> EPH receptor B2 (EPHB2)
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UGID:914076     UniGene Hs.523329     Homo sapiens (human)   EPHB2 Links
EPH receptor B2 (EPHB2)

Human protein-coding gene EPHB2. Represented by 170 ESTs from 101 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 914076 - Hs.523329]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004433.2 EPHB2 gene product H. sapiens 100.0 986
XP_003949368.1 PREDICTED: ephrin type-B receptor 2 isoform 1 P. troglodytes 100.0 980
NP_034272.1 Ephb2 gene product M. musculus 99.9 985
XP_852978.2 PREDICTED: ephrin type-B receptor 2 isoform 2 C. lupus familiaris 99.9 966
XP_003482041.1 PREDICTED: ephrin type-B receptor 2 isoform 3 S. scrofa 99.8 981
XP_003891356.1 PREDICTED: ephrin type-B receptor 2 P. anubis 99.8 956
XP_002716076.1 PREDICTED: EPH receptor B2-like O. cuniculus 99.7 1012
XP_001920022.2 PREDICTED: ephrin type-B receptor 2-like D. rerio 91.8 962
NP_001084070.1 ephrin type-B receptor 1-A precursor X. laevis 80.5 977
NP_726591.2 Eph receptor tyrosine kinase, isoform B D. melanogaster 64.7 552
NP_494807.1 Protein VAB-1, isoform a C. elegans 58.6 338
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
NP_001120791.1 Ephb2 gene product R. norvegicus 99.5 985
NP_001178427.1 ephrin type-B receptor 2 B. taurus 99.5 964

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: intestine; brain; eye; lung; muscle; stomach; placenta; embryonic tissue; uncharacterized tissue; kidney; testis; ovary; larynx; connective tissue; mouth; umbilical cord; heart; mammary gland; mixed; pancreas; bone; adipose tissue; liver; skin; uterus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p36.1-p35
UniSTS entry: Chr 1 MARC_17495-17496:1030378704:1
UniSTS entry: Chr 1 GDB:636068
UniSTS entry: Chr 1 GDB:593997
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

D14717.1 Homo sapiens mRNA for large erk kinase, partial cds P
BC067861.1 Homo sapiens EPH receptor B2, mRNA (cDNA clone IMAGE:30344215), complete cds PA
D31661.1 Homo sapiens ERK mRNA for tyrosine kinase, complete cds P
AB210018.1 Homo sapiens mRNA for EPHB2 variant protein, partial cds, clone: fj16004 P
D37827.1 Homo sapiens mRNA for large erk/cek5 tyrosine kinase, partial cds P
L41939.1 Homo sapiens (clone FBK III 11c) protein-tyrosine kinase (DRT) mRNA, complete cds P
L36643.1 Homo sapiens receptor protein-tyrosine kinase (HEK5) mRNA, 3' end P
NM_004442.6 Homo sapiens EPH receptor B2 (EPHB2), transcript variant 2, mRNA P
NM_017449.3 Homo sapiens EPH receptor B2 (EPHB2), transcript variant 1, mRNA P
BC018763.1 Homo sapiens EPH receptor B2, mRNA (cDNA clone IMAGE:3501578) PA
AK299701.1 Homo sapiens cDNA FLJ60851 complete cds, highly similar to Ephrin type-B receptor 2 precursor (EC 2.7.10.1) P
AK298898.1 Homo sapiens cDNA FLJ60805 complete cds, highly similar to Ephrin type-B receptor 2 precursor (EC 2.7.10.1) P
BC007903.2 Homo sapiens EPH receptor B2, mRNA (cDNA clone IMAGE:4138660) PA
HM437237.1 Homo sapiens ephrin type-B receptor 2 variant (EPHB2) mRNA, partial cds
BC041017.1 Homo sapiens EPH receptor B2, mRNA (cDNA clone IMAGE:3343843), with apparent retained intron PA
AF025304.1 Homo sapiens protein-tyrosine kinase EPHB2v (EPHB2) mRNA, complete cds PA

EST sequences (10 of 170) [Show all sequences]

AI038197.1 Clone IMAGE:1660083 embryonic tissue 3' read
AF071057.1 Clone GCYS-18 stomach
BX113022.1 Clone IMAGp998A08789_;_IMAGE:345103 heart
AI216739.1 Clone IMAGE:1884021 lung 3' read
AI268257.1 Clone IMAGE:1880748 lung 3' read A
CB161121.1 Clone L18POOL1n1-28-H04 liver 5' read
T06973.1 Clone HFBEB70 brain
AI337308.1 Clone IMAGE:2062345 intestine 3' read P
R39317.1 Clone IMAGE:24067 brain 3' read A
AI445236.1 Clone IMAGE:2154135 intestine 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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