> Cyclin D1 (CCND1)
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UGID:914599     UniGene Hs.523852     Homo sapiens (human)   CCND1
Cyclin D1 (CCND1)

Human protein-coding gene CCND1. Represented by 1120 ESTs from 370 cDNA libraries. Corresponds to reference sequence NM_053056.2. [UniGene 914599 - Hs.523852]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001101029.1 PREDICTED: g1/S-specific cyclin-D1 M. mulatta 100.0 294
XP_003909472.1 PREDICTED: G1/S-specific cyclin-D1 P. anubis 100.0 294
NP_444284.1 CCND1 gene product H. sapiens 100.0 294
NP_031657.1 Ccnd1 gene product M. musculus 97.3 294
NP_001079474.1 G1/S-specific cyclin-D1 b X. laevis 87.2 289
NP_571100.1 ccnd1 gene product D. rerio 83.5 290
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_003952008.1 PREDICTED: LOW QUALITY PROTEIN: G1/S-specific cyclin-D1 P. troglodytes 98.4 378
NP_741989.3 Ccnd1 gene product R. norvegicus 97.3 294

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: skin; brain; embryonic tissue; intestine; mammary gland; lung; pancreas; mixed; eye; prostate; kidney; placenta; connective tissue; ascites; bladder; thyroid; liver; uterus; bone; ovary; trachea; larynx; testis; uncharacterized tissue; heart; vascular; adrenal gland; stomach; muscle; blood; bone marrow; adipose tissue; mouth; epididymis; cervix; lymph node; pituitary gland; esophagus; amniotic fluid; thymus; pharynx; ganglia; lymph; nerve; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q13
UniSTS entry: Chr 11 RH67810 [Map Viewer]
UniSTS entry: Chr 11 PMC303366P1
UniSTS entry: Chr 11 PMC98458P1
UniSTS entry: Chr 11 PMC321442P2
UniSTS entry: Chr 11 WI-16756 [Map Viewer]
UniSTS entry: Chr 11 GDB:197910
UniSTS entry: Chr 11 CCND1 [Map Viewer]
UniSTS entry: GDB:371378
UniSTS entry: Chr 11 CCND1_504
UniSTS entry: Chr 11 GDB:181402
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

M64349.1 Human cyclin D (cyclin D1) mRNA, complete cds PA
CR536538.1 Homo sapiens full open reading frame cDNA clone RZPDo834E0520D for gene CCND1, cyclin D1 (PRAD1: parathyroid adenomatosis 1); complete cds, incl. stopcodon P
CR542099.1 Homo sapiens full open reading frame cDNA clone RZPDo834A1237D for gene CCND1, cyclin D1 (PRAD1: parathyroid adenomatosis 1); complete cds, without stopcodon P
BT019845.1 Homo sapiens cyclin D1 (PRAD1: parathyroid adenomatosis 1) mRNA, complete cds P
BT019844.1 Homo sapiens cyclin D1 (PRAD1: parathyroid adenomatosis 1) mRNA, complete cds P
M73554.1 Human bcl-1 mRNA, complete CDS P
AB075505.1 Homo sapiens neuroblastoma cDNA, clone:Nbla00347, full insert sequence
BC000076.2 Homo sapiens cyclin D1, mRNA (cDNA clone MGC:2316 IMAGE:3508088), complete cds PA
BC014078.2 Homo sapiens cyclin D1, mRNA (cDNA clone MGC:20169 IMAGE:4124540), complete cds PA
NM_053056.2 Homo sapiens cyclin D1 (CCND1), mRNA PA
BC001501.2 Homo sapiens cyclin D1, mRNA (cDNA clone MGC:2233 IMAGE:3507598), complete cds PA
AK313136.1 Homo sapiens cDNA, FLJ93625, Homo sapiens cyclin D1 (PRAD1: parathyroid adenomatosis 1) (CCND1),mRNA P
BC025302.1 Homo sapiens cyclin D1, mRNA (cDNA clone MGC:39267 IMAGE:5457963), complete cds PA
AK299044.1 Homo sapiens cDNA FLJ51281 complete cds, highly similar to G1/S-specific cyclin-D1 P
S71637.1 cyclin D1 {3' truncated transcript} [human, breast cancer cell line MDA MB-453, mRNA Partial Mutant, 117 nt]
X59798.1 Human PRAD1 mRNA for cyclin PA
BC023620.2 Homo sapiens cyclin D1, mRNA (cDNA clone MGC:23386 IMAGE:4650919), complete cds PA
M74092.1 Human cyclin mRNA P

EST sequences (10 of 1120) [Show all sequences]

AA962503.1 Clone IMAGE:1573603 kidney 3' read A
AA983722.1 Clone IMAGE:1490874 skin 3' read A
AA994114.1 Clone IMAGE:1630798 mammary gland 3' read
AA906539.1 Clone IMAGE:1524027 mixed 3' read P
R18074.1 Clone IMAGE:32371 brain 5' read
AI023701.1 Clone IMAGE:1654223 mixed 3' read
AI042556.1 Clone IMAGE:1665082 skin 3' read P
AI055890.1 Clone IMAGE:1648336 parathyroid 3' read A
AI066484.1 Clone IMAGE:1679298 skin 3' read A
AI073353.1 Clone IMAGE:1679390 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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