> Histidyl-tRNA synthetase (HARS)
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UGID:1097000     UniGene Hs.528050     Homo sapiens (human)   HARS Order cDNA clone, Links
Histidyl-tRNA synthetase (HARS)

Human protein-coding gene HARS. Represented by 914 ESTs from 316 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 1097000 - Hs.528050]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001233308.1 HARS gene product P. troglodytes 100.0 508
NP_002100.2 HARS gene product H. sapiens 100.0 508
XP_003900262.1 PREDICTED: histidine--tRNA ligase, cytoplasmic isoform 1 P. anubis 99.8 508
NP_032240.3 Hars gene product M. musculus 97.2 508
NP_001004586.1 hars gene product D. rerio 86.1 410
NP_728180.1 Histidyl-tRNA synthetase, isoform A D. melanogaster 73.1 520
NP_001023373.1 Histidyl tRNA Synthetase family member (hrs-1) C. elegans 65.7 513
NP_186925.4 histidyl-tRNA synthetase A. thaliana 64.7 518
XP_959261.1 histidyl-tRNA synthetase, mitochondrial precursor N. crassa 64.3 476
NP_015358.1 histidine--tRNA ligase S. cerevisiae 63.6 530
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_001504203.1 PREDICTED: histidyl-tRNA synthetase, cytoplasmic-like isoform 1 E. caballus 98.2 508
XP_004008921.1 PREDICTED: histidine--tRNA ligase, cytoplasmic isoform 1 O. aries 98.0 508

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; skin; lung; uterus; kidney; intestine; uncharacterized tissue; thyroid; larynx; placenta; muscle; spleen; thymus; eye; stomach; liver; embryonic tissue; mammary gland; prostate; pituitary gland; blood; connective tissue; bladder; cervix; adrenal gland; ovary; pancreas; heart; mixed; vascular; ascites; lymph; esophagus; lymph node; bone marrow; salivary gland; ganglia; tonsil; bone; umbilical cord; ear
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q31.3
UniSTS entry: Chr 5 RH70258 [Map Viewer]
UniSTS entry: Chr 5 Hars
UniSTS entry: Chr 5 WI-19187 [Map Viewer]
UniSTS entry: Chr 5 D5S2775
UniSTS entry: Chr 5 D5S1691E
UniSTS entry: Chr 1 GDB:631802
UniSTS entry: Chr 1 PMC55343P6
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

NM_002109.4 Homo sapiens histidyl-tRNA synthetase (HARS), transcript variant 1, mRNA PA
AK000498.1 Homo sapiens cDNA FLJ20491 fis, clone KAT08396, highly similar to SYH_HUMAN HISTIDYL-TRNA SYNTHETASE PA
BC080514.1 Homo sapiens histidyl-tRNA synthetase, mRNA (cDNA clone MGC:99562 IMAGE:2821065), complete cds PA
AY995220.1 Homo sapiens histidyl-tRNA synthetase (HRS) mRNA, complete cds P
AK225776.1 Homo sapiens mRNA for histidyl-tRNA synthetase variant, clone: FCC132E05 PA
BC011807.2 Homo sapiens histidyl-tRNA synthetase, mRNA (cDNA clone MGC:19592 IMAGE:4331277), complete cds PA
AK307669.1 Homo sapiens cDNA, FLJ97617 P
AK094406.1 Homo sapiens cDNA FLJ37087 fis, clone BRACE2017108
AK293154.1 Homo sapiens cDNA FLJ53703 complete cds, highly similar to Histidyl-tRNA synthetase (EC 6.1.1.21) P
AK293531.1 Homo sapiens cDNA FLJ59476 complete cds, highly similar to Histidyl-tRNA synthetase (EC 6.1.1.21) P
AK303778.1 Homo sapiens cDNA FLJ58562 complete cds, highly similar to Histidyl-tRNA synthetase (EC 6.1.1.21) PA
AK295219.1 Homo sapiens cDNA FLJ53452 complete cds, highly similar to Histidyl-tRNA synthetase (EC 6.1.1.21) PA
AK302295.1 Homo sapiens cDNA FLJ58554 complete cds, highly similar to Histidyl-tRNA synthetase (EC 6.1.1.21) P
NM_001258041.1 Homo sapiens histidyl-tRNA synthetase (HARS), transcript variant 3, mRNA PA
NM_001258042.1 Homo sapiens histidyl-tRNA synthetase (HARS), transcript variant 4, mRNA PA
NM_001258040.1 Homo sapiens histidyl-tRNA synthetase (HARS), transcript variant 2, mRNA PA

EST sequences (10 of 914) [Show all sequences]

AA984229.1 Clone IMAGE:1629650 brain 3' read P
AA984841.1 Clone IMAGE:1630707 brain 3' read P
AA989347.1 Clone IMAGE:1607068 mammary gland 3' read PA
AI077850.1 Clone IMAGE:1665489 skin 3' read A
AI251896.1 Clone IMAGE:1977921 brain 3' read A
CB148142.1 Clone L16HLK3-2-E06 liver 5' read PA
CB159856.1 Clone L18POOL1n1-19-G09 liver 5' read P
CB113653.1 Clone L5HLK1-15-A06 liver 5' read P
CB119906.1 Clone L8SCK0-39-B07 liver 5' read
CB121981.1 Clone L8SCK0-15-C10 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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