> Mitochondrial calcium uptake 1 (MICU1)
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UGID:915114     UniGene Hs.524367     Homo sapiens (human)   MICU1
Mitochondrial calcium uptake 1 (MICU1)

Human protein-coding gene MICU1. Represented by 784 ESTs from 278 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 915114 - Hs.524367]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006068.2 MICU1 gene product H. sapiens 100.0 477
XP_003339234.1 PREDICTED: calcium uptake protein 1, mitochondrial isoform 2 P. troglodytes 100.0 277
XP_003903840.1 PREDICTED: calcium uptake protein 1, mitochondrial-like P. anubis 99.7 329
NP_659071.1 Micu1 gene product M. musculus 97.9 476
NP_001077302.1 micu1 gene product D. rerio 87.7 488
NP_001084813.1 mitochondrial calcium uptake 1 X. laevis 75.1 181
NP_001097110.1 CG4495, isoform B D. melanogaster 60.6 396
NP_001255723.1 Protein MICU-1, isoform d C. elegans 54.2 382
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_001104987.2 PREDICTED: calcium-binding atopy-related autoantigen 1-like isoform 1 M. mulatta 98.4 493
XP_536383.3 PREDICTED: calcium uptake protein 1, mitochondrial C. lupus familiaris 98.3 479

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; mixed; uncharacterized tissue; testis; mouth; skin; lung; cervix; uterus; pituitary gland; bone marrow; eye; heart; vascular; muscle; intestine; spleen; liver; pharynx; ovary; placenta; mammary gland; blood; embryonic tissue; connective tissue; thymus; adrenal gland; bone; lymph; umbilical cord; amniotic fluid; ascites; pancreas; prostate; stomach; ear; trachea; bladder; thyroid; larynx; pineal gland; lymph node; esophagus; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q22.1
UniSTS entry: Chr 10 RH11031
UniSTS entry: Chr 10 RH80361
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

Y17711.1 Homo sapiens mRNA for atopy related autoantigen CALC PA
AL117423.1 Homo sapiens mRNA; cDNA DKFZp564C246 (from clone DKFZp564C246) PA
AK022697.1 Homo sapiens cDNA FLJ12635 fis, clone NT2RM4001865, highly similar to Homo sapiens mRNA for atopy related autoantigen CALC P
AK023318.1 Homo sapiens cDNA FLJ13256 fis, clone OVARC1000834, highly similar to Homo sapiens calcium binding atopy-related autoantigen 1 (CBARA1), mRNA P
NM_006077.3 Homo sapiens mitochondrial calcium uptake 1 (MICU1), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA P
AK225695.1 Homo sapiens mRNA for calcium binding atopy-related autoantigen 1 variant, clone: SYN04411 P
AK225298.1 Homo sapiens mRNA for calcium binding atopy-related autoantigen 1 variant, clone: HEP03393 PA
BC004216.2 Homo sapiens calcium binding atopy-related autoantigen 1, mRNA (cDNA clone MGC:4521 IMAGE:3009677), complete cds PA
BC004190.2 Homo sapiens calcium binding atopy-related autoantigen 1, mRNA (cDNA clone MGC:2891 IMAGE:3009677), complete cds PA
BC016641.1 Homo sapiens calcium binding atopy-related autoantigen 1, mRNA (cDNA clone MGC:17962 IMAGE:3919114), complete cds PA
AK298347.1 Homo sapiens cDNA FLJ54801 complete cds, highly similar to Homo sapiens calcium binding atopy-related autoantigen 1 (CBARA1), mRNA P
AK296086.1 Homo sapiens cDNA FLJ54794 complete cds, highly similar to Homo sapiens calcium binding atopy-related autoantigen 1 (CBARA1), mRNA PA
NM_001195519.1 Homo sapiens mitochondrial calcium uptake 1 (MICU1), transcript variant 3, mRNA P
NM_001195518.1 Homo sapiens mitochondrial calcium uptake 1 (MICU1), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA P

EST sequences (10 of 784) [Show all sequences]

AA954674.1 Clone IMAGE:1554927 kidney 3' read A
AA864442.1 Clone IMAGE:1456554 kidney 3' read A
AA970995.1 Clone IMAGE:1581946 mixed 3' read P
AA983287.1 Clone IMAGE:1592505 kidney 3' read A
AA989138.1 Clone IMAGE:1593500 kidney 3' read A
AA995470.1 Clone IMAGE:1610401 uncharacterized tissue 3' read
R17270.1 Clone IMAGE:31714 brain 5' read P
AA907067.1 Clone IMAGE:1540675 mixed 3' read A
AI016960.1 Clone IMAGE:1627546 mixed 3' read A
AI023689.1 Clone IMAGE:1654218 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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