> Malate dehydrogenase 1, NAD (soluble) (MDH1)
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UGID:1086722     UniGene Hs.526521     Homo sapiens (human)   MDH1 Order cDNA clone, Links
Malate dehydrogenase 1, NAD (soluble) (MDH1)

Human protein-coding gene MDH1. Represented by 1617 ESTs from 386 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 1086722 - Hs.526521]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001186040.1 MDH1 gene product H. sapiens 100.0 351
NP_001229997.1 malate dehydrogenase, cytoplasmic isoform 1 P. troglodytes 99.7 351
XP_001084973.1 PREDICTED: malate dehydrogenase, cytoplasmic isoform 3 M. mulatta 99.7 339
NP_032644.3 Mdh1 gene product M. musculus 99.7 333
XP_003908769.1 PREDICTED: malate dehydrogenase, cytoplasmic-like P. anubis 99.7 333
NP_001083335.1 malate dehydrogenase, cytoplasmic X. laevis 92.8 333
NP_956263.1 mdh1b gene product D. rerio 85.8 331
NP_609394.1 malate dehydrogenase 1 D. melanogaster 72.3 332
NP_504656.1 Protein MDH-1, isoform a C. elegans 68.3 334
NP_171936.1 malate dehydrogenase A. thaliana 67.8 328
XP_001694886.1 NAD-dependent malate dehydrogenase C. reinhardtii 63.2 299
Other hits (2 of 50) [Show all]SpeciesId(%)Len(aa)
NP_150238.1 Mdh1 gene product R. norvegicus 99.1 333
XP_002709890.1 PREDICTED: cytosolic malate dehydrogenase O. cuniculus 98.5 333

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; mixed; embryonic tissue; muscle; lung; uncharacterized tissue; eye; heart; uterus; kidney; pancreas; liver; mammary gland; intestine; thyroid; pharynx; placenta; testis; parathyroid; ovary; blood; prostate; bone; bone marrow; connective tissue; lymph node; stomach; bladder; ascites; salivary gland; ear; vascular; lymph; pituitary gland; adrenal gland; pineal gland; cervix; larynx; adipose tissue; mouth; esophagus; thymus; epididymis; nerve; spinal cord; umbilical cord; trachea
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p13.3
UniSTS entry: Chr 2 MDH1
UniSTS entry: Chr 2 SHGC-31543 [Map Viewer]
UniSTS entry: Chr 2 RH16368
UniSTS entry: Chr 2 D2S1567E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_005917.3 Homo sapiens malate dehydrogenase 1, NAD (soluble) (MDH1), transcript variant 2, mRNA PA
CR457405.1 Homo sapiens full open reading frame cDNA clone RZPDo834A0714D for gene MDH1, malate dehydrogenase 1, NAD (soluble); complete cds, incl. stopcodon P
D55654.1 Homo sapiens mRNA for cytosolic malate dehydrogenase, complete cds P
U20352.1 Homo sapiens malate dehydrogenase (MDHA) mRNA, complete cds P
BC001484.2 Homo sapiens malate dehydrogenase 1, NAD (soluble), mRNA (cDNA clone MGC:1375 IMAGE:3505345), complete cds PA
AK307273.1 Homo sapiens cDNA, FLJ97221
AK312331.1 Homo sapiens cDNA, FLJ92645, Homo sapiens malate dehydrogenase 1, NAD (soluble) (MDH1), mRNA P
AL832067.1 Homo sapiens mRNA; cDNA DKFZp313K2018 (from clone DKFZp313K2018) A
AK300719.1 Homo sapiens cDNA FLJ52206 complete cds, highly similar to Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) PA
AK295931.1 Homo sapiens cDNA FLJ50971 complete cds, highly similar to Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) P
NM_001199112.1 Homo sapiens malate dehydrogenase 1, NAD (soluble) (MDH1), transcript variant 3, mRNA PA
NM_001199111.1 Homo sapiens malate dehydrogenase 1, NAD (soluble) (MDH1), transcript variant 1, mRNA PA

EST sequences (10 of 1617) [Show all sequences]

AA962045.1 Clone IMAGE:1592307 kidney 3' read P
R15814.1 Clone IMAGE:53316 brain 3' read A
AA974201.1 Clone IMAGE:1586730 uncharacterized tissue 3' read P
AA975119.1 Clone IMAGE:1555893 uncharacterized tissue 3' read A
AA976798.1 Clone IMAGE:1586898 uncharacterized tissue 3' read PA
AA996168.1 Clone IMAGE:1606501 kidney 3' read PA
AA902446.1 Clone IMAGE:1519322 uncharacterized tissue 3' read P
AI002053.1 Clone IMAGE:1637821 mammary gland 3' read P
AI025386.1 Clone IMAGE:1648066 parathyroid 3' read PA
AI027394.1 Clone IMAGE:1650133 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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