> Signal transducer and activator of transcription 6, interleukin-4 induced (STAT6)
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UGID:915265     UniGene Hs.524518     Homo sapiens (human)   STAT6 Order cDNA clone, Links
Signal transducer and activator of transcription 6, interleukin-4 induced (STAT6)

Human protein-coding gene STAT6. Represented by 933 ESTs from 350 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 915265 - Hs.524518]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003144.3 STAT6 gene product H. sapiens 100.0 846
XP_003906682.1 PREDICTED: signal transducer and activator of transcription 6 isoform 1 P. anubis 99.7 846
XP_001115590.1 PREDICTED: signal transducer and activator of transcription 6 isoform 1 M. mulatta 99.5 846
NP_033310.2 Stat6 gene product M. musculus 92.7 836
NP_001088631.1 signal transducer and activator of transcription 6, interleukin-4 induced X. laevis 63.7 766
NP_001003984.1 stat5.2 gene product D. rerio 54.1 495
NP_732517.2 Signal-transducer and activator of transcription protein at 92E, isoform B D. melanogaster 45.0 211
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_003952193.1 PREDICTED: LOW QUALITY PROTEIN: signal transducer and activator of transcription 6 P. troglodytes 99.4 857
XP_003355536.2 PREDICTED: signal transducer and activator of transcription 6-like S. scrofa 96.8 846

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uterus; mouth; uncharacterized tissue; thymus; testis; brain; lung; intestine; connective tissue; kidney; blood; bladder; ear; amniotic fluid; trachea; mixed; larynx; placenta; skin; prostate; liver; mammary gland; eye; lymph; adrenal gland; muscle; heart; bone; ovary; lymph node; spleen; thyroid; embryonic tissue; umbilical cord; vascular; pancreas; parathyroid; stomach; bone marrow; nerve; pharynx; epididymis; tonsil; cervix; ascites; esophagus; salivary gland; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q13
UniSTS entry: Chr 12 A009O16 [Map Viewer]
UniSTS entry: Chr 12 RH44534 [Map Viewer]
UniSTS entry: Chr 12 G32703
UniSTS entry: Chr 12 RH70573
UniSTS entry: Chr 12 G54117
UniSTS entry: MARC_2391-2392:991932733:1
UniSTS entry: Chr 12 D12S1644 [Map Viewer]
UniSTS entry: Chr 12 STAT6_856
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (21)

BT007380.1 Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced mRNA, complete cds P
NM_003153.4 Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2, mRNA PA
BC075852.1 Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced, mRNA (cDNA clone MGC:90177 IMAGE:5530399), complete cds PA
AB103089.1 Homo sapiens STAT6 mRNA for signal transducer and activator of transcription 6 nirs variant 2, complete cds P
AB103088.1 Homo sapiens STAT6 mRNA for signal transducer and activator of transcription 6 nirs variant 1, complete cds
U16031.1 Human transcription factor IL-4 Stat mRNA, complete cds P
BC004973.1 Homo sapiens cDNA clone IMAGE:2958389, containing frame-shift errors PA
BC005823.2 Homo sapiens cDNA clone IMAGE:2958389, containing frame-shift errors PA
AK290431.1 Homo sapiens cDNA FLJ77813 complete cds, highly similar to Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), mRNA P
AK291044.1 Homo sapiens cDNA FLJ77755 complete cds, highly similar to Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), mRNA P
AK308751.1 Homo sapiens cDNA, FLJ98792 P
AK312471.1 Homo sapiens cDNA, FLJ92827, highly similar to Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), mRNA P
AK299094.1 Homo sapiens cDNA FLJ51958 complete cds, highly similar to Signal transducer and activator of transcription 6 P
AK298721.1 Homo sapiens cDNA FLJ51956 complete cds, highly similar to Signal transducer and activator of transcription 6 P
AK316236.1 Homo sapiens cDNA, FLJ79135 complete cds, highly similar to Signal transducer and activator of transcription 6 P
AK316142.1 Homo sapiens cDNA, FLJ79041 complete cds, highly similar to Signal transducer and activator of transcription 6 P
NM_001178081.1 Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 5, mRNA PA
NM_001178080.1 Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 4, mRNA PA
NM_001178079.1 Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 3, mRNA PA
NM_001178078.1 Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 1, mRNA PA
NR_033659.1 Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 6, non-coding RNA PA

EST sequences (10 of 933) [Show all sequences]

AA984943.1 Clone IMAGE:1576717 spleen 3' read
AI026017.1 Clone IMAGE:1645756 parathyroid 3' read A
AI027032.1 Clone IMAGE:1649459 parathyroid 3' read A
AI033025.1 Clone IMAGE:1654351 mixed 3' read
AI082533.1 Clone IMAGE:1660264 embryonic tissue 3' read A
AI092443.1 Clone IMAGE:1683427 parathyroid 3' read A
AI095580.1 Clone IMAGE:1696773 uterus 3' read A
AI131403.1 Clone IMAGE:1709978 heart 3' read A
BX107210.1 Clone IMAGp998E17110_;_IMAGE:120184 mixed P
AI263069.1 Clone IMAGE:2028346 kidney 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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