> Prosaposin (PSAP)
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UGID:913751     UniGene Hs.523004     Homo sapiens (human)   PSAP Order cDNA clone, Links
Prosaposin (PSAP)

Human protein-coding gene PSAP. Represented by 5175 ESTs from 837 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 913751 - Hs.523004]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_507840.2 PREDICTED: proactivator polypeptide isoform 2 P. troglodytes 100.0 526
NP_001035930.1 PSAP gene product H. sapiens 100.0 526
XP_001107102.1 PREDICTED: proactivator polypeptide-like isoform 7 M. mulatta 99.6 526
XP_003903858.1 PREDICTED: proactivator polypeptide isoform 2 P. anubis 99.6 526
NP_035309.3 Psap gene product M. musculus 78.1 556
NP_001079822.1 uncharacterized protein LOC379512 precursor X. laevis 53.5 511
NP_571958.1 psap gene product D. rerio 51.5 521
Other hits (2 of 17) [Show all]SpeciesId(%)Len(aa)
XP_001503814.1 PREDICTED: proactivator polypeptide E. caballus 91.1 525
XP_861590.1 PREDICTED: proactivator polypeptide isoform 6 C. lupus familiaris 90.9 526

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; pancreas; lung; skin; uncharacterized tissue; prostate; uterus; eye; testis; embryonic tissue; intestine; kidney; mammary gland; thyroid; mixed; stomach; connective tissue; ovary; blood; bone marrow; esophagus; bone; liver; vascular; muscle; spleen; heart; thymus; nerve; adrenal gland; ganglia; pineal gland; parathyroid; pituitary gland; cervix; ascites; mouth; lymph; larynx; pharynx; adipose tissue; lymph node; amniotic fluid; tonsil; ear; umbilical cord; trachea; salivary gland; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q21-q22
UniSTS entry: Chr 10 RH11184 [Map Viewer]
UniSTS entry: Chr 10 STS-J03077
UniSTS entry: Chr 10 RH68874 [Map Viewer]
UniSTS entry: Chr 10 RH41802 [Map Viewer]
UniSTS entry: Chr 10 D10S2162
UniSTS entry: Chr 10 D10S1299E
UniSTS entry: Chr 10 D10S1303E
UniSTS entry: BE112969
UniSTS entry: Chr 15 WI-9202 [Map Viewer]
UniSTS entry: Chr 15 D15S636E [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (25)

M60255.1 Human mutant cerebroside sulfate activator protein (SAP-MU-9) mRNA, complete cds P
M60257.1 Human mutant cerebroside sulfate activator protein (SAP-MU-0) mRNA, complete cds, without the 9 bp insertion found in alternatively spliced mRNA P
M60258.1 Human mutant cerebroside sulfate activator protein (SAP-MU-6) mRNA, complete cds and with a 6 bp insertion P
BT006849.1 Homo sapiens prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) mRNA, complete cds P
AK129790.1 Homo sapiens cDNA FLJ26279 fis, clone DMC06755, highly similar to Proactivator polypeptide precursor P
CR456746.1 Homo sapiens full open reading frame cDNA clone RZPDo834F1114D for gene PSAP, prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy); complete cds, incl. stopcodon P
J03077.1 Human co-beta glucosidase (proactivator) mRNA, complete cds P
BC091483.1 Homo sapiens prosaposin, mRNA (cDNA clone IMAGE:6186106), complete cds PA
AB209776.1 Homo sapiens mRNA for prosaposin variant protein P
AK223290.1 Homo sapiens mRNA for prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) variant, clone: SYN03435 P
NM_002778.2 Homo sapiens prosaposin (PSAP), transcript variant 1, mRNA PA
J03015.1 Homo sapiens sphingolipid activator protein 1 mRNA, 3' end P
M32221.1 Human saposin proteins A-D mRNA, complete cds P
NM_001042466.1 Homo sapiens prosaposin (PSAP), transcript variant 3, mRNA PA
NM_001042465.1 Homo sapiens prosaposin (PSAP), transcript variant 2, mRNA PA
BC004275.1 Homo sapiens prosaposin, mRNA (cDNA clone MGC:10834 IMAGE:3615413), complete cds PA
BC007612.1 Homo sapiens prosaposin, mRNA (cDNA clone MGC:15695 IMAGE:3351606), complete cds PA
AK057878.1 Homo sapiens cDNA FLJ25149 fis, clone CBR07687, highly similar to PROACTIVATOR POLYPEPTIDE PRECURSOR P
BC001503.2 Homo sapiens prosaposin, mRNA (cDNA clone MGC:2254 IMAGE:3508263), complete cds PA
AK307721.1 Homo sapiens cDNA, FLJ97669 P
AK293672.1 Homo sapiens cDNA FLJ54596 complete cds, highly similar to Proactivator polypeptide precursor P
AK299184.1 Homo sapiens cDNA FLJ54136 complete cds, highly similar to Proactivator polypeptide precursor P
M12710.1 Human sphingolipid activator protein mRNA
M81355.1 Homo sapiens sphingolipid activator proteins 1 and 2 processed mutant mRNA, complete cds P
D00422.1 Homo sapiens mRNA for sphingolipid activator proteins, complete cds P

EST sequences (10 of 5175) [Show all sequences]

AA954944.1 Clone IMAGE:1574437 kidney 3' read A
AA865208.1 Clone IMAGE:1459125 kidney 3' read A
AA865505.1 Clone IMAGE:1459286 kidney 3' read A
AA962694.1 Clone IMAGE:1575478 intestine 3' read A
AA970628.1 Clone IMAGE:1574482 kidney 3' read A
AA971724.1 Clone IMAGE:1584595 lung 3' read A
AA973050.1 Clone IMAGE:1578458 mixed 3' read
AA973247.1 Clone IMAGE:1536816 kidney 3' read
AA989590.1 Clone IMAGE:1576942 spleen 3' read
AA991186.1 Clone IMAGE:1606314 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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