> Lysine (K)-specific demethylase 2B (KDM2B)
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UGID:915547     UniGene Hs.524800     Homo sapiens (human)   KDM2B Order cDNA clone, Links
Lysine (K)-specific demethylase 2B (KDM2B)

Human protein-coding gene KDM2B. Represented by 239 ESTs from 137 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 915547 - Hs.524800]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001164996.1 PREDICTED: lysine-specific demethylase 2B isoform 8 P. troglodytes 100.0 1335
NP_115979.3 KDM2B gene product H. sapiens 100.0 1335
NP_001003953.1 Kdm2b gene product M. musculus 97.6 1308
NP_001085840.1 lysine-specific demethylase 2B X. laevis 86.6 1258
XP_708792.5 PREDICTED: lysine-specific demethylase 2B isoform 2 D. rerio 80.0 733
NP_649864.2 lysine (K)-specific demethylase 2, isoform B D. melanogaster 67.6 346
NP_498419.2 Protein JHDM-1, isoform b C. elegans 49.8 307
Other hits (2 of 39) [Show all]SpeciesId(%)Len(aa)
XP_003907339.1 PREDICTED: lysine-specific demethylase 2B, partial P. anubis 99.3 1262
XP_002719783.1 PREDICTED: F-box and leucine-rich repeat protein 11-like isoform 2 O. cuniculus 98.9 1304

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; embryonic tissue; mammary gland; mixed; intestine; placenta; testis; pancreas; thyroid; skin; lung; eye; cervix; uterus; prostate; lymph node; blood; connective tissue; heart; trachea; thymus; ganglia; tonsil; bladder; ascites; stomach; kidney; parathyroid; lymph; mouth; bone; ear; liver
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q24.31
UniSTS entry: Chr 12 SHGC-56772
UniSTS entry: Chr 12 RH94276
UniSTS entry: Chr 12 RH103626
UniSTS entry: Chr 12 SGC32343 [Map Viewer]
UniSTS entry: Chr 12 SGC31344 [Map Viewer]
UniSTS entry: Chr 1 D15S1477
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

NM_032590.4 Homo sapiens lysine (K)-specific demethylase 2B (KDM2B), transcript variant 1, mRNA P
BX648928.1 Homo sapiens mRNA; cDNA DKFZp686A1784 (from clone DKFZp686A1784) PA
AK127328.1 Homo sapiens cDNA FLJ45399 fis, clone BRHIP3028246, highly similar to JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) P
NM_001005366.1 Homo sapiens lysine (K)-specific demethylase 2B (KDM2B), transcript variant 2, mRNA PA
AB031230.1 Homo sapiens PCCX2 mRNA for protein containing CXXC domain 2, partial cds P
BC115380.1 Homo sapiens F-box and leucine-rich repeat protein 10, mRNA (cDNA clone MGC:134812 IMAGE:40029132), complete cds P
BC115379.1 Homo sapiens F-box and leucine-rich repeat protein 10, mRNA (cDNA clone IMAGE:40029130), complete cds P
AK027692.1 Homo sapiens cDNA FLJ14786 fis, clone NT2RP4000737, moderately similar to Mus musculus F-box protein FBL10 mRNA P
AK027440.1 Homo sapiens cDNA FLJ14534 fis, clone NT2RM2000599, weakly similar to Homo sapiens F-box protein Lilina (LILINA) mRNA P
BC008735.2 Homo sapiens F-box and leucine-rich repeat protein 10, mRNA (cDNA clone IMAGE:3163445), partial cds PA
AK055282.1 Homo sapiens cDNA FLJ30720 fis, clone FCBBF2001720
AJ459424.1 Homo sapiens mRNA for JEMMA protein (PCCX2 gene) P
AK299827.1 Homo sapiens cDNA FLJ55590 complete cds, highly similar to JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) P
AK074718.1 Homo sapiens cDNA FLJ90237 fis, clone NT2RM2000622 P
BC028612.1 Homo sapiens cDNA clone IMAGE:4812413, containing frame-shift errors PA
AK316470.1 Homo sapiens cDNA, FLJ79369 complete cds, highly similar to JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) P

EST sequences (10 of 239) [Show all sequences]

AA907525.1 Clone IMAGE:1521855 lung 3' read
R17615.1 Clone IMAGE:32346 brain 5' read
AA923479.1 Clone IMAGE:1534544 kidney 3' read
AI028506.1 Clone IMAGE:1649652 parathyroid 3' read A
CB045846.1 Clone IMAGE:3218557 intestine 5' read
R24473.1 Clone IMAGE:132983 placenta 5' read
BX114917.1 Clone IMAGp998C234608_;_IMAGE:1881166 lung A
BX111068.1 Clone IMAGp998F05440_;_IMAGE:221572 eye A
CB109040.1 Clone L6ChoCK0-2-A09 liver 5' read
CB152430.1 Clone C1SNU17-39-C03 cervix 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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