> N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1)
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UGID:1087613     UniGene Hs.527412     Homo sapiens (human)   ASAH1 Order cDNA clone, Links
N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1)

Human protein-coding gene ASAH1. Represented by 1745 ESTs from 399 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 1087613 - Hs.527412]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004306.3 ASAH1 gene product H. sapiens 100.0 410
NP_001092030.1 ASAH1 gene product P. troglodytes 99.8 394
NP_062708.1 Asah1 gene product M. musculus 93.4 393
NP_001087503.1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 precursor X. laevis 72.4 394
NP_956871.1 asah1b gene product D. rerio 68.1 394
NP_493173.1 Protein ASAH-1 C. elegans 47.6 187
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_003902522.1 PREDICTED: acid ceramidase-like, partial P. anubis 97.6 293
XP_001098236.1 PREDICTED: acid ceramidase isoform 1 M. mulatta 97.1 410

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; stomach; uncharacterized tissue; kidney; prostate; placenta; blood; lung; mixed; uterus; testis; mammary gland; heart; spleen; skin; liver; intestine; connective tissue; mouth; vascular; eye; pancreas; trachea; thyroid; bladder; pharynx; bone marrow; pituitary gland; muscle; embryonic tissue; adrenal gland; esophagus; bone; larynx; thymus; parathyroid; amniotic fluid; cervix; adipose tissue; lymph node; lymph; ascites; nerve; ovary; salivary gland; pineal gland; spinal cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8p22
UniSTS entry: Chr 8 D8S2114
UniSTS entry: Chr 8 D8S2080 [Map Viewer]
UniSTS entry: Chr 8 D8S1586
UniSTS entry: Chr 8 D8S1341E
UniSTS entry: Chr 8 RH11700
UniSTS entry: Chr 8 RH94375
UniSTS entry: Chr 1 G35510
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 15 Rnu2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

NM_177924.3 Homo sapiens N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1), transcript variant 1, mRNA P
NM_004315.4 Homo sapiens N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1), transcript variant 2, mRNA P
AY305384.1 Homo sapiens HSD-33 mRNA, complete cds P
AK222780.1 Homo sapiens mRNA for N-acylsphingosine amidohydrolase (acid ceramidase) 1 preproprotein isoform a variant, clone: HEP00906 P
AK025732.1 Homo sapiens cDNA: FLJ22079 fis, clone HEP13180, highly similar to HSU70063 Human acid ceramidase mRNA PA
U47674.1 Homo sapiens putative heart protein PHP mRNA, complete cds PA
BC016828.1 Homo sapiens N-acylsphingosine amidohydrolase (acid ceramidase) 1, mRNA (cDNA clone MGC:24572 IMAGE:4109317), complete cds PA
BC016481.1 Homo sapiens N-acylsphingosine amidohydrolase (acid ceramidase) 1, mRNA (cDNA clone MGC:9327 IMAGE:3923451), complete cds PA
AK289481.1 Homo sapiens cDNA FLJ77858 complete cds, highly similar to Homo sapiens N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1), transcript variant 1, mRNA P
NM_001127505.1 Homo sapiens N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1), transcript variant 3, mRNA P
AK098299.1 Homo sapiens cDNA FLJ40980 fis, clone UTERU2014464, highly similar to ACID CERAMIDASE PRECURSOR (EC 3.5.1.23) P
BC035453.1 Homo sapiens N-acylsphingosine amidohydrolase (acid ceramidase) 1, mRNA (cDNA clone IMAGE:3918355) PA
U70063.1 Human acid ceramidase mRNA, complete cds PA

EST sequences (10 of 1745) [Show all sequences]

AA961204.1 Clone IMAGE:1569821 lung 3' read A
R14420.1 Clone IMAGE:29052 brain 5' read
AA984467.1 Clone IMAGE:1630072 brain 3' read
AA987965.1 Clone IMAGE:1603454 lung 3' read P
R19013.1 Clone IMAGE:33410 brain 5' read
AA927968.1 Clone IMAGE:1559800 intestine 3' read A
AI040424.1 Clone IMAGE:1646972 parathyroid 3' read A
R20765.1 Clone IMAGE:26516 brain 3' read A
AI089376.1 Clone IMAGE:1695790 uterus 3' read A
AI096608.1 Clone IMAGE:1703011 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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