> Cytochrome P450, family 27, subfamily B, polypeptide 1 (CYP27B1)
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UGID:915275     UniGene Hs.524528     Homo sapiens (human)   CYP27B1 Order cDNA clone, Links
Cytochrome P450, family 27, subfamily B, polypeptide 1 (CYP27B1)

Human protein-coding gene CYP27B1. Represented by 89 ESTs from 40 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_000785.3. [UniGene 915275 - Hs.524528]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000776.1 CYP27B1 gene product H. sapiens 100.0 507
XP_509175.2 PREDICTED: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial P. troglodytes 99.6 507
NP_034139.2 Cyp27b1 gene product M. musculus 84.2 506
XP_003199448.1 PREDICTED: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like D. rerio 56.6 467
NP_001087098.1 sterol 26-hydroxylase, mitochondrial X. laevis 47.6 191
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_001116450.1 PREDICTED: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like M. mulatta 96.8 507
XP_003906736.1 PREDICTED: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like P. anubis 96.3 507

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: kidney; eye; lung; uncharacterized tissue; pancreas; stomach; mammary gland; mixed; uterus; brain; muscle; bladder; blood; intestine; lymph node; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q13.1-q13.3
UniSTS entry: Chr 12 RH48116 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

NM_000785.3 Homo sapiens cytochrome P450, family 27, subfamily B, polypeptide 1 (CYP27B1), nuclear gene encoding mitochondrial protein, mRNA PA
AF246895.1 Homo sapiens 25-hydroxyvitamin D-1-alpha-hydroxylase mRNA, complete cds; nuclear gene for mitochondrial product P
DQ925371.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 10 mRNA, partial sequence, alternatively spliced P
DQ925370.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 9 mRNA, partial sequence, alternatively spliced P
DQ925369.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 8 mRNA, partial sequence, alternatively spliced P
DQ925368.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 7 mRNA, partial sequence, alternatively spliced P
DQ925367.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 6 mRNA, partial sequence, alternatively spliced P
DQ925366.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 5 mRNA, partial sequence, alternatively spliced P
DQ925365.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 4 mRNA, partial sequence, alternatively spliced
DQ925364.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 3 mRNA, partial sequence, alternatively spliced P
DQ925363.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 2 mRNA, partial sequence, alternatively spliced P
DQ925362.1 Homo sapiens vitamin D 1-alpha-hydroxylase splice variant 1 (CYP27B1) mRNA, partial sequence, alternatively spliced P
AK314953.1 Homo sapiens cDNA, FLJ95866, highly similar to Homo sapiens cytochrome P450, family 27, subfamily B, polypeptide 1(CYP27B1), nuclear gene encoding mitochondrial protein, mRNA P
BC136386.1 Homo sapiens cytochrome P450, family 27, subfamily B, polypeptide 1, mRNA (cDNA clone MGC:167996 IMAGE:9020373), complete cds P
AB005989.1 Homo sapiens mRNA for 25-hydroxyvitamin D3 1alpha-hydroxylase, complete cds P
AF020192.1 Homo sapiens 25-hydroxyvitamin D-1-alpha-hydroxylase (CYP1) mRNA, complete cds PA
AB005038.1 Homo sapiens mRNA for 25-hydroxyvitamin D3 1-alpha-hydroxylase, complete cds P

EST sequences (10 of 89) [Show all sequences]

AA962620.1 Clone IMAGE:1553660 kidney 3' read A
BX111995.1 Clone IMAGp998C055632_;_IMAGE:2274364 uterus P
AI222585.1 Clone IMAGE:1761925 kidney 3' read A
AI433907.1 Clone IMAGE:2130783 kidney 3' read P
AI473128.1 Clone IMAGE:2122285 kidney 3' read A
AI471301.1 Clone IMAGE:2044080 lymph node 3' read A
AI471782.1 Clone IMAGE:2137016 kidney 3' read P
AI493132.1 Clone IMAGE:2030300 kidney 3' read P
AI521214.1 Clone IMAGE:2122513 kidney 3' read P
AI522157.1 Clone IMAGE:2138163 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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