDNA DKFZp686N17164 (from clone DKFZp686N17164) PA
NM_020920.3 Homo sapiens chromodomain helicase DNA binding protein 8 (CHD8), transcript variant 2, mRNA PA
BC098452.1 Homo sapiens chromodomain helicase DNA binding protein 8, mRNA (cDNA clone IMAGE:6302978), partial cds PA
AB046784.3 Homo sapiens mRNA for KIAA1564 protein, partial cds P
BC011695.2 Homo sapiens chromodomain helicase DNA binding protein 8, mRNA (cDNA clone IMAGE:3534143), partial cds PA
AK056639.1 Homo sapiens cDNA FLJ32077 fis, clone OCBBF1000188, weakly similar to Drosophila melanogaster KISMET-L long isoform (kis) mRNA P
BC025964.1 Homo sapiens chromodomain helicase DNA binding protein 8, mRNA (cDNA clone IMAGE:3534141), partial cds PA
AK098408.1 Homo sapiens cDNA FLJ25542 fis, clone JTH01318 P
AL834524.1 Homo sapiens mRNA; cDNA DKFZp667O149 (from clone DKFZp667O149) PA
BC036920.1 Homo sapiens chromodomain helicase DNA binding protein 8, mRNA (cDNA clone IMAGE:5199722), partial cds PA
NM_001170629.1 Homo sapiens chromodomain helicase DNA binding protein 8 (CHD8), transcript variant 1, mRNA PA
U00930.1 Human clone C4E 1.63 (CAC)n/(GTG)n repeat-containing mRNA P
U00955.1 Human clone CE29 8.1 (CAC)n/(GTG)n repeat-containing mRNA P
BC040636.1 Homo sapiens, clone IMAGE:4153069, mRNA PA

EST sequences (10 of 375) [Show all sequences]

AA906121.1 Clone IMAGE:1505850 mixed 3' read
AA976744.1 Clone IMAGE:1585816 uncharacterized tissue 3' read P
AI123941.1 Clone IMAGE:1688984 mixed 3' read P
AI083536.1 Clone IMAGE:1662518 mixed 3' read P
CB043941.1 Clone IMAGE:3217660 intestine 3' read PA
CB043942.1 Clone IMAGE:3217660 intestine 5' read P
BX100654.1 Clone IMAGp998I11171_;_IMAGE:40244 brain PA
AI220086.1 Clone IMAGE:1842380 mixed 3' read A
CB162506.1 Clone L17N670205n1-24-F10 liver 5' read P
CB112924.1 Clone L6ChoCK0-10-B08 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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