Ubiquinol-cytochrome c reductase core protein II (UQCRC2)

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UGID:1203070 UniGene Hs.528803 Homo sapiens (human) UQCRC2

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Ubiquinol-cytochrome c reductase core protein II (UQCRC2)

Human protein-coding gene UQCRC2. Represented by 1740 ESTs from 500 cDNA libraries. Corresponds to reference sequence NM_003366.2. [UniGene 1203070 - Hs.528803]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_003357.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	UQCRC2 gene product	H. sapiens	100.0	452
NP_001233459.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	UQCRC2 gene product	P. troglodytes	99.8	452
NP_080175.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	cytochrome b-c1 complex subunit 2, mitochondrial precursor	M. musculus	88.5	452
NP_001086687.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ubiquinol-cytochrome c reductase core protein II	X. laevis	76.0	450
NP_001001589.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	uqcrc2b gene product	D. rerio	68.6	448
Other hits (2 of 21) [Show all]		Species	Id(%)	Len(aa)
XP_001092339.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cytochrome b-c1 complex subunit 2, mitochondrial isoform 3	M. mulatta	98.9	452
XP_003916699.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: cytochrome b-c1 complex subunit 2, mitochondrial-like	P. anubis	98.5	452

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; heart; intestine; uncharacterized tissue; lung; uterus; liver; eye; placenta; testis; embryonic tissue; kidney; stomach; prostate; pancreas; mammary gland; muscle; mixed; skin; blood; pharynx; bone; trachea; epididymis; larynx; nerve; tonsil; salivary gland; ascites; thymus; vascular; connective tissue; bone marrow; mouth; ovary; lymph node; thyroid; cervix; parathyroid; adrenal gland; esophagus; lymph; umbilical cord; spleen; adipose tissue; ear; pituitary gland; bladder; ganglia; spinal cord; amniotic fluid

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	16
Map position:	16p12
UniSTS entry:	Chr 16	RH65269
UniSTS entry:	Chr 16	SHGC-61151	[Map Viewer]
UniSTS entry:		STS-J04973
UniSTS entry:	Chr 16	D16S2552E
UniSTS entry:	Chr 16	SHGC-60745	[Map Viewer]
UniSTS entry:	Chr 15	Rnu2
UniSTS entry:	Chr 16	SHGC-52911

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_003366.2	Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), nuclear gene encoding mitochondrial protein, mRNA	P
BC000484.2	Homo sapiens ubiquinol-cytochrome c reductase core protein II, mRNA (cDNA clone MGC:8349 IMAGE:2819755), complete cds	PA
BC003136.1	Homo sapiens ubiquinol-cytochrome c reductase core protein II, mRNA (cDNA clone MGC:3638 IMAGE:2906230), complete cds	PA
AK307535.1	Homo sapiens cDNA, FLJ97483	P
AK094006.1	Homo sapiens cDNA FLJ36687 fis, clone UTERU2008085, highly similar to Ubiquinol-cytochrome-c reductase complex coreprotein 2, mitochondrial precursor (EC 1.10.2.2)	P
AK093106.1	Homo sapiens cDNA FLJ35787 fis, clone TESTI2005672, highly similar to UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX CORE PROTEIN 2 PRECURSOR (EC 1.10.2.2)	P
J04973.1	Human cytochrome bc-1 complex core protein II mRNA, complete cds	P

EST sequences (10 of 1740) [Show all sequences]

AA975719.1	Clone IMAGE:1591084	kidney	3' read	PA
AA984602.1	Clone IMAGE:1630305	brain	3' read	P
AA988902.1	Clone IMAGE:1602221	lung	3' read	P
AA994837.1	Clone IMAGE:1632026	mammary gland	3' read	PA
AI000339.1	Clone IMAGE:1637000	kidney	3' read	P
T05651.1	Clone HFBDD76	brain
AA923532.1	Clone IMAGE:1536187	kidney	3' read	PA
AI016539.1	Clone IMAGE:1622380	embryonic tissue	3' read	PA
R18857.1	Clone IMAGE:27047	brain	5' read	P
AI038659.1	Clone IMAGE:1658715	embryonic tissue	3' read	PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria