> Complement component 3 (C3)
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UGID:1203320     UniGene Hs.529053     Homo sapiens (human)   C3 Order cDNA clone, Links
Complement component 3 (C3)

Human protein-coding gene C3. Represented by 1408 ESTs from 339 cDNA libraries. Corresponds to reference sequence NM_000064.2. [UniGene 1203320 - Hs.529053]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000055.2 C3 gene product H. sapiens 100.0 1662
NP_033908.2 C3 gene product M. musculus 81.7 1662
NP_001082701.1 complement C3 X. laevis 55.9 509
XP_002660624.2 PREDICTED: complement C3 D. rerio 49.7 1581
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_512318.4 PREDICTED: complement C3, partial P. troglodytes 99.0 1036
XP_003914815.1 PREDICTED: complement C3 P. anubis 96.8 1662

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: liver; ovary; mammary gland; mixed; lung; uncharacterized tissue; brain; uterus; thyroid; stomach; pancreas; intestine; kidney; testis; adipose tissue; eye; prostate; blood; placenta; bladder; pharynx; bone; skin; mouth; spleen; amniotic fluid; larynx; connective tissue; spinal cord; nerve; cervix; adrenal gland; heart; lymph node; bone marrow; esophagus; thymus; ganglia; trachea; embryonic tissue; muscle; parathyroid; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3-p13.2
UniSTS entry: Chr 19 RH11718
UniSTS entry: Chr 19 RH45403
UniSTS entry: Chr 19 SGC31874 [Map Viewer]
UniSTS entry: Chr 19 GDB:177904
UniSTS entry: Chr 19 RH80210
UniSTS entry: Chr 3 Fgf8
UniSTS entry: Chr 1 D16S325
UniSTS entry: Chr 6 RH15772
UniSTS entry: C3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_000064.2 Homo sapiens complement component 3 (C3), mRNA P
BC063852.1 Homo sapiens cDNA clone IMAGE:6184508, containing frame-shift errors PA
K02765.1 Human complement component C3 mRNA, alpha and beta subunits, complete cds P
AY927485.1 Homo sapiens mRNA sequence
BC150299.1 Homo sapiens cDNA clone IMAGE:8860379, containing frame-shift errors PA
BC150179.1 Homo sapiens complement component 3, mRNA (cDNA clone MGC:164898 IMAGE:40148091), complete cds PA
BC150200.1 Homo sapiens complement component 3, mRNA (cDNA clone MGC:165040 IMAGE:40148812), complete cds PA
AK094728.1 Homo sapiens cDNA FLJ37409 fis, clone BRAMY2028516, highly similar to COMPLEMENT C3 PRECURSOR P
AK304071.1 Homo sapiens cDNA FLJ57339 complete cds, highly similar to Complement C3 precursor P
BC022897.1 Homo sapiens cDNA clone IMAGE:4714760, containing frame-shift errors PA

EST sequences (10 of 1408) [Show all sequences]

AA922356.1 Clone IMAGE:1486309 mouth 3' read P
AA970485.1 Clone IMAGE:1574807 kidney 3' read P
AA972210.1 Clone IMAGE:1582868 mixed 3' read P
AA977976.1 Clone IMAGE:1592355 kidney 3' read
AA987863.1 Clone IMAGE:1592776 kidney 3' read
AA991219.1 Clone IMAGE:1606337 kidney 3' read P
AI000782.1 Clone IMAGE:1613825 uncharacterized tissue 3' read
AA838455.1 Clone IMAGE:1422580 kidney PA
AA887516.1 Clone IMAGE:1500513 lung 3' read P
AA906824.1 Clone IMAGE:1519610 uncharacterized tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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