> NCK adaptor protein 2 (NCK2)
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UGID:1203511     UniGene Hs.529244     Homo sapiens (human)   NCK2 Order cDNA clone, Links
NCK adaptor protein 2 (NCK2)

Human protein-coding gene NCK2. Represented by 251 ESTs from 110 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 1203511 - Hs.529244]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001109452.2 PREDICTED: cytoplasmic protein NCK2 isoform 1 M. mulatta 100.0 381
XP_003909129.1 PREDICTED: cytoplasmic protein NCK2 P. anubis 100.0 381
XP_003309222.1 PREDICTED: cytoplasmic protein NCK2 isoform 1 P. troglodytes 100.0 379
NP_003572.2 NCK2 gene product H. sapiens 100.0 379
NP_035009.3 Nck2 gene product M. musculus 97.6 379
NP_001083313.1 Grb4 adaptor protein X. laevis 88.2 380
NP_001003492.2 nck2b gene product D. rerio 87.6 379
NP_508707.1 Protein NCK-1, isoform b C. elegans 45.8 179
NP_476976.1 dreadlocks, isoform A D. melanogaster 45.0 211
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
XP_001488099.1 PREDICTED: cytoplasmic protein NCK2 E. caballus 99.5 379
XP_538440.2 PREDICTED: cytoplasmic protein NCK2 C. lupus familiaris 99.0 379

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: skin; placenta; brain; lymph node; thyroid; mixed; pancreas; eye; uterus; uncharacterized tissue; cervix; lung; kidney; testis; ovary; embryonic tissue; stomach; mammary gland; intestine; spleen; liver; connective tissue; tonsil; salivary gland; heart; bone; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q12
UniSTS entry: Chr 2 RH68373 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AF047487.1 Homo sapiens Nck-2 (NCK2) mRNA, complete cds P
NM_003581.4 Homo sapiens NCK adaptor protein 2 (NCK2), transcript variant 1, mRNA PA
NM_001004722.3 Homo sapiens NCK adaptor protein 2 (NCK2), transcript variant 3, mRNA PA
NM_001004720.2 Homo sapiens NCK adaptor protein 2 (NCK2), transcript variant 2, mRNA PA
BC000103.2 Homo sapiens NCK adaptor protein 2, mRNA (cDNA clone MGC:1698 IMAGE:3505427), complete cds PA
BC007195.1 Homo sapiens NCK adaptor protein 2, mRNA (cDNA clone MGC:10780 IMAGE:3608149), complete cds PA
BC033176.1 Homo sapiens NCK adaptor protein 2, mRNA (cDNA clone IMAGE:4563278), with apparent retained intron A
AF043119.1 Homo sapiens SH2/SH3 adaptor protein NCK-beta (hNCK-beta) mRNA, complete cds P

EST sequences (10 of 251) [Show all sequences]

AA968620.1 Clone IMAGE:1578360 mixed 3' read A
AI005362.1 Clone IMAGE:1632255 mammary gland 3' read A
AI024746.1 Clone IMAGE:1643286 testis 3' read A
AI041714.1 Clone IMAGE:1660400 mixed 3' read A
AI049541.1 Clone IMAGE:1700160 kidney 3' read A
AI095063.1 Clone IMAGE:1686346 brain 3' read A
AI142886.1 Clone IMAGE:1678250 mixed 3' read A
AI144486.1 Clone IMAGE:1705757 heart 3' read A
CB051830.1 Clone IMAGE:3289846 uncharacterized tissue 3' read A
CB051831.1 Clone IMAGE:3289846 uncharacterized tissue 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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